Q7Z3A3 (Q7Z3A3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein DKFZp686M216 EMBL CAD97972.1

Gene names

Name:

DKFZp686M216 EMBL CAD97972.1

Organism

Homo sapiens (Human) EMBL CAD97972.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	566 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 PAC (PAS-associated C-terminal) domain. Contains 1 bHLH (basic helix-loop-helix) domain. SAAS SAAS000014 Contains 2 PAS (PER-ARNT-SIM) domains. SAAS SAAS000014

Ontologies

Keywords
Biological process	Transcription Transcription regulation SAAS SAAS000014
Cellular component	Nucleus SAAS SAAS000014
Domain	Repeat SAAS SAAS000014
Ligand	DNA-binding SAAS SAAS000014
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro transcription factor complex Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro signal transducer activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7Z3A3 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 1AD757636C51F4AA	FASTA	566	62,381
	10 20 30 40 50 60 MATPAAVNPP EMASDIPGSV TLPVAPMAAT GQVRMAGAMP ARGGKRRSGM DFDDEDGEGP 70 80 90 100 110 120 SKFSRENHSE IERRRRNKMT QYITELSDMV PTCSALARKP DKLTILRMAV SHMKSMRGTG 130 140 150 160 170 180 NKSTDGAYKP SFLTEQELKH LILEAADGFL FVVAAETGRV IYVSDSVTPV LNQPQSEWFG 190 200 210 220 230 240 STLYEQVHPD DVEKLREQLC TSENSMTGRI LDLKTGTVKK EGQQSSMRMC MGSRRSFICR 250 260 270 280 290 300 MRCGNAPLDH LPLNRITTMR KRFRNGLGPV KEGEAQYAVV HCTGYIKAWP PAGMTIPEED 310 320 330 340 350 360 ADVGQGSKYC LVAIGRLQVT SSPVCMDMNG MSVPTEFLSR HNSDGIITFV DPRCISVIGY 370 380 390 400 410 420 QPQDLLGKDI LEFCHPEDQS HLRESFQQVV KLKGQVLSVM YRFRTKNREW MLIRTSSFTF 430 440 450 460 470 480 QNPYSDEIEY IICTNTNVKQ LQQQQAELEV HQRDGLSSYD LSQVPVPNLP AGVHEAGKSV 490 500 510 520 530 540 EKADAIFSQE RDPRFAEMFA GISASEKKMM SSASAAGTQQ IYSQGSPFPS GHSGKAFSSS 550 560 VVHVPGVNDI QSSSSTGQNM SQISGS

References

[1]	Ansorge W., Krieger S., Regiert T., Rittmueller C., Schwager B., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S. Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Human cervix EMBL CAD97972.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX538026 mRNA. Translation: CAD97972.1.
IPI	IPI01015076.
RefSeq	NP_055677.3. NM_014862.3.
UniGene	Hs.459070.
3D structure databases
HSSP	HSSP built from PDB template 1P97 based on UniProtKB Q99814.
ProteinModelPortal	Q7Z3A3.
SMR	Q7Z3A3. Positions 62-118, 146-447.
ModBase	Search...
Protocols and materials databases
DNASU	9915.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	9915.
KEGG	hsa:9915.
Organism-specific databases
CTD	9915.
PharmGKB	PA24995.
Phylogenomic databases
HOVERGEN	HBG000164.
KO	K15589.
Family and domain databases
Gene3D	4.10.280.10. 1 hit.
InterPro	IPR011598. bHLH_dom. IPR001067. Nuc_translocat. IPR001610. PAC. IPR000014. PAS. IPR013767. PAS_fold. IPR013655. PAS_fold_3. [Graphical view]
Pfam	PF00010. HLH. 1 hit. PF00989. PAS. 1 hit. PF08447. PAS_3. 1 hit. [Graphical view]
PRINTS	PR00785. NCTRNSLOCATR.
SMART	SM00353. HLH. 1 hit. SM00086. PAC. 1 hit. SM00091. PAS. 2 hits. [Graphical view]
SUPFAM	SSF47459. HLH_basic. 1 hit.
TIGRFAMs	TIGR00229. sensory_box. 1 hit.
PROSITE	PS50888. BHLH. 1 hit. PS50112. PAS. 2 hits. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	9915.
NextBio	37404.

Entry information

Entry name

Q7Z3A3_HUMAN

Accession

Primary (citable) accession number: Q7Z3A3

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2003
Last sequence update:	October 1, 2003
Last modified:	May 1, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.