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Q7Z3U6

- Q7Z3U6_HUMAN

UniProt

Q7Z3U6 - Q7Z3U6_HUMAN

Protein
Submitted name:

Putative uncharacterized protein DKFZp686C2469

Gene

DKFZp686C2469

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 69 (01 Oct 2014)
      Sequence version 1 (01 Oct 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. guanyl-nucleotide exchange factor activity Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of small GTPase mediated signal transduction Source: InterPro
    2. small GTPase mediated signal transduction Source: InterPro

    Keywords - Molecular functioni

    Guanine-nucleotide releasing factorSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized protein DKFZp686C2469Imported
    Gene namesi
    Name:DKFZp686C2469Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. intracellular Source: InterPro

    PTM / Processingi

    Proteomic databases

    PRIDEiQ7Z3U6.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7Z3U6.
    SMRiQ7Z3U6. Positions 682-769.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains N-terminal Ras-GEF domain.SAAS annotation
    Contains Ras-GEF domain.SAAS annotation

    Phylogenomic databases

    HOVERGENiHBG005864.

    Family and domain databases

    Gene3Di1.10.840.10. 2 hits.
    InterProiIPR000159. Ras-assoc.
    IPR000651. Ras-like_Gua-exchang_fac_N.
    IPR019804. Ras_G-nucl-exch_fac_CS.
    IPR023578. Ras_GEF_dom.
    IPR001895. RasGRF_CDC25.
    IPR029071. Ubiquitin-rel_dom.
    [Graphical view]
    PfamiPF00788. RA. 1 hit.
    PF00617. RasGEF. 1 hit.
    PF00618. RasGEF_N. 1 hit.
    [Graphical view]
    SMARTiSM00314. RA. 1 hit.
    SM00147. RasGEF. 1 hit.
    SM00229. RasGEFN. 1 hit.
    [Graphical view]
    SUPFAMiSSF48366. SSF48366. 2 hits.
    SSF54236. SSF54236. 1 hit.
    PROSITEiPS50200. RA. 1 hit.
    PS00720. RASGEF. 1 hit.
    PS50009. RASGEF_CAT. 1 hit.
    PS50212. RASGEF_NTER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7Z3U6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEVKPVGEPT QEVSKFKLST KVESTGHWLV EDHVRIWEVL KTEESSIQDW    50
    GEEVEEGAVY HVTLKRVQIQ QAANKGARWL GVEGDQLPPG HAVSQYETCK 100
    IRTIKAGTLE KLVENLLTAF GDNDFTYISI FLSTYRGFAS TKEVLELLLD 150
    RYGNLTSPNC EEDGSQSSSE SKMVIRNAIA SILRAWLDQC AEDFREPPHF 200
    PCLQKLLDYL TRMMPGSDPE RRAQNLLEQF QKQEVETDNG LPNTISFSLE 250
    EEEELEGGES AEFTCFSEDL VAEQLTYMDA QLFKKVVPHH CLGCIWSRRD 300
    KKENKHLAPT IRATISQFNT LTKCVVSTIL GGKELKTQQR AKIIEKWINI 350
    AHECRLLKNF SSLRAIVSAL QSNSIYRLKK TWAAVPRDRM LMFEELSDIF 400
    SDHNNHLTSR ELLMKEGTSK FANLDSSVKE NQKRTQRRLQ LQKDMGVMQG 450
    TVPYLGTFLT DLTMLDTALQ DYIEGGLVNF EKRRREFEVI AQIKLLQSAC 500
    NSYCMTPDQK FIQWFQRQQL LTEEESYALS CEIEAAADAS TTSPKPRKSM 550
    VKRLSLLFLG SDMITSPTPT KEQPKSTASG SSGESMDSVS VSSCESNHSE 600
    AEEGSITPMD TPDEPQKKLS ESSSSCSSIH SMDTNSSGMS SLINPLSSPP 650
    SCNNNPKIHK RSVSVTSITS TVLPPVYNQQ NEDTCIIRIS VEDNNGNMYK 700
    SIMLTSQDKT PAVIQRAMLK HNLDSDPAEE YELVQVISED KELVIPDSAN 750
    VFYAMNSQVN FDFILRKKNS MEEQVKLRSR TSLTLPRTAK RGCWSNRHSK 800
    ITL 803
    Length:803
    Mass (Da):90,646
    Last modified:October 1, 2003 - v1
    Checksum:iE411018F59BAED85
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX537416 mRNA. Translation: CAD97658.1.
    UniGeneiHs.497148.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX537416 mRNA. Translation: CAD97658.1 .
    UniGenei Hs.497148.

    3D structure databases

    ProteinModelPortali Q7Z3U6.
    SMRi Q7Z3U6. Positions 682-769.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q7Z3U6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG005864.

    Family and domain databases

    Gene3Di 1.10.840.10. 2 hits.
    InterProi IPR000159. Ras-assoc.
    IPR000651. Ras-like_Gua-exchang_fac_N.
    IPR019804. Ras_G-nucl-exch_fac_CS.
    IPR023578. Ras_GEF_dom.
    IPR001895. RasGRF_CDC25.
    IPR029071. Ubiquitin-rel_dom.
    [Graphical view ]
    Pfami PF00788. RA. 1 hit.
    PF00617. RasGEF. 1 hit.
    PF00618. RasGEF_N. 1 hit.
    [Graphical view ]
    SMARTi SM00314. RA. 1 hit.
    SM00147. RasGEF. 1 hit.
    SM00229. RasGEFN. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48366. SSF48366. 2 hits.
    SSF54236. SSF54236. 1 hit.
    PROSITEi PS50200. RA. 1 hit.
    PS00720. RASGEF. 1 hit.
    PS50009. RASGEF_CAT. 1 hit.
    PS50212. RASGEF_NTER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Ansorge W., Krieger S., Regiert T., Rittmueller C., Schwager B., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S.
      Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Human endometrium carcinoma cell lineImported.

    Entry informationi

    Entry nameiQ7Z3U6_HUMAN
    AccessioniPrimary (citable) accession number: Q7Z3U6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2003
    Last sequence update: October 1, 2003
    Last modified: October 1, 2014
    This is version 69 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.