Q7Z3C6 (ATG9A_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Autophagy-related protein 9A

Alternative name(s):
APG9-like 1
mATG9

Gene names

Name:	ATG9A
Synonyms:	APG9L1

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	839 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Plays a role in autophagy. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H. Ref.8
Subunit structure	Interacts with SUPT20H. Ref.10
Subcellular location	Cytoplasmic vesicle › autophagosome membrane; Multi-pass membrane protein By similarity. Golgi apparatus › trans-Golgi network membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein Ref.8.
Sequence similarities	Belongs to the ATG9 family.
Sequence caution	The sequence BAB13882.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence BAB15246.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence BAB55119.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Ontologies

Keywords
Biological process	Autophagy Protein transport Transport
Cellular component	Cytoplasmic vesicle Endosome Golgi apparatus Membrane
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Transmembrane Transmembrane helix
PTM	Glycoprotein Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	autophagic vacuole assembly Inferred from mutant phenotype Ref.6. Source: MGI innate immune response Inferred from electronic annotation. Source: Compara protein localization to Golgi apparatus Inferred from electronic annotation. Source: Compara protein transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	Golgi apparatus Inferred from electronic annotation. Source: UniProtKB-SubCell autophagic vacuole membrane Inferred from electronic annotation. Source: UniProtKB-SubCell cytoplasmic vesicle Inferred from electronic annotation. Source: UniProtKB-KW integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW late endosome membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
TBK1	Q9UHD2	2	EBI-727146,EBI-356402

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q7Z3C6-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q7Z3C6-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-61: Missing.

Isoform 3 (identifier: Q7Z3C6-3)

The sequence of this isoform differs from the canonical sequence as follows:
     455-528: NAHRSQTRDE...CSFAQMDVRQ → VHFGRVAEPH...ADRGLSVPAS
     529-839: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 839	839	Autophagy-related protein 9A		PRO_0000119820
Regions
	Topological domain	1 – 66	66	Cytoplasmic By similarity
	Transmembrane	67 – 87	21	Helical; Potential
	Topological domain	88 – 131	44	Lumenal By similarity
	Transmembrane	132 – 152	21	Helical; Potential
	Topological domain	153 – 289	137	Cytoplasmic By similarity
	Transmembrane	290 – 310	21	Helical; Potential
	Topological domain	311 – 371	61	Lumenal By similarity
	Transmembrane	372 – 392	21	Helical; Potential
	Topological domain	393 – 400	8	Cytoplasmic By similarity
	Transmembrane	401 – 421	21	Helical; Potential
	Topological domain	422 – 473	52	Lumenal By similarity
	Transmembrane	474 – 494	21	Helical; Potential
	Topological domain	495 – 839	345	Cytoplasmic By similarity
Amino acid modifications
	Modified residue	18	1	Phosphoserine Ref.9
	Modified residue	656	1	Phosphoserine Ref.9
	Modified residue	735	1	Phosphoserine Ref.12
	Modified residue	738	1	Phosphoserine Ref.12
	Modified residue	741	1	Phosphoserine Ref.12
	Modified residue	828	1	Phosphoserine Ref.7 Ref.11
	Glycosylation	99	1	N-linked (GlcNAc...) Ref.8
Natural variations
	Alternative sequence	1 – 61	61	Missing in isoform 2.		VSP_013396
	Alternative sequence	455 – 528	74	NAHRS…MDVRQ → VHFGRVAEPHCHTPHPHLLP APTGPGDYRLLPKLHRGGRW CGRYLLLCSDGCSPAWSSPV AICWADRGLSVPAS in isoform 3.		VSP_013397
	Alternative sequence	529 – 839	311	Missing in isoform 3.		VSP_013398
	Natural variant	592	1	S → G. Ref.1 Ref.5 Corresponds to variant rs2276635 [ dbSNP | Ensembl ].		VAR_021835
	Natural variant	659	1	Q → H. Corresponds to variant rs2276634 [ dbSNP | Ensembl ].		VAR_055534
Experimental info
	Sequence conflict	39	1	H → R in CAD97944. Ref.1
	Sequence conflict	300	1	L → P in CAD97944. Ref.1
	Sequence conflict	381	1	A → T in AAH65534. Ref.4
	Sequence conflict	519	1	C → R in CAD98061. Ref.1
	Sequence conflict	567	1	W → R in CAD98061. Ref.1
	Sequence conflict	669	1	H → N in BAB15246. Ref.5
	Sequence conflict	765	1	A → V in CAD97944. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 18, 2010. Version 3. Checksum: 69BE087CA550DC42	FASTA	839	94,447
	10 20 30 40 50 60 MAQFDTEYQR LEASYSDSPP GEEDLLVHVA EGSKSPWHHI ENLDLFFSRV YNLHQKNGFT 70 80 90 100 110 120 CMLIGEIFEL MQFLFVVAFT TFLVSCVDYD ILFANKMVNH SLHPTEPVKV TLPDAFLPAQ 130 140 150 160 170 180 VCSARIQENG SLITILVIAG VFWIHRLIKF IYNICCYWEI HSFYLHALRI PMSALPYCTW 190 200 210 220 230 240 QEVQARIVQT QKEHQICIHK RELTELDIYH RILRFQNYMV ALVNKSLLPL RFRLPGLGEA 250 260 270 280 290 300 VFFTRGLKYN FELILFWGPG SLFLNEWSLK AEYKRGGQRL ELAQRLSNRI LWIGIANFLL 310 320 330 340 350 360 CPLILIWQIL YAFFSYAEVL KREPGALGAR CWSLYGRCYL RHFNELEHEL QSRLNRGYKP 370 380 390 400 410 420 ASKYMNCFLS PLLTLLAKNG AFFAGSILAV LIALTIYDED VLAVEHVLTT VTLLGVTVTV 430 440 450 460 470 480 CRSFIPDQHM VFCPEQLLRV ILAHIHYMPD HWQGNAHRSQ TRDEFAQLFQ YKAVFILEEL 490 500 510 520 530 540 LSPIVTPLIL IFCLRPRALE IIDFFRNFTV EVVGVGDTCS FAQMDVRQHG HPQWLSAGQT 550 560 570 580 590 600 EASVYQQAED GKTELSLMHF AITNPGWQPP RESTAFLGFL KEQVQRDGAA ASLAQGGLLP 610 620 630 640 650 660 ENALFTSIQS LQSESEPLSL IANVVAGSSC RGPPLPRDLQ GSRHRAEVAS ALRSFSPLQP 670 680 690 700 710 720 GQAPTGRAHS TMTGSGVDAR TASSGSSVWE GQLQSLVLSE YASTEMSLHA LYMHQLHKQQ 730 740 750 760 770 780 AQAEPERHVW HRRESDESGE SAPDEGGEGA RAPQSIPRSA SYPCAAPRPG APETTALHGG 790 800 810 820 830 FQRRYGGITD PGTVPRVPSH FSRLPLGGWA EDGQSASRHP EPVPEEGSED ELPPQVHKV
	Isoform 2 [UniParc]. Checksum: DBF1B239460D7250	FASTA	778	87,379
	10 20 30 40 50 60 MLIGEIFELM QFLFVVAFTT FLVSCVDYDI LFANKMVNHS LHPTEPVKVT LPDAFLPAQV 70 80 90 100 110 120 CSARIQENGS LITILVIAGV FWIHRLIKFI YNICCYWEIH SFYLHALRIP MSALPYCTWQ 130 140 150 160 170 180 EVQARIVQTQ KEHQICIHKR ELTELDIYHR ILRFQNYMVA LVNKSLLPLR FRLPGLGEAV 190 200 210 220 230 240 FFTRGLKYNF ELILFWGPGS LFLNEWSLKA EYKRGGQRLE LAQRLSNRIL WIGIANFLLC 250 260 270 280 290 300 PLILIWQILY AFFSYAEVLK REPGALGARC WSLYGRCYLR HFNELEHELQ SRLNRGYKPA 310 320 330 340 350 360 SKYMNCFLSP LLTLLAKNGA FFAGSILAVL IALTIYDEDV LAVEHVLTTV TLLGVTVTVC 370 380 390 400 410 420 RSFIPDQHMV FCPEQLLRVI LAHIHYMPDH WQGNAHRSQT RDEFAQLFQY KAVFILEELL 430 440 450 460 470 480 SPIVTPLILI FCLRPRALEI IDFFRNFTVE VVGVGDTCSF AQMDVRQHGH PQWLSAGQTE 490 500 510 520 530 540 ASVYQQAEDG KTELSLMHFA ITNPGWQPPR ESTAFLGFLK EQVQRDGAAA SLAQGGLLPE 550 560 570 580 590 600 NALFTSIQSL QSESEPLSLI ANVVAGSSCR GPPLPRDLQG SRHRAEVASA LRSFSPLQPG 610 620 630 640 650 660 QAPTGRAHST MTGSGVDART ASSGSSVWEG QLQSLVLSEY ASTEMSLHAL YMHQLHKQQA 670 680 690 700 710 720 QAEPERHVWH RRESDESGES APDEGGEGAR APQSIPRSAS YPCAAPRPGA PETTALHGGF 730 740 750 760 770 QRRYGGITDP GTVPRVPSHF SRLPLGGWAE DGQSASRHPE PVPEEGSEDE LPPQVHKV
	Isoform 3 [UniParc]. Checksum: FB9BEBBFA794B352	FASTA	528	60,694
	10 20 30 40 50 60 MAQFDTEYQR LEASYSDSPP GEEDLLVHVA EGSKSPWHHI ENLDLFFSRV YNLHQKNGFT 70 80 90 100 110 120 CMLIGEIFEL MQFLFVVAFT TFLVSCVDYD ILFANKMVNH SLHPTEPVKV TLPDAFLPAQ 130 140 150 160 170 180 VCSARIQENG SLITILVIAG VFWIHRLIKF IYNICCYWEI HSFYLHALRI PMSALPYCTW 190 200 210 220 230 240 QEVQARIVQT QKEHQICIHK RELTELDIYH RILRFQNYMV ALVNKSLLPL RFRLPGLGEA 250 260 270 280 290 300 VFFTRGLKYN FELILFWGPG SLFLNEWSLK AEYKRGGQRL ELAQRLSNRI LWIGIANFLL 310 320 330 340 350 360 CPLILIWQIL YAFFSYAEVL KREPGALGAR CWSLYGRCYL RHFNELEHEL QSRLNRGYKP 370 380 390 400 410 420 ASKYMNCFLS PLLTLLAKNG AFFAGSILAV LIALTIYDED VLAVEHVLTT VTLLGVTVTV 430 440 450 460 470 480 CRSFIPDQHM VFCPEQLLRV ILAHIHYMPD HWQGVHFGRV AEPHCHTPHP HLLPAPTGPG 490 500 510 520 DYRLLPKLHR GGRWCGRYLL LCSDGCSPAW SSPVAICWAD RGLSVPAS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANT GLY-592. Tissue: Fetal brain, Lung endothelial cell, Rectum tumor and Testis.
[2]	"Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K. Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). Tissue: Brain and Lymph.
[5]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 156-839, VARIANT GLY-592. Tissue: Embryo.
[6]	"Endothelial nitric-oxide synthase antisense (NOS3AS) gene encodes an autophagy-related protein (APG9-like2) highly expressed in trophoblast." Yamada T., Carson A.R., Caniggia I., Umebayashi K., Yoshimori T., Nakabayashi K., Scherer S.W. J. Biol. Chem. 280:18283-18290(2005) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION.
[7]	"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M. Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-828, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[8]	"Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes." Young A.R., Chan E.Y., Hu X.W., Kochl R., Crawshaw S.G., High S., Hailey D.W., Lippincott-Schwartz J., Tooze S.A. J. Cell Sci. 119:3888-3900(2006) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION, TOPOLOGY, GLYCOSYLATION AT ASN-99.
[9]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-18 AND SER-656, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[10]	"Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP." Webber J.L., Tooze S.A. EMBO J. 29:27-40(2010) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH SUPT20H.
[11]	"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M. Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-828, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[12]	"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation." Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B. Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-735; SER-738 AND SER-741, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL833865 mRNA. Translation: CAD38723.1. BX537984 mRNA. Translation: CAD97944.1. BX538192 mRNA. Translation: CAD98061.1. BX538198 mRNA. Translation: CAD98064.1. AC068946 Genomic DNA. No translation available. CH471063 Genomic DNA. Translation: EAW70706.1. BC001098 mRNA. Translation: AAH01098.2. BC021202 mRNA. Translation: AAH21202.2. BC065534 mRNA. Translation: AAH65534.1. AK021732 mRNA. Translation: BAB13882.1. Different initiation. AK027448 mRNA. Translation: BAB55119.1. Different initiation. AK025822 mRNA. Translation: BAB15246.1. Different initiation. BK004018 mRNA. Translation: DAA05199.1.
IPI	IPI00383396. IPI00439694. IPI00555659.
RefSeq	NP_001070666.1. NM_001077198.1. NP_076990.4. NM_024085.3.
UniGene	Hs.323363.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q7Z3C6. 2 interactions.
MINT	MINT-1422125.
PTM databases
PhosphoSite	Q7Z3C6.
Polymorphism databases
DMDM	296439428.
Proteomic databases
PaxDb	Q7Z3C6.
PRIDE	Q7Z3C6.
Protocols and materials databases
DNASU	79065.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000361242; ENSP00000355173; ENSG00000198925. ENST00000396761; ENSP00000379983; ENSG00000198925. ENST00000409033; ENSP00000386482; ENSG00000198925. ENST00000409422; ENSP00000386535; ENSG00000198925. ENST00000409618; ENSP00000386710; ENSG00000198925.
GeneID	79065.
KEGG	hsa:79065.
UCSC	uc002vke.1. human.
Organism-specific databases
CTD	79065.
GeneCards	GC02M220074.
H-InvDB	HIX0002853. HIX0077803.
HGNC	HGNC:22408. ATG9A.
MIM	612204. gene.
neXtProt	NX_Q7Z3C6.
PharmGKB	PA134931318.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG298729.
HOVERGEN	HBG050539.
InParanoid	Q7Z3C6.
OMA	LMQFLFV.
OrthoDB	EOG4PNXGD.
Gene expression databases
ArrayExpress	Q7Z3C6.
Bgee	Q7Z3C6.
CleanEx	HS_ATG9A.
Genevestigator	Q7Z3C6.
GermOnline	ENSG00000198925. Homo sapiens.
Family and domain databases
InterPro	IPR007241. Autophagy-rel_prot_9. [Graphical view]
PANTHER	PTHR13038. PTHR13038. 1 hit.
Pfam	PF04109. APG9. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	79065.
NextBio	67835.
SOURCE	Search...

Entry information

Entry name

ATG9A_HUMAN

Accession

Primary (citable) accession number: Q7Z3C6
Secondary accession number(s): Q3ZAQ6 , Q6P0N7, Q7Z317, Q7Z320, Q8NDK6, Q8WU65, Q9BVL5, Q9H6L1, Q9HAG7

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 12, 2005
Last sequence update:	May 18, 2010
Last modified:	May 1, 2013
This is version 91 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.