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Protein

Mitogen-activated protein kinase

Gene

DKFZp686O0215

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiQ7Z3H5.

Names & Taxonomyi

Protein namesi
Recommended name:
Mitogen-activated protein kinaseSAAS annotation (EC:2.7.11.24SAAS annotation)
Gene namesi
Name:DKFZp686O0215Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

PaxDbiQ7Z3H5.
PeptideAtlasiQ7Z3H5.
PRIDEiQ7Z3H5.

Structurei

3D structure databases

ProteinModelPortaliQ7Z3H5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 274Protein kinaseInterPro annotationAdd BLAST274

Phylogenomic databases

eggNOGiKOG0660. Eukaryota.
ENOG410XNY0. LUCA.
HOVERGENiHBG014652.

Family and domain databases

InterProiView protein in InterPro
IPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR008349. MAPK_ERK1/2.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
PRINTSiPR01770. ERK1ERK2MAPK.
SMARTiView protein in SMART
SM00220. S_TKc. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS01351. MAPK. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q7Z3H5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SSAYDHVRKT RVAIKKISPF EHQTYCQRTL REIQILLRFR HENVIGIRDI
60 70 80 90 100
LRASTLEAMR DVYIVQDLME TDLYKLLKSQ QLSNDHICYF LYQILRGLKY
110 120 130 140 150
IHSANVLHRD LKPSNLLINT TCDLKICDFG LARIADPEHD HTGFLTEYVA
160 170 180 190 200
TRWYRAPEIM LNSKGYTKSI DIWSVGCILA EMLSNRPIFP GKHYLDQLNH
210 220 230 240 250
ILGILGSPSQ EDLNCIINMK ARNYLQSLPS KTKVAWAKLF PKSDSKALDL
260 270 280 290 300
LDRMLTFNPN KRITVEEALA HPYLEQYYDP TDEPVAEEPF TFAMELDDLP
310 320
KERLKELIFQ ETARFQPGVL EAP
Length:323
Mass (Da):37,501
Last modified:October 1, 2003 - v1
Checksum:i53D4EF00913948C1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX537897 mRNA. Translation: CAD97888.1.
UniGeneiHs.861.

Similar proteinsi

Entry informationi

Entry nameiQ7Z3H5_HUMAN
AccessioniPrimary (citable) accession number: Q7Z3H5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: August 30, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.