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Protein

Mitogen-activated protein kinase

Gene

DKFZp686O0215

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiQ7Z3H5

Names & Taxonomyi

Protein namesi
Recommended name:
Mitogen-activated protein kinaseSAAS annotation (EC:2.7.11.24SAAS annotation)
Gene namesi
Name:DKFZp686O0215Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

PTM / Processingi

Proteomic databases

PeptideAtlasiQ7Z3H5
PRIDEiQ7Z3H5

Structurei

3D structure databases

ProteinModelPortaliQ7Z3H5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 274Protein kinaseInterPro annotationAdd BLAST274

Phylogenomic databases

eggNOGiKOG0660 Eukaryota
ENOG410XNY0 LUCA
HOVERGENiHBG014652

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR003527 MAP_kinase_CS
IPR008349 MAPK_ERK1/2
IPR000719 Prot_kinase_dom
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
PRINTSiPR01770 ERK1ERK2MAPK
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS01351 MAPK, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Fragment.

Q7Z3H5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SSAYDHVRKT RVAIKKISPF EHQTYCQRTL REIQILLRFR HENVIGIRDI
60 70 80 90 100
LRASTLEAMR DVYIVQDLME TDLYKLLKSQ QLSNDHICYF LYQILRGLKY
110 120 130 140 150
IHSANVLHRD LKPSNLLINT TCDLKICDFG LARIADPEHD HTGFLTEYVA
160 170 180 190 200
TRWYRAPEIM LNSKGYTKSI DIWSVGCILA EMLSNRPIFP GKHYLDQLNH
210 220 230 240 250
ILGILGSPSQ EDLNCIINMK ARNYLQSLPS KTKVAWAKLF PKSDSKALDL
260 270 280 290 300
LDRMLTFNPN KRITVEEALA HPYLEQYYDP TDEPVAEEPF TFAMELDDLP
310 320
KERLKELIFQ ETARFQPGVL EAP
Length:323
Mass (Da):37,501
Last modified:October 1, 2003 - v1
Checksum:i53D4EF00913948C1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX537897 mRNA Translation: CAD97888.1
UniGeneiHs.861

Similar proteinsi

Entry informationi

Entry nameiQ7Z3H5_HUMAN
AccessioniPrimary (citable) accession number: Q7Z3H5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: January 31, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.