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Q7Z3U6 (Q7Z3U6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:DKFZp686C2469 EMBL CAD97658.1
OrganismHomo sapiens (Human) EMBL CAD97658.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length803 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains N-terminal Ras-GEF domain. SAAS SAAS023578

Contains Ras-GEF domain. SAAS SAAS023578

Sequences

Sequence LengthMass (Da)Tools
Q7Z3U6 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: E411018F59BAED85

FASTA80390,646
        10         20         30         40         50         60 
MEVKPVGEPT QEVSKFKLST KVESTGHWLV EDHVRIWEVL KTEESSIQDW GEEVEEGAVY 

        70         80         90        100        110        120 
HVTLKRVQIQ QAANKGARWL GVEGDQLPPG HAVSQYETCK IRTIKAGTLE KLVENLLTAF 

       130        140        150        160        170        180 
GDNDFTYISI FLSTYRGFAS TKEVLELLLD RYGNLTSPNC EEDGSQSSSE SKMVIRNAIA 

       190        200        210        220        230        240 
SILRAWLDQC AEDFREPPHF PCLQKLLDYL TRMMPGSDPE RRAQNLLEQF QKQEVETDNG 

       250        260        270        280        290        300 
LPNTISFSLE EEEELEGGES AEFTCFSEDL VAEQLTYMDA QLFKKVVPHH CLGCIWSRRD 

       310        320        330        340        350        360 
KKENKHLAPT IRATISQFNT LTKCVVSTIL GGKELKTQQR AKIIEKWINI AHECRLLKNF 

       370        380        390        400        410        420 
SSLRAIVSAL QSNSIYRLKK TWAAVPRDRM LMFEELSDIF SDHNNHLTSR ELLMKEGTSK 

       430        440        450        460        470        480 
FANLDSSVKE NQKRTQRRLQ LQKDMGVMQG TVPYLGTFLT DLTMLDTALQ DYIEGGLVNF 

       490        500        510        520        530        540 
EKRRREFEVI AQIKLLQSAC NSYCMTPDQK FIQWFQRQQL LTEEESYALS CEIEAAADAS 

       550        560        570        580        590        600 
TTSPKPRKSM VKRLSLLFLG SDMITSPTPT KEQPKSTASG SSGESMDSVS VSSCESNHSE 

       610        620        630        640        650        660 
AEEGSITPMD TPDEPQKKLS ESSSSCSSIH SMDTNSSGMS SLINPLSSPP SCNNNPKIHK 

       670        680        690        700        710        720 
RSVSVTSITS TVLPPVYNQQ NEDTCIIRIS VEDNNGNMYK SIMLTSQDKT PAVIQRAMLK 

       730        740        750        760        770        780 
HNLDSDPAEE YELVQVISED KELVIPDSAN VFYAMNSQVN FDFILRKKNS MEEQVKLRSR 

       790        800 
TSLTLPRTAK RGCWSNRHSK ITL 

« Hide

References

[1]Ansorge W., Krieger S., Regiert T., Rittmueller C., Schwager B., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S.
Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Human endometrium carcinoma cell line EMBL CAD97658.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX537416 mRNA. Translation: CAD97658.1.
UniGeneHs.497148.

3D structure databases

ProteinModelPortalQ7Z3U6.
SMRQ7Z3U6. Positions 682-769.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ7Z3U6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG005864.

Family and domain databases

Gene3D1.10.840.10. 2 hits.
InterProIPR000159. Ras-assoc.
IPR000651. Ras-like_Gua-exchang_fac_N.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR023578. Ras_GEF_dom.
IPR001895. RasGRF_CDC25.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamPF00788. RA. 1 hit.
PF00617. RasGEF. 1 hit.
PF00618. RasGEF_N. 1 hit.
[Graphical view]
SMARTSM00314. RA. 1 hit.
SM00147. RasGEF. 1 hit.
SM00229. RasGEFN. 1 hit.
[Graphical view]
SUPFAMSSF48366. SSF48366. 2 hits.
SSF54236. SSF54236. 1 hit.
PROSITEPS50200. RA. 1 hit.
PS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
PS50212. RASGEF_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ7Z3U6_HUMAN
AccessionPrimary (citable) accession number: Q7Z3U6
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: June 11, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.