Reviewed, UniProtKB/Swiss-Prot Q7YJS9 (NU1C_CALFG)

Names and origin

Protein names

Recommended name:
    NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic
    EC=1.6.5.-
Alternative name(s):
    NAD(P)H dehydrogenase subunit 1
      Short name=NDH subunit 1
    NADH-plastoquinone oxidoreductase subunit 1

Gene names

Name:

ndhA

Encoded on

Plastid; Chloroplast

Organism

Calycanthus floridus var. glaucus (Eastern sweetshrub) (Calycanthus fertilis var. ferax)

Taxonomic identifier

212734 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › magnoliids › Laurales › Calycanthaceae › Calycanthus

Protein attributes

Sequence length	363 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient By similarity.
Catalytic activity	NAD(P)H + plastoquinone = NAD(P)+ + plastoquinol. HAMAP MF_01350
Subunit structure	NDH is composed of at least 16 different subunits, 5 of which are encoded in the nucleus By similarity.
Subcellular location	Plastid › chloroplast thylakoid membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the complex I subunit 1 family.

Ontologies

Keywords
Cellular component	Chloroplast Membrane Plastid Thylakoid
Domain	Transmembrane
Ligand	NAD NADP Plastoquinone
Molecular function	Oxidoreductase
PTM	Quinone
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: HAMAP
Cellular component	chloroplast thylakoid membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW quinone binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 363	363	NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic HAMAP MF_01350		PRO_0000240016
Regions
	Transmembrane	28 – 48	21	Potential
	Transmembrane	98 – 118	21	Potential
	Transmembrane	127 – 147	21	Potential
	Transmembrane	248 – 268	21	Potential
	Transmembrane	303 – 323	21	Potential
	Transmembrane	343 – 363	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q7YJS9-1 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 87219804F0B40AD8	FASTA	363	40,156
	10 20 30 40 50 60 MIIDTTEVQA INSFSRSESL KEVYDLLWLL VPIFTPVLGI TIGVLVIVWL EREISAGIQQ 70 80 90 100 110 120 RIGPEYAGPL GILQALADGT KLLFKEDLLP SRGDIRLFSI GPSIAVISIL LSYSVIPFGY 130 140 150 160 170 180 RLVLADLGIG VFLWIAISSI APIGLLMSGY GSNNKYSFSG GLRAAAQSIS YEIPLTPCVL 190 200 210 220 230 240 SISLLSNSSS TVDIVEAQSK YGFWGWNLWR QPIGFIVFLI SSLAECERLP FDLPEAEEEL 250 260 270 280 290 300 VAGYQTEYSG IKFGLFYVAS YLNLLVSSLF VTVLYLGGWN LPIPYIFIPE PFGINKTDGV 310 320 330 340 350 360 FGTTIDILIT LAKSYLFLFV PIITRWTLPR MRMDQLLNLG WKFLLPISLG NLLLITSFQL VSL

References

[1]	"The chloroplast genome of the 'basal' angiosperm Calycanthus fertilis -- structural and phylogenetic analyses." Goremykin V., Hirsch-Ernst K.I., Woelfl S., Hellwig F.H. Plant Syst. Evol. 242:119-135(2003) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ428413 Genomic DNA. Translation: CAD28777.1.
RefSeq	NP_862810.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2597984.
Family and domain databases
HAMAP	MF_01350. [Tree]
InterPro	IPR001694. NADH_UbQ_OxRdtase_su1. IPR018086. NADH_UbQ_OxRdtase_su1_CS. [Graphical view]
PANTHER	PTHR11432. Resp_NADH_DH_1. 1 hit.
Pfam	PF00146. NADHdh. 1 hit. [Graphical view]
PROSITE	PS00667. COMPLEX1_ND1_1. 1 hit. PS00668. COMPLEX1_ND1_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NU1C_CALFG

Accession

Primary (citable) accession number: Q7YJS9

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 13, 2006
Last sequence update:	October 1, 2003
Last modified:	June 16, 2009
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)