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Protein

Putative protein ZNF720

Gene

ZNF720

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Despite its name, it does not contain a canonical C2H2-type zinc-finger.Curated

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Putative protein ZNF720
Gene namesi
Name:ZNF720
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000197302.10
HGNCiHGNC:26987 ZNF720
neXtProtiNX_Q7Z2F6

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000197302
PharmGKBiPA143485683

Polymorphism and mutation databases

BioMutaiZNF720
DMDMi74738650

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003302931 – 126Putative protein ZNF720Add BLAST126

Proteomic databases

PaxDbiQ7Z2F6
PeptideAtlasiQ7Z2F6
PRIDEiQ7Z2F6

PTM databases

iPTMnetiQ7Z2F6
PhosphoSitePlusiQ7Z2F6

Expressioni

Gene expression databases

BgeeiENSG00000197302
CleanExiHS_ZNF720
ExpressionAtlasiQ7Z2F6 baseline and differential
GenevisibleiQ7Z2F6 HS

Organism-specific databases

HPAiHPA041570

Interactioni

Protein-protein interaction databases

BioGridi1258642 interactors.
IntActiQ7Z2F6 5 interactors.
STRINGi9606.ENSP00000319222

Structurei

3D structure databases

ProteinModelPortaliQ7Z2F6
SMRiQ7Z2F6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 75KRABPROSITE-ProRule annotationAdd BLAST72

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00910000144150
HOGENOMiHOG000231475
HOVERGENiHBG067759
InParanoidiQ7Z2F6
OrthoDBiEOG091G0DYX
PhylomeDBiQ7Z2F6
TreeFamiTF340491

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SUPFAMiSSF109640 SSF109640, 1 hit
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q7Z2F6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MGLLTFRDVA IEFSREEWEH LDSDQKLLYG DVMLENYGNL VSLGLAVSKP
60 70 80 90 100
DLITFLEQRK EPWNVKSAET VAIQPDIFSH DTQGLLRKKL IEASFQKVIL
110 120
DGYGSCGPQN LNLRKEWESE GKIILW
Length:126
Mass (Da):14,454
Last modified:October 1, 2003 - v1
Checksum:iBF678E7D8AEF7DA3
GO
Isoform 2 (identifier: Q7Z2F6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-70: Missing.
     71-74: VAIQ → MVNV
     123-126: IILW → CEGHNGYYDG...SLLKVCFTNK

Note: No experimental confirmation available.
Show »
Length:178
Mass (Da):20,246
Checksum:i2A28FE8BC1ACB898
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0330241 – 70Missing in isoform 2. 1 PublicationAdd BLAST70
Alternative sequenceiVSP_03302571 – 74VAIQ → MVNV in isoform 2. 1 Publication4
Alternative sequenceiVSP_033026123 – 126IILW → CEGHNGYYDGHTKCKTTTYN KNLTVTGGQKHEKTQFMSVA FSKPCVSVSKCQHQFLKLTF SFKGNLDNPNSDLVHVSNNH LNQLKYRTGVNVQSNISEKE RFKNEEVISKYDQFDGSLLK VCFTNK in isoform 2. 1 Publication4

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK128671 mRNA No translation available.
CH471192 Genomic DNA Translation: EAW52108.1
BC018134 mRNA Translation: AAH18134.1
BC055408 mRNA Translation: AAH55408.1
CCDSiCCDS45473.1 [Q7Z2F6-1]
RefSeqiNP_001124385.1, NM_001130913.1
UniGeneiHs.528826

Genome annotation databases

EnsembliENST00000316491; ENSP00000319222; ENSG00000197302 [Q7Z2F6-1]
ENST00000398696; ENSP00000443758; ENSG00000197302 [Q7Z2F6-2]
GeneIDi124411
KEGGihsa:124411
UCSCiuc002ecn.5 human [Q7Z2F6-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiZN720_HUMAN
AccessioniPrimary (citable) accession number: Q7Z2F6
Secondary accession number(s): Q6ZQX1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: October 1, 2003
Last modified: February 28, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome