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Protein

Myogenic factor 6

Gene

MYF6

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein, DNA-binding
Biological processDifferentiation, Myogenesis

Enzyme and pathway databases

ReactomeiR-BTA-375170 CDO in myogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Myogenic factor 6
Short name:
Myf-6
Alternative name(s):
Muscle-specific regulatory factor 4
Gene namesi
Name:MYF6
Synonyms:MRF4
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 5

Organism-specific databases

VGNCiVGNC:31793 MYF6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001273501 – 242Myogenic factor 6Add BLAST242

Proteomic databases

PaxDbiQ7YS80
PRIDEiQ7YS80

Expressioni

Gene expression databases

BgeeiENSBTAG00000014003

Interactioni

Subunit structurei

Efficient DNA binding requires dimerization with another bHLH protein Interacts with CSRP3.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000018607

Structurei

3D structure databases

ProteinModelPortaliQ7YS80
SMRiQ7YS80
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini93 – 144bHLHPROSITE-ProRule annotationAdd BLAST52

Phylogenomic databases

eggNOGiKOG3960 Eukaryota
ENOG4111SED LUCA
GeneTreeiENSGT00530000063004
HOGENOMiHOG000234799
HOVERGENiHBG006429
InParanoidiQ7YS80
KOiK18485
OMAiDQQDKMQ
OrthoDBiEOG091G0GKD
TreeFamiTF316344

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR002546 Basic
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
PfamiView protein in Pfam
PF01586 Basic, 1 hit
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00520 BASIC, 1 hit
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit

Sequencei

Sequence statusi: Complete.

Q7YS80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMMDLFETGS YFFYLDGENV TLQPLEVAEG SPLYPGSDGT LSPCQDQMPP
60 70 80 90 100
EAGSDSSGEE HVLAPPGLQP PHCPGQCLIW ACKTCKRKSA PTDRRKAATL
110 120 130 140 150
RERRRLKKIN EAFEALKRRT VANPNQRLPK VEILRSAINY IERLQDLLHR
160 170 180 190 200
LDQQDKMQEL GVDPFSYRPK QENLEGADFL RTCSSQWPSV SDHSRGLVIT
210 220 230 240
AKEGGTSIDS SASSSLRCLS SIVDSISSEE HKLPCVEEVV EK
Length:242
Mass (Da):26,976
Last modified:October 1, 2003 - v1
Checksum:i0359147B18071020
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB110601 mRNA Translation: BAC76804.1
BC142159 mRNA Translation: AAI42160.1
RefSeqiNP_861527.1, NM_181811.1
UniGeneiBt.22973

Genome annotation databases

EnsembliENSBTAT00000018607; ENSBTAP00000018607; ENSBTAG00000014003
GeneIDi281336
KEGGibta:281336

Similar proteinsi

Entry informationi

Entry nameiMYF6_BOVIN
AccessioniPrimary (citable) accession number: Q7YS80
Secondary accession number(s): A5PJL5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: October 1, 2003
Last modified: March 28, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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