Q7Z3H5 (Q7Z3H5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein DKFZp686O0215 EMBL CAD97888.1

Gene names

Name:

DKFZp686O0215 EMBL CAD97888.1

Organism

Homo sapiens (Human) EMBL CAD97888.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	323 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. SAAS SAAS003527
Sequence similarities	Contains 1 protein kinase domain. SAAS SAAS003527

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS003527 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase SAAS SAAS003527 Transferase
Gene Ontology (GO)
Biological_process	MAPK cascade Inferred from electronic annotation. Source: GOC cartilage development Inferred from electronic annotation. Source: Compara lipopolysaccharide-mediated signaling pathway Inferred from electronic annotation. Source: Compara negative regulation of apolipoprotein binding Inferred from electronic annotation. Source: Compara organ morphogenesis Inferred from electronic annotation. Source: Compara regulation of sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: Compara response to DNA damage stimulus Inferred from electronic annotation. Source: Compara response to exogenous dsRNA Inferred from electronic annotation. Source: Compara sensory perception of pain Inferred from electronic annotation. Source: Compara transcription, DNA-dependent Inferred from electronic annotation. Source: Compara
Cellular_component	cytoplasm Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: Compara pseudopodium Inferred from electronic annotation. Source: Compara
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW MAP kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL CAD97888.1

Sequences

	Sequence		Length	Mass (Da)
	Q7Z3H5 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 53D4EF00913948C1	FASTA	323	37,501
	10 20 30 40 50 60 SSAYDHVRKT RVAIKKISPF EHQTYCQRTL REIQILLRFR HENVIGIRDI LRASTLEAMR 70 80 90 100 110 120 DVYIVQDLME TDLYKLLKSQ QLSNDHICYF LYQILRGLKY IHSANVLHRD LKPSNLLINT 130 140 150 160 170 180 TCDLKICDFG LARIADPEHD HTGFLTEYVA TRWYRAPEIM LNSKGYTKSI DIWSVGCILA 190 200 210 220 230 240 EMLSNRPIFP GKHYLDQLNH ILGILGSPSQ EDLNCIINMK ARNYLQSLPS KTKVAWAKLF 250 260 270 280 290 300 PKSDSKALDL LDRMLTFNPN KRITVEEALA HPYLEQYYDP TDEPVAEEPF TFAMELDDLP 310 320 KERLKELIFQ ETARFQPGVL EAP

References

[1]	Koehrer K., Beyer A., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S. Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Human cervix EMBL CAD97888.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX537897 mRNA. Translation: CAD97888.1.
IPI	IPI00018195.
UniGene	Hs.861.
3D structure databases
HSSP	HSSP built from PDB template 1OZ1 based on UniProtKB Q16539.
ProteinModelPortal	Q7Z3H5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7Z3H5.
Proteomic databases
PRIDE	Q7Z3H5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG014652.
Gene expression databases
ArrayExpress	Q7Z3H5.
Bgee	Q7Z3H5.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR003527. MAP_kinase_CS. IPR008349. MAPK_ERK1/2. IPR000719. Prot_kinase_cat_dom. IPR002290. Ser/Thr_dual-sp_kinase_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
PRINTS	PR01770. ERK1ERK2MAPK.
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS01351. MAPK. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7Z3H5_HUMAN

Accession

Primary (citable) accession number: Q7Z3H5

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2003
Last sequence update:	October 1, 2003
Last modified:	January 9, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.