Reviewed, UniProtKB/Swiss-Prot Q7XV13 (LOX5_ORYSJ)

Names and origin

Protein names

Recommended name:
    Putative lipoxygenase 5
    EC=1.13.11.12

Gene names

Ordered Locus Names:	Os04g0447100, LOC_Os04g37430
ORF Names:	OSJNBa0064H22.1

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	899 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Catalyzes the hydroperoxidation of lipids, containing a cis,cis-1,4-pentadiene structure By similarity.
Catalytic activity	Linoleate + O2 = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate.
Cofactor	Binds 1 iron ion per subunit. Iron is tightly bound By similarity.
Pathway	Lipid metabolism; oxylipin biosynthesis.
Sequence similarities	Belongs to the lipoxygenase family. Contains 1 lipoxygenase domain. Contains 1 PLAT domain.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Lipid synthesis Oxylipin biosynthesis
Ligand	Iron Metal-binding
Molecular function	Dioxygenase Oxidoreductase
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW oxylipin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW lipoxygenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 899	899	Putative lipoxygenase 5		PRO_0000220711
Regions
	Domain	68 – 204	137	PLAT
	Domain	207 – 899	693	Lipoxygenase
Sites
	Metal binding	559	1	Iron; catalytic By similarity
	Metal binding	564	1	Iron; catalytic By similarity
	Metal binding	751	1	Iron; catalytic By similarity
	Metal binding	755	1	Iron; catalytic By similarity
	Metal binding	899	1	Iron; via carboxylate; catalytic By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7XV13-1 [UniParc]. Last modified March 1, 2004. Version 2. Checksum: 02FDC5545BBAE928	FASTA	899	100,082
	10 20 30 40 50 60 MRGGAGMCFA SMEAAGSRGM GKGASRRRTA RSTAPVGALV ERVVVAPAPV EQQRGAGRPE 70 80 90 100 110 120 AHPQSVAARA VVTVRRRRKE DAKDRFAEQL DALADRVGRS VLLELVSTET DPRKGTPKKS 130 140 150 160 170 180 KPSALVGWFD KKDVKAERVV YTAEFAVDAG FGEPGAVTVL NRHQREFYIE SIVVEGFPTG 190 200 210 220 230 240 PAHFTCNSWV QPTRVSRDRR VFFSNRPYLP SETPPGLREL RLRELADLRG DGTGERRITD 250 260 270 280 290 300 RVYDYDVYND LGNPDKGVAS ARPVLGGEQM PYPRRMRTGR PSTATDASAE SRVEYPEPIY 310 320 330 340 350 360 VSRDEEFEEG KNEMLSEGAI KALLHNFMPL LVSSVSPDIR DFAGFHDVDN LFKEGLRLKQ 370 380 390 400 410 420 ALHDQLFQKI PFVRKIQENS EGLLRYDTPD IIKKDKFAWL RDDEFARQAL AGINPVNIER 430 440 450 460 470 480 LQAFPPVSKL DPAVYGPPES AITEEHIIGH LDGMSVQEAV EGSRLYMLDY HDIFLPFLDR 490 500 510 520 530 540 INAQDGRKAY GTRAVFFLTA AGTLKPIAIE LCLPPMTDGC KRAKRVFTPP ADATSNWLWQ 550 560 570 580 590 600 LAKAHVCSND AGVHQLINHW LRTHACMEPF IIAAHRQMSA MHPIFKLLKP HMRYTLKINA 610 620 630 640 650 660 LARQILINGD GVIESGFTPG NVCMEMSAFA YRELWRLDQE GLPADLIRRG MAVEDPSQPH 670 680 690 700 710 720 GLRLLIEDYP YAADGLLLWS AISRWCEAYV AAYYPSDEAV QADYELQSWY AEAVQSGHAD 730 740 750 760 770 780 KRGAPWWPRL STPGDLASLL TTLVWLCSAQ HAALNFGQYP LGGYIPNRPP LMRRLVPAEG 790 800 810 820 830 840 DPEYAHLVAD PHRFFLSALP SLTQTTTFMT VIDTLSTHSA DEEYLGERPD EAWTADPAAL 850 860 870 880 890 AAAREFAADV RRAEEEIERR NADPSRRNRC GAGVLPYELM APSSGPGITC RGVPNSVTI

References

[1]

"Sequence and analysis of rice chromosome 4." Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y., Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q., Zhang L. , Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T., Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R., Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G., Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C., Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J., Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J., Li J., Hong G., Xue Y., Han B. Nature 420:316-320(2002) [PubMed: 12447439] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL606448 Genomic DNA. Translation: CAD40882.2.
3D structure databases
SMR	Q7XV13. Positions 77-899.
ModBase	Search...
Organism-specific databases
Gramene	Q7XV13.
Family and domain databases
InterPro	IPR008976. Lipase_LipOase. IPR000907. LipOase. IPR013819. LipOase_C. IPR020834. LipOase_CS. IPR020833. LipOase_Fe_BS. IPR001024. LipOase_LH2. IPR001246. LipOase_pln. [Graphical view]
Gene3D	G3DSA:2.60.60.20. Lipase_LipOase. 1 hit.
PANTHER	PTHR11771. LipOase. 1 hit.
Pfam	PF00305. Lipoxygenase. 1 hit. PF01477. PLAT. 1 hit. [Graphical view]
PRINTS	PR00087. LIPOXYGENASE. PR00468. PLTLPOXGNASE.
SMART	SM00308. LH2. 1 hit. [Graphical view]
PROSITE	PS00711. LIPOXYGENASE_1. 1 hit. PS00081. LIPOXYGENASE_2. 1 hit. PS51393. LIPOXYGENASE_3. 1 hit. PS50095. PLAT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LOX5_ORYSJ

Accession

Primary (citable) accession number: Q7XV13

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	March 1, 2004
Last modified:	January 19, 2010
This is version 39 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)