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Protein

Arrestin-C

Gene

ARR3

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Sensory transduction, Vision

Names & Taxonomyi

Protein namesi
Recommended name:
Arrestin-C
Alternative name(s):
Cone arrestin
Short name:
cArr
Retinal cone arrestin-3
Gene namesi
Name:ARR3
OrganismiSus scrofa (Pig)
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 391391Arrestin-CPRO_0000250487Add
BLAST

Proteomic databases

PaxDbiQ7YS78.
PeptideAtlasiQ7YS78.

Expressioni

Gene expression databases

GenevisibleiQ7YS78. SS.

Interactioni

Subunit structurei

Interacts with CXCR4; the interaction is dependent on the C-terminal phosphorylation of CXCR4 and modulates the calcium ion mobilization activity of CXCR4.By similarity

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000013174.

Structurei

3D structure databases

ProteinModelPortaliQ7YS78.
SMRiQ7YS78. Positions 2-372.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the arrestin family.Curated

Phylogenomic databases

eggNOGiKOG3865. Eukaryota.
ENOG410XR0F. LUCA.
HOGENOMiHOG000231319.
HOVERGENiHBG002399.
InParanoidiQ7YS78.
KOiK13801.
OrthoDBiEOG79W954.
TreeFamiTF314260.

Family and domain databases

Gene3Di2.60.40.640. 1 hit.
2.60.40.840. 1 hit.
InterProiIPR033042. ARR3.
IPR000698. Arrestin.
IPR011021. Arrestin-like_N.
IPR014752. Arrestin_C.
IPR011022. Arrestin_C-like.
IPR017864. Arrestin_CS.
IPR014753. Arrestin_N.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR11792. PTHR11792. 1 hit.
PTHR11792:SF19. PTHR11792:SF19. 1 hit.
PfamiPF02752. Arrestin_C. 1 hit.
PF00339. Arrestin_N. 1 hit.
[Graphical view]
PRINTSiPR00309. ARRESTIN.
SMARTiSM01017. Arrestin_C. 1 hit.
[Graphical view]
SUPFAMiSSF81296. SSF81296. 2 hits.
PROSITEiPS00295. ARRESTINS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7YS78-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRVFKKTCS NGKLSIYLGK RDFVDHVDMV EPIDGVVLVD PEYLKGRKMF
60 70 80 90 100
VMLTCAFRYG HDDLDVIGLT FRKDLYVQVQ QVVPAEPTSP QVPLTVLQER
110 120 130 140 150
LLHKLGDNAY PFNLQMVVNL PCSVTLQPGP DDTGKACGID FEVKSFCAEN
160 170 180 190 200
LEEKVSKKDS VRLVIRKIQF APVEPGPGPW AQTVRRFLLS AQPLQLQAWM
210 220 230 240 250
DREVHYHGKP ISVNVSINNS TNKVIKKIKI SVDQITDVVL YSLDKYTKTV
260 270 280 290 300
FIQEFTETIA ANSTFSKSFE VTPLLADNCE KQGLALDGKL KHGDTNLASS
310 320 330 340 350
TILRPGMDKE LLGILVSYKV RVNLMVSCGG ILGDLTASDV GVELPLILMH
360 370 380 390
PKPSNEAASS EDIVIEEFAR QEPGGREESQ EALAAEGDEG S
Length:391
Mass (Da):43,239
Last modified:October 3, 2006 - v2
Checksum:i25A5EAAE37684A55
GO

Sequence cautioni

The sequence CAD92082.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ564496 mRNA. Translation: CAD92082.1. Different initiation.
RefSeqiNP_999510.1. NM_214345.1.
UniGeneiSsc.17336.

Genome annotation databases

GeneIDi397622.
KEGGissc:397622.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ564496 mRNA. Translation: CAD92082.1. Different initiation.
RefSeqiNP_999510.1. NM_214345.1.
UniGeneiSsc.17336.

3D structure databases

ProteinModelPortaliQ7YS78.
SMRiQ7YS78. Positions 2-372.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000013174.

Proteomic databases

PaxDbiQ7YS78.
PeptideAtlasiQ7YS78.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi397622.
KEGGissc:397622.

Organism-specific databases

CTDi407.

Phylogenomic databases

eggNOGiKOG3865. Eukaryota.
ENOG410XR0F. LUCA.
HOGENOMiHOG000231319.
HOVERGENiHBG002399.
InParanoidiQ7YS78.
KOiK13801.
OrthoDBiEOG79W954.
TreeFamiTF314260.

Gene expression databases

GenevisibleiQ7YS78. SS.

Family and domain databases

Gene3Di2.60.40.640. 1 hit.
2.60.40.840. 1 hit.
InterProiIPR033042. ARR3.
IPR000698. Arrestin.
IPR011021. Arrestin-like_N.
IPR014752. Arrestin_C.
IPR011022. Arrestin_C-like.
IPR017864. Arrestin_CS.
IPR014753. Arrestin_N.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR11792. PTHR11792. 1 hit.
PTHR11792:SF19. PTHR11792:SF19. 1 hit.
PfamiPF02752. Arrestin_C. 1 hit.
PF00339. Arrestin_N. 1 hit.
[Graphical view]
PRINTSiPR00309. ARRESTIN.
SMARTiSM01017. Arrestin_C. 1 hit.
[Graphical view]
SUPFAMiSSF81296. SSF81296. 2 hits.
PROSITEiPS00295. ARRESTINS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Purification of mammalian cone photoreceptors by lectin panning and the enhancement of their survival in glia-conditioned medium."
    Balse E., Tessier L.H., Fuchs C., Forster V., Sahel J.A., Picaud S.
    Invest. Ophthalmol. Vis. Sci. 46:367-374(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Retina.

Entry informationi

Entry nameiARRC_PIG
AccessioniPrimary (citable) accession number: Q7YS78
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: October 3, 2006
Last modified: July 6, 2016
This is version 62 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.