Q7XUF4 (CDKG2_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cyclin-dependent kinase G-2
Short name=CDKG;2
EC=2.7.11.22
EC=2.7.11.23

Gene names

Name:	CDKG-2
Ordered Locus Names:	Os04g0488000, LOC_Os04g41100
ORF Names:	OJ991113_30.14

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	710 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.
Induction	Down-regulated by cytokinin. Ref.5
Sequence similarities	Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. Contains 1 protein kinase domain.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase Transferase
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell cycle Inferred from electronic annotation. Source: GOC
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW RNA polymerase II carboxy-terminal domain kinase activity Inferred from electronic annotation. Source: EC cyclin-dependent protein serine/threonine kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 710	710	Cyclin-dependent kinase G-2		PRO_0000296112
Regions
	Domain	365 – 656	292	Protein kinase
	Nucleotide binding	371 – 379	9	ATP By similarity
Sites
	Active site	489	1	Proton acceptor By similarity
	Binding site	394	1	ATP By similarity
Amino acid modifications
	Modified residue	375	1	Phosphothreonine By similarity
	Modified residue	376	1	Phosphotyrosine By similarity
	Modified residue	516	1	Phosphoserine By similarity
	Modified residue	522	1	Phosphothreonine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7XUF4 [UniParc]. Last modified March 1, 2004. Version 2. Checksum: C8A958D5DDA4EE91	FASTA	710	79,883
	10 20 30 40 50 60 MAAGRHGGYR DYEARERELD AEASRRSKEQ QHHHHPSGRH QRGDSDPRCE ADRRRDGGRS 70 80 90 100 110 120 RGGRELSNGY GHRRSPPPRS RLSARLGDRE PGEVLSGSAS DDSGGRPHRA RENGVSSSSR 130 140 150 160 170 180 DGESVVAASA SSPSKKRKFS PIIWDRDSPK PMHSDVAKGK KAVDSVPTEL PLPPPPPLPP 190 200 210 220 230 240 QDHIPERLAV EKSPMDVEPA VASESPEQLQ EHAESRVMEE EEEYSTMRNI STSRWAGAND 250 260 270 280 290 300 DEEEGAPHRK KKSASPADSA ELGQRKKALS PELGEVVASD ISGGRTMSRS SDSGRLGADE 310 320 330 340 350 360 NEDLEVDKDD YMDVDRDDDG NSDIANHQSG MDSEYEVRRS ETPEPVKPPH RCINMLQGCR 370 380 390 400 410 420 SVDEFERLNK INEGTYGVVY RARDKKTGEI VALKKVKMEK EREGFPLTSL REINILLSFH 430 440 450 460 470 480 HPSIVDVKEV VVGSSLDSIF MVMEYMEHDL KGVMEAMKQP YSQSEVKCLM LQLLEGVKYL 490 500 510 520 530 540 HDNWVLHRDL KTSNLLLNNR GELKICDFGL SRQYGSPLKP YTQLVVTLWY RAPELLLGTK 550 560 570 580 590 600 EYSTAIDMWS VGCIMAELLA KEPLFNGKTE FEQLDKIFRT LGTPNEKIWP GYAKLPGVKV 610 620 630 640 650 660 NFVKQPYNRL RDKFPAASFS GRPILSEAGF DLLNNLLTYD PEKRLSADAA LQHEWFREVP 670 680 690 700 710 LPKSKDFMPT FPALNELDRR TKRYLKSPDP LEEQRLKELQ GNIGNRGLFG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of rice chromosome 4." Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y., Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q., Zhang L. , Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T., Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R., Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G., Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C., Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J., Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J., Li J., Hong G., Xue Y., Han B. Nature 420:316-320(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[4]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
[5]	"Genome-wide identification and expression analysis of rice cell cycle genes." Guo J., Song J., Wang F., Zhang X.S. Plant Mol. Biol. 64:349-360(2007) [PubMed] [Europe PMC] [Abstract] Cited for: INDUCTION, GENE FAMILY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL662946 Genomic DNA. Translation: CAD41330.2. AP008210 Genomic DNA. Translation: BAF15061.1. AK111619 mRNA. No translation available.
RefSeq	NP_001053147.1. NM_001059682.1.
UniGene	Os.15587.
3D structure databases
HSSP	HSSP built from PDB template 1H00 based on UniProtKB P24941.
ProteinModelPortal	Q7XUF4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os04g41100.1; LOC_Os04g41100.1; LOC_Os04g41100. LOC_Os04g41100.2; LOC_Os04g41100.2; LOC_Os04g41100. LOC_Os04g41100.3; LOC_Os04g41100.3; LOC_Os04g41100. LOC_Os04g41100.4; LOC_Os04g41100.4; LOC_Os04g41100. LOC_Os04g41100.5; LOC_Os04g41100.5; LOC_Os04g41100.
GeneID	4336224.
KEGG	dosa:Os04t0488000-01. osa:4336224.
Organism-specific databases
Gramene	Q7XUF4.
Phylogenomic databases
eggNOG	COG0515.
KO	K08818.
OMA	VPTRNIS.
ProtClustDB	CLSN2692912.
Gene expression databases
ArrayExpress	Q7XUF4.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR002290. Ser/Thr_dual-sp_kinase_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. False negative. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CDKG2_ORYSJ

Accession

Primary (citable) accession number: Q7XUF4

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 24, 2007
Last sequence update:	March 1, 2004
Last modified:	May 1, 2013
This is version 77 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program