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Q7XTC7 (P2C40_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase 2C 40

Short name=OsPP2C40
EC=3.1.3.16
Gene names
Ordered Locus Names:Os04g0449400, LOC_Os04g37660
ORF Names:OSJNBa0064H22.20
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length461 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Sequence caution

The sequence BAF14845.2 differs from that shown. Reason: Erroneous gene model prediction.

The sequence CAE01570.2 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Coding sequence diversityAlternative splicing
   LigandMagnesium
Manganese
Metal-binding
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q7XTC7-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q7XTC7-2)

The sequence of this isoform differs from the canonical sequence as follows:
     384-392: LDSEYPVRN → FVLCTLYPS
     393-461: Missing.
Note: Derived from EST data. No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 461461Probable protein phosphatase 2C 40
PRO_0000363287

Regions

Domain56 – 314259PP2C-like
Compositional bias2 – 87Poly-Ala

Sites

Metal binding981Manganese 1 By similarity
Metal binding981Manganese 2 By similarity
Metal binding991Manganese 1; via carbonyl oxygen By similarity
Metal binding2731Manganese 2 By similarity
Metal binding3121Manganese 2 By similarity

Natural variations

Alternative sequence384 – 3929LDSEYPVRN → FVLCTLYPS in isoform 2.
VSP_036267
Alternative sequence393 – 46169Missing in isoform 2.
VSP_036268

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified February 10, 2009. Version 3.
Checksum: FB7D3035F093C1BA

FASTA46148,707
        10         20         30         40         50         60 
MAAAAAAATV EAVGVAGGRR RRSGSVALGD LLRREASAER ASASASAGAG GRERERRPSV 

        70         80         90        100        110        120 
AAGQACRAKK GEDFALLKPA CERLPAGGAP FSAFALFDGH NGSGAAVYAK ENILSNVMCC 

       130        140        150        160        170        180 
VPADLSGDEW LAALPRALVA GFVKTDKDFQ TRAHSSGTTV TFVIIDGYVV TVASVGDSRC 

       190        200        210        220        230        240 
VLEAEGTIYH LSADHRFDAS EEEVGRVTEC GGEVGRLNVV GGAEIGPLRC WPGGLCLSRS 

       250        260        270        280        290        300 
IGDQDVGEFI IPVPYVKQIK LSSAGGRIII SSDGVWDALT VDTAFSCARG LPPEAAADQI 

       310        320        330        340        350        360 
VKEAIASKGL RDDTTCIVID IIPPEKISPT VQPAKKAGKG LFKNIFYKKA TSDSPCHADK 

       370        380        390        400        410        420 
DQCTQPDLVE EVFEDGCPSL SRRLDSEYPV RNMFKLFICA ICQVELESGQ GISIHEGLSK 

       430        440        450        460 
SGKLRPWDGP FLCHSCQEKK EAMEGKRHSR DSSSRNSGSS E 

« Hide

Isoform 2 [UniParc].

Checksum: ED423DB5E4E2C3A4
Show »

FASTA39241,019

References

« Hide 'large scale' references
[1]"Sequence and analysis of rice chromosome 4."
Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y., Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q., Zhang L. expand/collapse author list , Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T., Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R., Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G., Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C., Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J., Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J., Li J., Hong G., Xue Y., Han B.
Nature 420:316-320(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[4]"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL606448 Genomic DNA. Translation: CAE01570.2. Sequence problems.
AP008210 Genomic DNA. Translation: BAF14845.2. Sequence problems.
RefSeqNP_001052931.2. NM_001059466.2.
UniGeneOs.7326.

3D structure databases

ProteinModelPortalQ7XTC7.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4335989.
KEGGosa:4335989.

Organism-specific databases

GrameneQ7XTC7.

Phylogenomic databases

eggNOGCOG0631.
HOGENOMHOG000240114.
OMADFQTRAH.

Family and domain databases

Gene3D3.60.40.10. 1 hit.
InterProIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 1 hit.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 1 hit.
ProtoNetSearch...

Entry information

Entry nameP2C40_ORYSJ
AccessionPrimary (citable) accession number: Q7XTC7
Secondary accession number(s): Q0JCU2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: February 10, 2009
Last modified: May 14, 2014
This is version 61 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations