Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q7Z3F1

- GP155_HUMAN

UniProt

Q7Z3F1 - GP155_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Integral membrane protein GPR155

Gene

GPR155

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. cognition Source: UniProt
  2. intracellular signal transduction Source: InterPro
  3. transmembrane transport Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Integral membrane protein GPR155
Alternative name(s):
G-protein coupled receptor PGR22
Gene namesi
Name:GPR155
Synonyms:PGR22
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:22951. GPR155.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei39 – 5921HelicalSequence AnalysisAdd
BLAST
Transmembranei80 – 10021HelicalSequence AnalysisAdd
BLAST
Transmembranei105 – 12521HelicalSequence AnalysisAdd
BLAST
Transmembranei134 – 15421HelicalSequence AnalysisAdd
BLAST
Transmembranei168 – 18821HelicalSequence AnalysisAdd
BLAST
Transmembranei214 – 23421HelicalSequence AnalysisAdd
BLAST
Transmembranei244 – 26421HelicalSequence AnalysisAdd
BLAST
Transmembranei274 – 29421HelicalSequence AnalysisAdd
BLAST
Transmembranei316 – 33621HelicalSequence AnalysisAdd
BLAST
Transmembranei347 – 36721HelicalSequence AnalysisAdd
BLAST
Transmembranei382 – 40221HelicalSequence AnalysisAdd
BLAST
Transmembranei415 – 43521HelicalSequence AnalysisAdd
BLAST
Transmembranei439 – 45921HelicalSequence AnalysisAdd
BLAST
Transmembranei481 – 50121HelicalSequence AnalysisAdd
BLAST
Transmembranei521 – 54121HelicalSequence AnalysisAdd
BLAST
Transmembranei661 – 68121HelicalSequence AnalysisAdd
BLAST
Transmembranei692 – 71221HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. extracellular vesicular exosome Source: UniProt
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134943679.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 870870Integral membrane protein GPR155PRO_0000087551Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi9 – 91N-linked (GlcNAc...)Sequence Analysis
Glycosylationi15 – 151N-linked (GlcNAc...)Sequence Analysis
Glycosylationi29 – 291N-linked (GlcNAc...)Sequence Analysis
Glycosylationi198 – 1981N-linked (GlcNAc...)Sequence Analysis
Glycosylationi309 – 3091N-linked (GlcNAc...)Sequence Analysis
Glycosylationi381 – 3811N-linked (GlcNAc...)Sequence Analysis
Glycosylationi543 – 5431N-linked (GlcNAc...)Sequence Analysis
Glycosylationi612 – 6121N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ7Z3F1.
PaxDbiQ7Z3F1.
PRIDEiQ7Z3F1.

PTM databases

PhosphoSiteiQ7Z3F1.

Expressioni

Gene expression databases

BgeeiQ7Z3F1.
CleanExiHS_GPR155.
GenevestigatoriQ7Z3F1.

Organism-specific databases

HPAiHPA036159.

Interactioni

Protein-protein interaction databases

BioGridi127389. 1 interaction.
MINTiMINT-4726605.

Structurei

3D structure databases

ProteinModelPortaliQ7Z3F1.
SMRiQ7Z3F1. Positions 765-842.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini757 – 83579DEPPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi483 – 4864Poly-Ile

Sequence similaritiesi

Contains 1 DEP domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG85075.
GeneTreeiENSGT00390000004153.
HOVERGENiHBG057276.
InParanoidiQ7Z3F1.
OMAiLYVELQF.
OrthoDBiEOG7M3HZS.
PhylomeDBiQ7Z3F1.
TreeFamiTF324034.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR004776. Auxin_eff.
IPR000591. DEP_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00610. DEP. 1 hit.
PF03547. Mem_trans. 2 hits.
[Graphical view]
SMARTiSM00049. DEP. 1 hit.
[Graphical view]
PROSITEiPS50186. DEP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7Z3F1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNSNLPAENL TIAVNMTKTL PTAVTHGFNS TNDPPSMSIT RLFPALLECF
60 70 80 90 100
GIVLCGYIAG RANVITSTQA KGLGNFVSRF ALPALLFKNM VVLNFSNVDW
110 120 130 140 150
SFLYSILIAK ASVFFIVCVL TLLVASPDSR FSKAGLFPIF ATQSNDFALG
160 170 180 190 200
YPIVEALYQT TYPEYLQYIY LVAPISLMML NPIGFIFCEI QKWKDTQNAS
210 220 230 240 250
QNKIKIVGLG LLRVLQNPIV FMVFIGIAFN FILDRKVPVY VENFLDGLGN
260 270 280 290 300
SFSGSALFYL GLTMVGKIKR LKKSAFVVLI LLITAKLLVL PLLCREMVEL
310 320 330 340 350
LDKGDSVVNH TSLSNYAFLY GVFPVAPGVA IFATQFNMEV EIITSGMVIS
360 370 380 390 400
TFVSAPIMYV SAWLLTFPTM DPKPLAYAIQ NVSFDISIVS LISLIWSLAI
410 420 430 440 450
LLLSKKYKQL PHMLTTNLLI AQSIVCAGMM IWNFVKEKNF VGQILVFVLL
460 470 480 490 500
YSSLYSTYLW TGLLAISLFL LKKRERVQIP VGIIIISGWG IPALLVGVLL
510 520 530 540 550
ITGKHNGDSI DSAFFYGKEQ MITTAVTLFC SILIAGISLM CMNQTAQAGS
560 570 580 590 600
YEGFDQSQSH KVVEPGNTAF EESPAPVNEP ELFTSSIPET SCCSCSMGNG
610 620 630 640 650
ELHCPSIEPI ANTSTSEPVI PSFEKNNHCV SRCNSQSCIL AQEEEQYLQS
660 670 680 690 700
GDQQLTRHVL LCLLLIIGLF ANLSSCLWWL FNQEPGRLYV ELQFFCAVFN
710 720 730 740 750
FGQGFISFGI FGLDKHLIIL PFKRRLEFLW NNKDTAENRD SPVSEEIKMT
760 770 780 790 800
CQQFIHYHRD LCIRNIVKER RCGAKTSAGT FCGCDLVSWL IEVGLASDRG
810 820 830 840 850
EAVIYGDRLV QGGVIQHITN EYEFRDEYLF YRFLQKSPEQ SPPAINANTL
860 870
QQERYKEIEH SSPPSHSPKT
Length:870
Mass (Da):96,919
Last modified:June 21, 2005 - v2
Checksum:i91A6CFC79B669ACB
GO

Sequence cautioni

The sequence BAB71170.1 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti33 – 331D → G in BAC03609. (PubMed:14702039)Curated
Sequence conflicti194 – 1941K → E in AAH28730. (PubMed:15489334)Curated
Sequence conflicti260 – 2601L → H in BAB71170. (PubMed:14702039)Curated
Sequence conflicti460 – 4601W → R in CAD97915. (PubMed:17974005)Curated
Sequence conflicti517 – 5171G → A in CAH10683. (PubMed:17974005)Curated
Sequence conflicti550 – 5501S → G in AAH28730. (PubMed:15489334)Curated
Sequence conflicti638 – 6381C → R in CAD97915. (PubMed:17974005)Curated
Sequence conflicti674 – 6741S → Y in AAH28730. (PubMed:15489334)Curated
Sequence conflicti693 – 6931Q → R in CAH10683. (PubMed:17974005)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056381 mRNA. Translation: BAB71170.1. Different initiation.
AK091200 mRNA. Translation: BAC03609.1.
AK096665 mRNA. Translation: BAC04835.1.
AK315125 mRNA. Translation: BAG37579.1.
BX537947 mRNA. Translation: CAD97915.1.
AL834154 mRNA. Translation: CAH10683.1.
AC010894 Genomic DNA. Translation: AAY14707.1.
AC018470 Genomic DNA. Translation: AAY24218.1.
CH471058 Genomic DNA. Translation: EAX11137.1.
CH471058 Genomic DNA. Translation: EAX11138.1.
CH471058 Genomic DNA. Translation: EAX11139.1.
BC028730 mRNA. Translation: AAH28730.1.
BC035037 mRNA. Translation: AAH35037.1.
AY255528 mRNA. Translation: AAO85040.1.
CCDSiCCDS2259.1.
RefSeqiNP_001028217.1. NM_001033045.3.
NP_001253979.1. NM_001267050.1.
NP_001253980.1. NM_001267051.1.
NP_689742.4. NM_152529.6.
UniGeneiHs.516604.
Hs.741466.

Genome annotation databases

EnsembliENST00000295500; ENSP00000295500; ENSG00000163328.
ENST00000392551; ENSP00000376334; ENSG00000163328.
ENST00000392552; ENSP00000376335; ENSG00000163328.
GeneIDi151556.
KEGGihsa:151556.
UCSCiuc002uit.4. human.

Polymorphism databases

DMDMi68052330.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056381 mRNA. Translation: BAB71170.1 . Different initiation.
AK091200 mRNA. Translation: BAC03609.1 .
AK096665 mRNA. Translation: BAC04835.1 .
AK315125 mRNA. Translation: BAG37579.1 .
BX537947 mRNA. Translation: CAD97915.1 .
AL834154 mRNA. Translation: CAH10683.1 .
AC010894 Genomic DNA. Translation: AAY14707.1 .
AC018470 Genomic DNA. Translation: AAY24218.1 .
CH471058 Genomic DNA. Translation: EAX11137.1 .
CH471058 Genomic DNA. Translation: EAX11138.1 .
CH471058 Genomic DNA. Translation: EAX11139.1 .
BC028730 mRNA. Translation: AAH28730.1 .
BC035037 mRNA. Translation: AAH35037.1 .
AY255528 mRNA. Translation: AAO85040.1 .
CCDSi CCDS2259.1.
RefSeqi NP_001028217.1. NM_001033045.3.
NP_001253979.1. NM_001267050.1.
NP_001253980.1. NM_001267051.1.
NP_689742.4. NM_152529.6.
UniGenei Hs.516604.
Hs.741466.

3D structure databases

ProteinModelPortali Q7Z3F1.
SMRi Q7Z3F1. Positions 765-842.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 127389. 1 interaction.
MINTi MINT-4726605.

PTM databases

PhosphoSitei Q7Z3F1.

Polymorphism databases

DMDMi 68052330.

Proteomic databases

MaxQBi Q7Z3F1.
PaxDbi Q7Z3F1.
PRIDEi Q7Z3F1.

Protocols and materials databases

DNASUi 151556.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000295500 ; ENSP00000295500 ; ENSG00000163328 .
ENST00000392551 ; ENSP00000376334 ; ENSG00000163328 .
ENST00000392552 ; ENSP00000376335 ; ENSG00000163328 .
GeneIDi 151556.
KEGGi hsa:151556.
UCSCi uc002uit.4. human.

Organism-specific databases

CTDi 151556.
GeneCardsi GC02M175296.
HGNCi HGNC:22951. GPR155.
HPAi HPA036159.
neXtProti NX_Q7Z3F1.
PharmGKBi PA134943679.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG85075.
GeneTreei ENSGT00390000004153.
HOVERGENi HBG057276.
InParanoidi Q7Z3F1.
OMAi LYVELQF.
OrthoDBi EOG7M3HZS.
PhylomeDBi Q7Z3F1.
TreeFami TF324034.

Miscellaneous databases

GeneWikii GPR155.
GenomeRNAii 151556.
NextBioi 86726.
PROi Q7Z3F1.

Gene expression databases

Bgeei Q7Z3F1.
CleanExi HS_GPR155.
Genevestigatori Q7Z3F1.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR004776. Auxin_eff.
IPR000591. DEP_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00610. DEP. 1 hit.
PF03547. Mem_trans. 2 hits.
[Graphical view ]
SMARTi SM00049. DEP. 1 hit.
[Graphical view ]
PROSITEi PS50186. DEP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Tongue and Trachea.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Amygdala and Retina.
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.
  6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 533-675.

Entry informationi

Entry nameiGP155_HUMAN
AccessioniPrimary (citable) accession number: Q7Z3F1
Secondary accession number(s): B2RCI2
, D3DPE2, Q4G0Y6, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 21, 2005
Last sequence update: June 21, 2005
Last modified: October 29, 2014
This is version 100 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3