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Protein

Histone deacetylase 3

Gene

HDAC3

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.By similarity

Miscellaneous

Plants silencing HDAC3 exhibit reduced peduncle elongation and fertility.1 Publication

Catalytic activityi

Hydrolysis of an N6-acetyl-lysine residue of a histone to yield a deacetylated histone.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei158By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulator, Hydrolase, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

ReactomeiR-OSA-1538133. G0 and Early G1.

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylase 31 Publication (EC:3.5.1.98By similarity)
Short name:
OsHDAC31 Publication
Gene namesi
Name:HDAC31 Publication
Synonyms:HDA7031 Publication
Ordered Locus Names:Os02g0214900Imported, LOC_Os02g12350Curated
ORF Names:OJ1006_D05.27-1Imported
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 2

Subcellular locationi

  • Nucleus By similarity

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004405621 – 510Histone deacetylase 3Add BLAST510

Expressioni

Tissue specificityi

Expressed in roots.1 Publication

Inductioni

Induced by drought and salt stresses.1 Publication

Gene expression databases

ExpressionAtlasiQ7Y0Y6. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os02g12350.1.

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni24 – 338Histone deacetylaseCuratedAdd BLAST315

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1342. Eukaryota.
COG0123. LUCA.
KOiK06067.
OMAiKCVEFVR.
OrthoDBiEOG093609CH.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiView protein in InterPro
IPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiView protein in Pfam
PF00850. Hist_deacetyl. 1 hit.
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.

Sequencei

Sequence statusi: Complete.

Q7Y0Y6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPSSAGAGG NSLASASCGD AQKRRVCYFY DPEVGNYYYG QGHPMKPHRV
60 70 80 90 100
RMTHALLAHY GLLAPAKMEV LRPLPARGID LCRFHSDDYV AFLRAVTPET
110 120 130 140 150
QLGQVRALRR FNIGPDCPVF DGLYAYCQTY AGASVGAAVK LNHGTHDIAI
160 170 180 190 200
NWSGGLHHAK KSEASGFCYV NDIVLAILEL LKLHERVLYI DIDIHHGDGV
210 220 230 240 250
EEAFYTTNRV MTVSFHKFGD YFPGTGDIRD IGYSEGKYYC LNVPLDDGID
260 270 280 290 300
DDSYQSIFKP IISKVMEMYR PGAVVLQCGA DSLSGDRLGC FNLSGKGHAE
310 320 330 340 350
CVKFMRSFNV PLLLLGGGGY TIRNVARCWC YETGVALGEE LQEKLPYNEY
360 370 380 390 400
YEYFGPEYSL YVAASNMENR NTNKQLEEIK CNILDNLSKL QHAPSVQFQE
410 420 430 440 450
RIPETKLPEP DEDQEDPDER HDPDSDMVLD DHKPTGHSAR SLIHNIGVKR
460 470 480 490 500
EITETETKDQ HGKRLTTEHK GPEPMAEDLG SSKQAPTADA NAVAVNAPGN
510
ARNEPGSSPK
Length:510
Mass (Da):56,504
Last modified:October 1, 2003 - v1
Checksum:i664090CF78C12535
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF513384 mRNA. Translation: AAP47173.1.
AP004039 Genomic DNA. Translation: BAD25048.1.
AP008208 Genomic DNA. Translation: BAF08198.1.
AP014958 Genomic DNA. Translation: BAS77624.1.
RefSeqiXP_015623652.1. XM_015768166.1.
UniGeneiOs.79864.

Genome annotation databases

EnsemblPlantsiOS02T0214900-01; OS02T0214900-01; OS02G0214900.
GeneIDi4328717.
GrameneiOS02T0214900-01; OS02T0214900-01; OS02G0214900.
KEGGiosa:4328717.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiHDAC3_ORYSJ
AccessioniPrimary (citable) accession number: Q7Y0Y6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2017
Last sequence update: October 1, 2003
Last modified: July 5, 2017
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families