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Q7XUA6 (PIP23_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable aquaporin PIP2-3
Alternative name(s):
OsPIP2;3
Plasma membrane intrinsic protein 2-3
Gene names
Name:PIP2-3
Ordered Locus Names:Os04g0521100, LOC_Os04g44060
ORF Names:OSJNBa0019D11.16
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length290 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Aquaporins facilitate the transport of water and small neutral solutes across cell membranes By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Tissue specificity

Expressed in roots. Ref.4

Induction

Circadian-regulation. Expression is higher during the light phase than during the dark phase. Down-regulated by chilling. Ref.4

Domain

Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).

Sequence similarities

Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC 1.A.8.11) subfamily. [View classification]

Ontologies

Keywords
   Biological processTransport
   Cellular componentCell membrane
Membrane
   DomainRepeat
Transmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processresponse to water deprivation

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

water transport

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontransporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 290290Probable aquaporin PIP2-3
PRO_0000064036

Regions

Transmembrane43 – 6321Helical; Name=1; Potential
Transmembrane82 – 10221Helical; Name=2; Potential
Transmembrane131 – 15121Helical; Name=3; Potential
Transmembrane173 – 19321Helical; Name=4; Potential
Transmembrane207 – 22721Helical; Name=5; Potential
Transmembrane255 – 27521Helical; Name=6; Potential
Motif112 – 1143NPA 1
Motif233 – 2353NPA 2

Sequences

Sequence LengthMass (Da)Tools
Q7XUA6 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: D27EABEFB266D851

FASTA29030,416
        10         20         30         40         50         60 
MAKDIEAAAA AEGGEYMAKD YSDPPPAPLI DAEELTKWSL YRAVIAEFVA TLLFLYITVA 

        70         80         90        100        110        120 
TVIGYKHQSD PGANAADAAC SGVGILGIAW AFGGMIFILV YCTAGVSGGH INPAVTFGLF 

       130        140        150        160        170        180 
LARKVSLVRA VLYIVAQSLG AICGVGLVKG FQSAFYVRYG GGANELSDGY SKGTGLAAEI 

       190        200        210        220        230        240 
IGTFVLVYTV FSATDPKRNA RDSHVPVLAP LPIGFAVFMV HLATIPITGT GINPARSLGA 

       250        260        270        280        290 
AVIYNQHKAW HDHWIFWVGP LIGAAIAAAY HQYVLRASAA KLGSSSSFRG 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of rice chromosome 4."
Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y., Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q., Zhang L. expand/collapse author list , Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T., Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R., Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G., Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C., Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J., Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J., Li J., Hong G., Xue Y., Han B.
Nature 420:316-320(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[4]"Identification of 33 rice aquaporin genes and analysis of their expression and function."
Sakurai J., Ishikawa F., Yamaguchi T., Uemura M., Maeshima M.
Plant Cell Physiol. 46:1568-1577(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NOMENCLATURE, TISSUE SPECIFICITY, INDUCTION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL662958 Genomic DNA. Translation: CAD41442.1.
AP008210 Genomic DNA. Translation: BAF15249.1.
RefSeqNP_001053335.1. NM_001059870.2.
UniGeneOs.5916.

3D structure databases

ProteinModelPortalQ7XUA6.
SMRQ7XUA6. Positions 27-284.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING39947.LOC_Os04g44060.1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS04T0521100-01; OS04T0521100-01; OS04G0521100.
GeneID4336424.
KEGGosa:4336424.

Organism-specific databases

GrameneQ7XUA6.

Phylogenomic databases

eggNOGCOG0580.
HOGENOMHOG000288286.
KOK09872.
OMACRRENIM.
ProtClustDBCLSN2692959.

Family and domain databases

Gene3D1.20.1080.10. 1 hit.
InterProIPR023271. Aquaporin-like.
IPR000425. MIP.
IPR022357. MIP_CS.
[Graphical view]
PANTHERPTHR19139. PTHR19139. 1 hit.
PfamPF00230. MIP. 1 hit.
[Graphical view]
PRINTSPR00783. MINTRINSICP.
SUPFAMSSF81338. SSF81338. 1 hit.
TIGRFAMsTIGR00861. MIP. 1 hit.
PROSITEPS00221. MIP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePIP23_ORYSJ
AccessionPrimary (citable) accession number: Q7XUA6
Secondary accession number(s): Q0JBN8
Entry history
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: October 1, 2003
Last modified: April 16, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations