Q7Z3H4 (SAMD7_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sterile alpha motif domain-containing protein 7
Short name=SAM domain-containing protein 7

Gene names

Name:

SAMD7

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	446 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 SAM (sterile alpha motif) domain.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 446	446	Sterile alpha motif domain-containing protein 7		PRO_0000263102
Regions
	Domain	327 – 392	66	SAM
Natural variations
	Natural variant	220	1	E → D. Corresponds to variant rs10513680 [ dbSNP | Ensembl ].		VAR_029586

Sequences

	Sequence		Length	Mass (Da)
	Q7Z3H4 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 798E09885F1A0C17	FASTA	446	49,112
	10 20 30 40 50 60 MAVNPLLTPT GQQTIPLIPS PFGPPTVDRD VLPSTVAPTD PRQFCVPSQF GSSVLPNTNM 70 80 90 100 110 120 ANVLSSRIYP GWGILPPESI KAVARRNEMI QRHHTARTEM EMYAIYQQRR MEKINPKGLA 130 140 150 160 170 180 GLGIPFLYGS SVPAAPAAYH GRSMLPAGDL HFHRSTLRNL QGNPMLAATA PHFEESWGQR 190 200 210 220 230 240 CRRLRKNTGN QKALDSDAES SKSQAEEKIL GQTHAVPYEE DHYAKDPDIE APSNQKSSET 250 260 270 280 290 300 NEKPTTALAN TCGELEPTHR KPWGSHTTTL KAKAWDDGKE EASEQIFATC DEKNGVCPPV 310 320 330 340 350 360 PRPSLPGTHA LVTIGGNLSL DEDIQKWTVD DVHSFIRSLP GCSDYAQVFK DHAIDGETLP 370 380 390 400 410 420 LLTEEHLRGT MGLKLGPALK IQSQVSQHVG SMFYKKTLSF PIRQAFDQPA DTSPLLDPNS 430 440 WSDTMNIFCP QDTIIPKGIE RGSMRN

References

[1]

"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed: 17974005] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Retina.

[2]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX537903 mRNA. Translation: CAD97889.1. BC117339 mRNA. Translation: AAI17340.1.
IPI	IPI00375770.
RefSeq	NP_872416.1. NM_182610.2.
UniGene	Hs.439922.
3D structure databases
HSSP	HSSP built from PDB template 1PK1 based on UniProtKB P39769.
ProteinModelPortal	Q7Z3H4.
SMR	Q7Z3H4. Positions 322-387.
ModBase	Search...
PTM databases
PhosphoSite	Q7Z3H4.
Polymorphism databases
DMDM	74713382.
Proteomic databases
PRIDE	Q7Z3H4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000335556; ENSP00000334668; ENSG00000187033. ENST00000428432; ENSP00000391299; ENSG00000187033.
GeneID	344658.
KEGG	hsa:344658.
UCSC	uc003fgd.1. human.
Organism-specific databases
CTD	344658.
GeneCards	GC03P169629.
H-InvDB	HIX0024340.
HGNC	HGNC:25394. SAMD7.
HPA	HPA044187.
neXtProt	NX_Q7Z3H4.
PharmGKB	PA134861212.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG17503.
GeneTree	ENSGT00550000074459.
HOGENOM	HBG713905.
HOVERGEN	HBG093934.
InParanoid	Q7Z3H4.
OMA	RTEMEMY.
OrthoDB	EOG4M91RR.
PhylomeDB	Q7Z3H4.
Gene expression databases
Bgee	Q7Z3H4.
CleanEx	HS_SAMD7.
Genevestigator	Q7Z3H4.
GermOnline	ENSG00000187033. Homo sapiens.
Family and domain databases
InterPro	IPR001660. SAM. IPR013761. SAM/pointed. IPR021129. SAM_type1. [Graphical view]
Gene3D	G3DSA:1.10.150.50. SAM_type. 1 hit.
Pfam	PF00536. SAM_1. 1 hit. [Graphical view]
SMART	SM00454. SAM. 1 hit. [Graphical view]
SUPFAM	SSF47769. SAM_homology. 1 hit.
PROSITE	PS50105. SAM_DOMAIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	98731.

Entry information

Entry name

SAMD7_HUMAN

Accession

Primary (citable) accession number: Q7Z3H4

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	October 1, 2003
Last modified:	January 25, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.