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Q7XTC7

- P2C40_ORYSJ

UniProt

Q7XTC7 - P2C40_ORYSJ

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Protein
Probable protein phosphatase 2C 40
Gene
Os04g0449400, LOC_Os04g37660, OSJNBa0064H22.20
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 magnesium or manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi98 – 981Manganese 1 By similarity
Metal bindingi98 – 981Manganese 2 By similarity
Metal bindingi99 – 991Manganese 1; via carbonyl oxygen By similarity
Metal bindingi273 – 2731Manganese 2 By similarity
Metal bindingi312 – 3121Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 40 (EC:3.1.3.16)
Short name:
OsPP2C40
Gene namesi
Ordered Locus Names:Os04g0449400, LOC_Os04g37660
ORF Names:OSJNBa0064H22.20
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 4

Organism-specific databases

GrameneiQ7XTC7.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 461461Probable protein phosphatase 2C 40
PRO_0000363287Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ7XTC7.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini56 – 314259PP2C-like
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi2 – 87Poly-Ala

Sequence similaritiesi

Belongs to the PP2C family.
Contains 1 PP2C-like domain.

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000240114.
OMAiDFQTRAH.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q7XTC7-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MAAAAAAATV EAVGVAGGRR RRSGSVALGD LLRREASAER ASASASAGAG    50
GRERERRPSV AAGQACRAKK GEDFALLKPA CERLPAGGAP FSAFALFDGH 100
NGSGAAVYAK ENILSNVMCC VPADLSGDEW LAALPRALVA GFVKTDKDFQ 150
TRAHSSGTTV TFVIIDGYVV TVASVGDSRC VLEAEGTIYH LSADHRFDAS 200
EEEVGRVTEC GGEVGRLNVV GGAEIGPLRC WPGGLCLSRS IGDQDVGEFI 250
IPVPYVKQIK LSSAGGRIII SSDGVWDALT VDTAFSCARG LPPEAAADQI 300
VKEAIASKGL RDDTTCIVID IIPPEKISPT VQPAKKAGKG LFKNIFYKKA 350
TSDSPCHADK DQCTQPDLVE EVFEDGCPSL SRRLDSEYPV RNMFKLFICA 400
ICQVELESGQ GISIHEGLSK SGKLRPWDGP FLCHSCQEKK EAMEGKRHSR 450
DSSSRNSGSS E 461
Length:461
Mass (Da):48,707
Last modified:February 10, 2009 - v3
Checksum:iFB7D3035F093C1BA
GO
Isoform 2 (identifier: Q7XTC7-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     384-392: LDSEYPVRN → FVLCTLYPS
     393-461: Missing.

Note: Derived from EST data. No experimental confirmation available.

Show »
Length:392
Mass (Da):41,019
Checksum:iED423DB5E4E2C3A4
GO

Sequence cautioni

The sequence BAF14845.2 differs from that shown. Reason: Erroneous gene model prediction.
The sequence CAE01570.2 differs from that shown. Reason: Erroneous gene model prediction.

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei384 – 3929LDSEYPVRN → FVLCTLYPS in isoform 2.
VSP_036267
Alternative sequencei393 – 46169Missing in isoform 2.
VSP_036268Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL606448 Genomic DNA. Translation: CAE01570.2. Sequence problems.
AP008210 Genomic DNA. Translation: BAF14845.2. Sequence problems.
RefSeqiNP_001052931.2. NM_001059466.2.
UniGeneiOs.7326.

Genome annotation databases

GeneIDi4335989.
KEGGiosa:4335989.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL606448 Genomic DNA. Translation: CAE01570.2 . Sequence problems.
AP008210 Genomic DNA. Translation: BAF14845.2 . Sequence problems.
RefSeqi NP_001052931.2. NM_001059466.2.
UniGenei Os.7326.

3D structure databases

ProteinModelPortali Q7XTC7.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 4335989.
KEGGi osa:4335989.

Organism-specific databases

Gramenei Q7XTC7.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000240114.
OMAi DFQTRAH.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C40_ORYSJ
AccessioniPrimary (citable) accession number: Q7XTC7
Secondary accession number(s): Q0JCU2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: February 10, 2009
Last modified: May 14, 2014
This is version 61 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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