Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Mannan endo-1,4-beta-mannosidase 2

Gene

MAN2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei215Proton donorBy similarity1
Active sitei335NucleophileBy similarity1

GO - Molecular functioni

  • mannan endo-1,4-beta-mannosidase activity Source: TAIR

GO - Biological processi

  • mannan catabolic process Source: GO_Central
  • mannan metabolic process Source: TAIR

Keywordsi

Molecular functionGlycosidase, Hydrolase

Enzyme and pathway databases

BioCyciARA:AT2G20680-MONOMER

Protein family/group databases

CAZyiGH5 Glycoside Hydrolase Family 5

Names & Taxonomyi

Protein namesi
Recommended name:
Mannan endo-1,4-beta-mannosidase 2 (EC:3.2.1.78)
Alternative name(s):
Beta-mannanase 2
Endo-beta-1,4-mannanase 2
Short name:
AtMAN2
Gene namesi
Name:MAN2
Ordered Locus Names:At2g20680
ORF Names:F5H14.35
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G20680
TAIRilocus:2051399 AT2G20680

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_000027747529 – 433Mannan endo-1,4-beta-mannosidase 2Add BLAST405

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi46N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi169N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ7Y223

Expressioni

Tissue specificityi

Expressed in roots, stems, leaves and seeds.1 Publication

Gene expression databases

ExpressionAtlasiQ7Y223 baseline and differential
GenevisibleiQ7Y223 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G20680.1

Structurei

3D structure databases

ProteinModelPortaliQ7Y223
SMRiQ7Y223
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IKPI Eukaryota
COG3934 LUCA
HOGENOMiHOG000169952
InParanoidiQ7Y223
KOiK19355
OMAiWITAHVE
OrthoDBiEOG09360BHK
PhylomeDBiQ7Y223

Family and domain databases

InterProiView protein in InterPro
IPR001547 Glyco_hydro_5
IPR017853 Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF00150 Cellulase, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q7Y223-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAPTGNGPV IPILGFLTCV AFIYLSFGDL WFGLKTEGEL AFVKRNGTQF
60 70 80 90 100
VVDGKALYVN GWNSYWFMDH AVNDHSRHRV SAMLEAGAKM GLTVCRTWAF
110 120 130 140 150
NDGGYNALQI SPGRFDERVF KALDHVIAEA KTHGVRLLLS LVNNLQAYGG
160 170 180 190 200
KTQYVNWAWQ EGVGLSSSND SFFFDPSIRR YFKNYLTVLL TRKNSLTGIE
210 220 230 240 250
YRNDPTIFAW ELINEPRCMS DVSGDTLQDW INEMTAFIKS IDNKHLLTVG
260 270 280 290 300
LEGFYGPSSP KKLTVNPERW ASELGSDFVR NSDSPNIDFA SVHIYPDHWF
310 320 330 340 350
HDQGFEEKLK FVVKWMLSHI EDGDKELKKP VLFTEFGLSN LNKDYDPSQR
360 370 380 390 400
DRFYRTIFDV IYKSAKRKRS GAGTLVWQFL IEGMEGFNDD FGIVPWEQDS
410 420 430
IQRLMIEQSC RLSRITGRHL LDKKSIEMCS HRP
Length:433
Mass (Da):49,558
Last modified:October 1, 2003 - v1
Checksum:iDBC5FEBE6749B2D3
GO

Sequence cautioni

The sequence AAD20927 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006234 Genomic DNA Translation: AAD20927.1 Sequence problems.
CP002685 Genomic DNA Translation: AEC07056.1
BT008596 mRNA Translation: AAP40422.1
BT025988 mRNA Translation: ABG25077.1
AK228569 mRNA Translation: BAF00487.1
PIRiA84592
RefSeqiNP_179660.2, NM_127632.3
UniGeneiAt.39660

Genome annotation databases

EnsemblPlantsiAT2G20680.1; AT2G20680.1; AT2G20680
GeneIDi816596
GrameneiAT2G20680.1; AT2G20680.1; AT2G20680
KEGGiath:AT2G20680

Similar proteinsi

Entry informationi

Entry nameiMAN2_ARATH
AccessioniPrimary (citable) accession number: Q7Y223
Secondary accession number(s): Q9SKU9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: October 1, 2003
Last modified: April 25, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health