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Protein
Submitted name:

Uncharacterized protein DKFZp686C2469

Gene

DKFZp686C2469

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGuanine-nucleotide releasing factorPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized protein DKFZp686C2469Imported
Gene namesi
Name:DKFZp686C2469Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ7Z3U6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini100 – 231N-terminal Ras-GEFInterPro annotationAdd BLAST132
Domaini267 – 536Ras-GEFInterPro annotationAdd BLAST270
Domaini683 – 770Ras-associatingInterPro annotationAdd BLAST88

Phylogenomic databases

eggNOGiKOG3629 Eukaryota
ENOG410ZUT5 LUCA
HOVERGENiHBG005864

Family and domain databases

CDDicd00155 RasGEF, 1 hit
cd06224 REM, 1 hit
Gene3Di1.10.840.101 hit
InterProiView protein in InterPro
IPR000159 RA_dom
IPR000651 Ras-like_Gua-exchang_fac_N
IPR019804 Ras_G-nucl-exch_fac_CS
IPR023578 Ras_GEF_dom_sf
IPR001895 RASGEF_cat_dom
IPR036964 RASGEF_cat_dom_sf
IPR030748 RGL1
IPR029071 Ubiquitin-like_domsf
PANTHERiPTHR23113:SF199 PTHR23113:SF199, 1 hit
PfamiView protein in Pfam
PF00788 RA, 1 hit
PF00617 RasGEF, 1 hit
PF00618 RasGEF_N, 1 hit
SMARTiView protein in SMART
SM00314 RA, 1 hit
SM00147 RasGEF, 1 hit
SM00229 RasGEFN, 1 hit
SUPFAMiSSF48366 SSF48366, 2 hits
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50200 RA, 1 hit
PS00720 RASGEF, 1 hit
PS50009 RASGEF_CAT, 1 hit
PS50212 RASGEF_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q7Z3U6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEVKPVGEPT QEVSKFKLST KVESTGHWLV EDHVRIWEVL KTEESSIQDW
60 70 80 90 100
GEEVEEGAVY HVTLKRVQIQ QAANKGARWL GVEGDQLPPG HAVSQYETCK
110 120 130 140 150
IRTIKAGTLE KLVENLLTAF GDNDFTYISI FLSTYRGFAS TKEVLELLLD
160 170 180 190 200
RYGNLTSPNC EEDGSQSSSE SKMVIRNAIA SILRAWLDQC AEDFREPPHF
210 220 230 240 250
PCLQKLLDYL TRMMPGSDPE RRAQNLLEQF QKQEVETDNG LPNTISFSLE
260 270 280 290 300
EEEELEGGES AEFTCFSEDL VAEQLTYMDA QLFKKVVPHH CLGCIWSRRD
310 320 330 340 350
KKENKHLAPT IRATISQFNT LTKCVVSTIL GGKELKTQQR AKIIEKWINI
360 370 380 390 400
AHECRLLKNF SSLRAIVSAL QSNSIYRLKK TWAAVPRDRM LMFEELSDIF
410 420 430 440 450
SDHNNHLTSR ELLMKEGTSK FANLDSSVKE NQKRTQRRLQ LQKDMGVMQG
460 470 480 490 500
TVPYLGTFLT DLTMLDTALQ DYIEGGLVNF EKRRREFEVI AQIKLLQSAC
510 520 530 540 550
NSYCMTPDQK FIQWFQRQQL LTEEESYALS CEIEAAADAS TTSPKPRKSM
560 570 580 590 600
VKRLSLLFLG SDMITSPTPT KEQPKSTASG SSGESMDSVS VSSCESNHSE
610 620 630 640 650
AEEGSITPMD TPDEPQKKLS ESSSSCSSIH SMDTNSSGMS SLINPLSSPP
660 670 680 690 700
SCNNNPKIHK RSVSVTSITS TVLPPVYNQQ NEDTCIIRIS VEDNNGNMYK
710 720 730 740 750
SIMLTSQDKT PAVIQRAMLK HNLDSDPAEE YELVQVISED KELVIPDSAN
760 770 780 790 800
VFYAMNSQVN FDFILRKKNS MEEQVKLRSR TSLTLPRTAK RGCWSNRHSK

ITL
Length:803
Mass (Da):90,646
Last modified:October 1, 2003 - v1
Checksum:iE411018F59BAED85
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX537416 mRNA Translation: CAD97658.1
UniGeneiHs.497148

Similar proteinsi

Entry informationi

Entry nameiQ7Z3U6_HUMAN
AccessioniPrimary (citable) accession number: Q7Z3U6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: April 25, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.