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Protein

Putative lipoxygenase 5

Gene

Os04g0447100

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure (By similarity).By similarity

Catalytic activityi

Linoleate + O2 = (9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate.
Alpha-linolenate + O2 = (9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate.

Cofactori

Fe cationPROSITE-ProRule annotationNote: Binds 1 Fe cation per subunit. Iron is tightly bound.PROSITE-ProRule annotation

Pathway:ioxylipin biosynthesis

This protein is involved in the pathway oxylipin biosynthesis, which is part of Lipid metabolism.PROSITE-ProRule annotation
View all proteins of this organism that are known to be involved in the pathway oxylipin biosynthesis and in Lipid metabolism.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi559 – 5591Iron; catalyticPROSITE-ProRule annotation
Metal bindingi564 – 5641Iron; catalyticPROSITE-ProRule annotation
Metal bindingi751 – 7511Iron; catalyticPROSITE-ProRule annotation
Metal bindingi755 – 7551Iron; catalyticPROSITE-ProRule annotation
Metal bindingi899 – 8991Iron; via carboxylate; catalyticPROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Dioxygenase, Oxidoreductase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Oxylipin biosynthesis

Keywords - Ligandi

Iron, Metal-binding

Enzyme and pathway databases

ReactomeiREACT_283708. Synthesis of Lipoxins (LX).
REACT_285219. Synthesis of 15-eicosatetraenoic acid derivatives.
REACT_306592. Synthesis of Hepoxilins (HX) and Trioxilins (TrX).
REACT_347183. Synthesis of Leukotrienes (LT) and Eoxins (EX).
REACT_354994. Synthesis of 12-eicosatetraenoic acid derivatives.
UniPathwayiUPA00382.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative lipoxygenase 5 (EC:1.13.11.12)
Gene namesi
Ordered Locus Names:Os04g0447100, LOC_Os04g37430
ORF Names:OSJNBa0064H22.1
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
ProteomesiUP000000763 Componenti: Chromosome 4

Organism-specific databases

GrameneiQ7XV13.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 899899Putative lipoxygenase 5PRO_0000220711Add
BLAST

Expressioni

Gene expression databases

ExpressionAtlasiQ7XV13. baseline.

Structurei

3D structure databases

ProteinModelPortaliQ7XV13.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini68 – 204137PLATPROSITE-ProRule annotationAdd
BLAST
Domaini207 – 899693LipoxygenasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the lipoxygenase family.Curated
Contains 1 lipoxygenase domain.PROSITE-ProRule annotation
Contains 1 PLAT domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG69653.
InParanoidiQ7XV13.

Family and domain databases

Gene3Di2.60.60.20. 1 hit.
4.10.372.10. 1 hit.
InterProiIPR008976. Lipase_LipOase.
IPR000907. LipOase.
IPR013819. LipOase_C.
IPR020834. LipOase_CS.
IPR020833. LipOase_Fe_BS.
IPR001246. LipOase_plant.
IPR027433. Lipoxygenase_domain_3.
IPR001024. PLAT/LH2_dom.
[Graphical view]
PANTHERiPTHR11771. PTHR11771. 1 hit.
PfamiPF00305. Lipoxygenase. 1 hit.
PF01477. PLAT. 1 hit.
[Graphical view]
PRINTSiPR00087. LIPOXYGENASE.
PR00468. PLTLPOXGNASE.
SMARTiSM00308. LH2. 1 hit.
[Graphical view]
SUPFAMiSSF48484. SSF48484. 1 hit.
SSF49723. SSF49723. 1 hit.
PROSITEiPS00711. LIPOXYGENASE_1. 1 hit.
PS00081. LIPOXYGENASE_2. 1 hit.
PS51393. LIPOXYGENASE_3. 1 hit.
PS50095. PLAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7XV13-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGGAGMCFA SMEAAGSRGM GKGASRRRTA RSTAPVGALV ERVVVAPAPV
60 70 80 90 100
EQQRGAGRPE AHPQSVAARA VVTVRRRRKE DAKDRFAEQL DALADRVGRS
110 120 130 140 150
VLLELVSTET DPRKGTPKKS KPSALVGWFD KKDVKAERVV YTAEFAVDAG
160 170 180 190 200
FGEPGAVTVL NRHQREFYIE SIVVEGFPTG PAHFTCNSWV QPTRVSRDRR
210 220 230 240 250
VFFSNRPYLP SETPPGLREL RLRELADLRG DGTGERRITD RVYDYDVYND
260 270 280 290 300
LGNPDKGVAS ARPVLGGEQM PYPRRMRTGR PSTATDASAE SRVEYPEPIY
310 320 330 340 350
VSRDEEFEEG KNEMLSEGAI KALLHNFMPL LVSSVSPDIR DFAGFHDVDN
360 370 380 390 400
LFKEGLRLKQ ALHDQLFQKI PFVRKIQENS EGLLRYDTPD IIKKDKFAWL
410 420 430 440 450
RDDEFARQAL AGINPVNIER LQAFPPVSKL DPAVYGPPES AITEEHIIGH
460 470 480 490 500
LDGMSVQEAV EGSRLYMLDY HDIFLPFLDR INAQDGRKAY GTRAVFFLTA
510 520 530 540 550
AGTLKPIAIE LCLPPMTDGC KRAKRVFTPP ADATSNWLWQ LAKAHVCSND
560 570 580 590 600
AGVHQLINHW LRTHACMEPF IIAAHRQMSA MHPIFKLLKP HMRYTLKINA
610 620 630 640 650
LARQILINGD GVIESGFTPG NVCMEMSAFA YRELWRLDQE GLPADLIRRG
660 670 680 690 700
MAVEDPSQPH GLRLLIEDYP YAADGLLLWS AISRWCEAYV AAYYPSDEAV
710 720 730 740 750
QADYELQSWY AEAVQSGHAD KRGAPWWPRL STPGDLASLL TTLVWLCSAQ
760 770 780 790 800
HAALNFGQYP LGGYIPNRPP LMRRLVPAEG DPEYAHLVAD PHRFFLSALP
810 820 830 840 850
SLTQTTTFMT VIDTLSTHSA DEEYLGERPD EAWTADPAAL AAAREFAADV
860 870 880 890
RRAEEEIERR NADPSRRNRC GAGVLPYELM APSSGPGITC RGVPNSVTI
Length:899
Mass (Da):100,082
Last modified:March 1, 2004 - v2
Checksum:i02FDC5545BBAE928
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL606448 Genomic DNA. Translation: CAD40882.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL606448 Genomic DNA. Translation: CAD40882.2.

3D structure databases

ProteinModelPortaliQ7XV13.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

GrameneiQ7XV13.

Phylogenomic databases

eggNOGiNOG69653.
InParanoidiQ7XV13.

Enzyme and pathway databases

UniPathwayiUPA00382.
ReactomeiREACT_283708. Synthesis of Lipoxins (LX).
REACT_285219. Synthesis of 15-eicosatetraenoic acid derivatives.
REACT_306592. Synthesis of Hepoxilins (HX) and Trioxilins (TrX).
REACT_347183. Synthesis of Leukotrienes (LT) and Eoxins (EX).
REACT_354994. Synthesis of 12-eicosatetraenoic acid derivatives.

Gene expression databases

ExpressionAtlasiQ7XV13. baseline.

Family and domain databases

Gene3Di2.60.60.20. 1 hit.
4.10.372.10. 1 hit.
InterProiIPR008976. Lipase_LipOase.
IPR000907. LipOase.
IPR013819. LipOase_C.
IPR020834. LipOase_CS.
IPR020833. LipOase_Fe_BS.
IPR001246. LipOase_plant.
IPR027433. Lipoxygenase_domain_3.
IPR001024. PLAT/LH2_dom.
[Graphical view]
PANTHERiPTHR11771. PTHR11771. 1 hit.
PfamiPF00305. Lipoxygenase. 1 hit.
PF01477. PLAT. 1 hit.
[Graphical view]
PRINTSiPR00087. LIPOXYGENASE.
PR00468. PLTLPOXGNASE.
SMARTiSM00308. LH2. 1 hit.
[Graphical view]
SUPFAMiSSF48484. SSF48484. 1 hit.
SSF49723. SSF49723. 1 hit.
PROSITEiPS00711. LIPOXYGENASE_1. 1 hit.
PS00081. LIPOXYGENASE_2. 1 hit.
PS51393. LIPOXYGENASE_3. 1 hit.
PS50095. PLAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiLOX5_ORYSJ
AccessioniPrimary (citable) accession number: Q7XV13
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: March 1, 2004
Last modified: June 24, 2015
This is version 67 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.