Reviewed, UniProtKB/Swiss-Prot Q7XTV3 (WOX4_ORYSJ)

Names and origin

Protein names

Recommended name:
    WUSCHEL-related homeobox 4
Alternative name(s):
    OsWOX4

Gene names

Name:	WOX4
Synonyms:	HB3
Ordered Locus Names:	Os04g0649400, LOC_Os04g55590
ORF Names:	OSJNBa0010D21.16, OSJNBb0059K02.2, OsJ_015698

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	236 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Transcription factor which may be involved in developmental processes By similarity.
Subcellular location	NucleusBy similarity.
Sequence similarities	Belongs to the WUS homeobox family. Contains 1 homeobox DNA-binding domain.
Sequence caution	The sequence BAF15996.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAD88982.1 differs from that shown. Reason: Frameshift at position 169.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Domain	Homeobox
Ligand	DNA-binding
Molecular function	Developmental protein
Gene Ontology (GO)
Biological process	multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Cellular component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 236	236	WUSCHEL-related homeobox 4		PRO_0000308639
Regions
	DNA binding	88 – 152	65	Homeobox; WUS-type
Experimental info
	Sequence conflict	161	1	S → R in CAD88982. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q7XTV3-1 [UniParc]. Last modified March 1, 2004. Version 2. Checksum: 867C4F82E854D6E9	FASTA	236	25,783
	10 20 30 40 50 60 MRLHHLHVAY LDHKASSSSS SPAPPSISPS SIPGSAAFPA FSFKCLRPLA PKISLPEPRK 70 80 90 100 110 120 MIAPPDFVVP RARNASKLLN YTVQVPAAGT TRWNPSAEQI KVLEMLYRGG MRTPNSVQIE 130 140 150 160 170 180 RITEELGKYG RIEGKNVFYW FQNHKARERQ KQKRAALLTL STLDPSLLPA TANETKEAPE 190 200 210 220 230 KKEKDVEDGL ASCKRRCKAW GDGAGDGDAV VATEAAGGCT DEVTLELFPL HPQGKA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A new homeobox gene cloned from rice unmature embryo also has transcripts in pollen mother cell." Duan K. Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"Sequence and analysis of rice chromosome 4." Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y., Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q., Zhang L. , Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T., Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R., Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G., Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C., Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J., Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J., Li J., Hong G., Xue Y., Han B. Nature 420:316-320(2002) [PubMed: 12447439] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[4]	"Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana." The rice annotation project (RAP) Genome Res. 17:175-183(2007) [PubMed: 17210932] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[5]	"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed: 15685292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[6]	"The shoot stem cell niche in angiosperms: expression patterns of WUS orthologues in rice and maize imply major modifications in the course of mono- and dicot evolution." Nardmann J., Werr W. Mol. Biol. Evol. 23:2492-2504(2006) [PubMed: 16987950] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 88-152.
[7]	"A WUSCHEL-LIKE HOMEOBOX gene represses a YABBY gene expression required for rice leaf development." Dai M., Hu Y., Zhao Y., Liu H., Zhou D.-X. Plant Physiol. 144:380-390(2007) [PubMed: 17351053] [Abstract] Cited for: NOMENCLATURE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ556181 mRNA. Translation: CAD88982.1. Frameshift. AL606635 Genomic DNA. Translation: CAD41713.2. AL606692 Genomic DNA. Translation: CAE04492.1. AP008210 Genomic DNA. Translation: BAF15996.1. Sequence problems. CM000141 Genomic DNA. Translation: EAZ32215.1. AM234750 mRNA. Translation: CAJ84142.1.
RefSeq	NP_001054082.1.
UniGene	Os.49747
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4337218.
KEGG	osa:4337218.
Organism-specific databases
Gramene	Q7XTV3.
Family and domain databases
InterPro	IPR001356. Homeobox. [Graphical view]
Pfam	PF00046. Homeobox. 1 hit. [Graphical view]
SMART	SM00389. HOX. 1 hit. [Graphical view]
PROSITE	PS00027. HOMEOBOX_1. False negative. PS50071. HOMEOBOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

WOX4_ORYSJ

Accession

Primary (citable) accession number: Q7XTV3
Secondary accession number(s): A0AAT1 , Q0J9J1, Q70Q05, Q7X7F6

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 23, 2007
Last sequence update:	March 1, 2004
Last modified:	November 25, 2008
This is version 50 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)