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Protein

Probable aquaporin PIP2-3

Gene

PIP2-3

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

ReactomeiREACT_314049. Erythrocytes take up oxygen and release carbon dioxide.
REACT_328809. Passive transport by Aquaporins.
REACT_329585. Erythrocytes take up carbon dioxide and release oxygen.
REACT_334329. Vasopressin regulates renal water homeostasis via Aquaporins.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable aquaporin PIP2-3
Alternative name(s):
OsPIP2;3
Plasma membrane intrinsic protein 2-3
Gene namesi
Name:PIP2-3
Ordered Locus Names:Os04g0521100, LOC_Os04g44060
ORF Names:OSJNBa0019D11.16
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
ProteomesiUP000000763 Componenti: Chromosome 4

Organism-specific databases

GrameneiQ7XUA6.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei43 – 6321Helical; Name=1Sequence AnalysisAdd
BLAST
Transmembranei82 – 10221Helical; Name=2Sequence AnalysisAdd
BLAST
Transmembranei131 – 15121Helical; Name=3Sequence AnalysisAdd
BLAST
Transmembranei173 – 19321Helical; Name=4Sequence AnalysisAdd
BLAST
Transmembranei207 – 22721Helical; Name=5Sequence AnalysisAdd
BLAST
Transmembranei255 – 27521Helical; Name=6Sequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 290290Probable aquaporin PIP2-3PRO_0000064036Add
BLAST

Expressioni

Tissue specificityi

Expressed in roots.1 Publication

Inductioni

Circadian-regulation. Expression is higher during the light phase than during the dark phase. Down-regulated by chilling.1 Publication

Gene expression databases

ExpressionAtlasiQ7XUA6. baseline.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os04g44060.1.

Structurei

3D structure databases

ProteinModelPortaliQ7XUA6.
SMRiQ7XUA6. Positions 27-284.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi112 – 1143NPA 1
Motifi233 – 2353NPA 2

Domaini

Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0580.
HOGENOMiHOG000288286.
InParanoidiQ7XUA6.
KOiK09872.
OMAiGMAFFIF.

Family and domain databases

Gene3Di1.20.1080.10. 1 hit.
InterProiIPR023271. Aquaporin-like.
IPR000425. MIP.
IPR022357. MIP_CS.
[Graphical view]
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiPF00230. MIP. 1 hit.
[Graphical view]
PRINTSiPR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.
TIGRFAMsiTIGR00861. MIP. 1 hit.
PROSITEiPS00221. MIP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7XUA6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKDIEAAAA AEGGEYMAKD YSDPPPAPLI DAEELTKWSL YRAVIAEFVA
60 70 80 90 100
TLLFLYITVA TVIGYKHQSD PGANAADAAC SGVGILGIAW AFGGMIFILV
110 120 130 140 150
YCTAGVSGGH INPAVTFGLF LARKVSLVRA VLYIVAQSLG AICGVGLVKG
160 170 180 190 200
FQSAFYVRYG GGANELSDGY SKGTGLAAEI IGTFVLVYTV FSATDPKRNA
210 220 230 240 250
RDSHVPVLAP LPIGFAVFMV HLATIPITGT GINPARSLGA AVIYNQHKAW
260 270 280 290
HDHWIFWVGP LIGAAIAAAY HQYVLRASAA KLGSSSSFRG
Length:290
Mass (Da):30,416
Last modified:October 1, 2003 - v1
Checksum:iD27EABEFB266D851
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662958 Genomic DNA. Translation: CAD41442.1.
AP008210 Genomic DNA. Translation: BAF15249.1.
RefSeqiNP_001053335.1. NM_001059870.2.
UniGeneiOs.5916.

Genome annotation databases

EnsemblPlantsiOS04T0521100-01; OS04T0521100-01; OS04G0521100.
GeneIDi4336424.
KEGGiosa:4336424.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662958 Genomic DNA. Translation: CAD41442.1.
AP008210 Genomic DNA. Translation: BAF15249.1.
RefSeqiNP_001053335.1. NM_001059870.2.
UniGeneiOs.5916.

3D structure databases

ProteinModelPortaliQ7XUA6.
SMRiQ7XUA6. Positions 27-284.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os04g44060.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS04T0521100-01; OS04T0521100-01; OS04G0521100.
GeneIDi4336424.
KEGGiosa:4336424.

Organism-specific databases

GrameneiQ7XUA6.

Phylogenomic databases

eggNOGiCOG0580.
HOGENOMiHOG000288286.
InParanoidiQ7XUA6.
KOiK09872.
OMAiGMAFFIF.

Enzyme and pathway databases

ReactomeiREACT_314049. Erythrocytes take up oxygen and release carbon dioxide.
REACT_328809. Passive transport by Aquaporins.
REACT_329585. Erythrocytes take up carbon dioxide and release oxygen.
REACT_334329. Vasopressin regulates renal water homeostasis via Aquaporins.

Gene expression databases

ExpressionAtlasiQ7XUA6. baseline.

Family and domain databases

Gene3Di1.20.1080.10. 1 hit.
InterProiIPR023271. Aquaporin-like.
IPR000425. MIP.
IPR022357. MIP_CS.
[Graphical view]
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiPF00230. MIP. 1 hit.
[Graphical view]
PRINTSiPR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.
TIGRFAMsiTIGR00861. MIP. 1 hit.
PROSITEiPS00221. MIP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  4. "Identification of 33 rice aquaporin genes and analysis of their expression and function."
    Sakurai J., Ishikawa F., Yamaguchi T., Uemura M., Maeshima M.
    Plant Cell Physiol. 46:1568-1577(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NOMENCLATURE, TISSUE SPECIFICITY, INDUCTION.

Entry informationi

Entry nameiPIP23_ORYSJ
AccessioniPrimary (citable) accession number: Q7XUA6
Secondary accession number(s): Q0JBN8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: October 1, 2003
Last modified: July 22, 2015
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.