Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Neurotoxin BmP08

Gene
N/A
Organism
Mesobuthus martensii (Manchurian scorpion) (Buthus martensii)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Miscellaneous

Does not show any effect on Na+, Ca2+ currents, nor on voltage-gated and calcium-activated potassium channels.

Names & Taxonomyi

Protein namesi
Recommended name:
Neurotoxin BmP08
Alternative name(s):
Short-chain peptide BmKX
OrganismiMesobuthus martensii (Manchurian scorpion) (Buthus martensii)
Taxonomic identifieri34649 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaScorpionesButhidaButhoideaButhidaeMesobuthus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 231 PublicationAdd BLAST23
ChainiPRO_000003533824 – 54Neurotoxin BmP08Add BLAST31

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi30 ↔ 45
Disulfide bondi36 ↔ 50
Disulfide bondi39 ↔ 53

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Expressed by the venom gland.

Structurei

Secondary structure

155
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi29 – 32Combined sources4
Helixi33 – 36Combined sources4
Turni37 – 39Combined sources3
Beta strandi47 – 51Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1RJINMR-A24-54[»]
1WT8NMR-A24-54[»]
ProteinModelPortaliQ7Z0H4.
SMRiQ7Z0H4.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ7Z0H4.

Family & Domainsi

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR036574. Scorpion_toxin-like_sf.
SUPFAMiSSF57095. SSF57095. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q7Z0H4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIFFAVLVI LVLFSMLIWT AYGTPYPVNC KTDRDCVMCG LGISCKNGYC

QGCTR
Length:55
Mass (Da):6,145
Last modified:October 1, 2003 - v1
Checksum:i8B30D90904D6A39C
GO

Mass spectrometryi

Molecular mass is 3326 Da from positions 24 - 54. Determined by ESI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY125328 mRNA. Translation: AAM91031.1.
AY147404 Genomic DNA. Translation: AAN39841.1.

Similar proteinsi

Entry informationi

Entry nameiSCKI_MESMA
AccessioniPrimary (citable) accession number: Q7Z0H4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: October 1, 2003
Last modified: October 25, 2017
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references