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Q7XTC7

- P2C40_ORYSJ

UniProt

Q7XTC7 - P2C40_ORYSJ

Protein

Probable protein phosphatase 2C 40

Gene

Os04g0449400

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 3 (10 Feb 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi98 – 981Manganese 1By similarity
    Metal bindingi98 – 981Manganese 2By similarity
    Metal bindingi99 – 991Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi273 – 2731Manganese 2By similarity
    Metal bindingi312 – 3121Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 40 (EC:3.1.3.16)
    Short name:
    OsPP2C40
    Gene namesi
    Ordered Locus Names:Os04g0449400, LOC_Os04g37660
    ORF Names:OSJNBa0064H22.20
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 4

    Organism-specific databases

    GrameneiQ7XTC7.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 461461Probable protein phosphatase 2C 40PRO_0000363287Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ7XTC7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini56 – 314259PP2C-likeAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi2 – 87Poly-Ala

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000240114.
    OMAiDFQTRAH.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q7XTC7-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MAAAAAAATV EAVGVAGGRR RRSGSVALGD LLRREASAER ASASASAGAG    50
    GRERERRPSV AAGQACRAKK GEDFALLKPA CERLPAGGAP FSAFALFDGH 100
    NGSGAAVYAK ENILSNVMCC VPADLSGDEW LAALPRALVA GFVKTDKDFQ 150
    TRAHSSGTTV TFVIIDGYVV TVASVGDSRC VLEAEGTIYH LSADHRFDAS 200
    EEEVGRVTEC GGEVGRLNVV GGAEIGPLRC WPGGLCLSRS IGDQDVGEFI 250
    IPVPYVKQIK LSSAGGRIII SSDGVWDALT VDTAFSCARG LPPEAAADQI 300
    VKEAIASKGL RDDTTCIVID IIPPEKISPT VQPAKKAGKG LFKNIFYKKA 350
    TSDSPCHADK DQCTQPDLVE EVFEDGCPSL SRRLDSEYPV RNMFKLFICA 400
    ICQVELESGQ GISIHEGLSK SGKLRPWDGP FLCHSCQEKK EAMEGKRHSR 450
    DSSSRNSGSS E 461
    Length:461
    Mass (Da):48,707
    Last modified:February 10, 2009 - v3
    Checksum:iFB7D3035F093C1BA
    GO
    Isoform 2 (identifier: Q7XTC7-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         384-392: LDSEYPVRN → FVLCTLYPS
         393-461: Missing.

    Note: Derived from EST data. No experimental confirmation available.

    Show »
    Length:392
    Mass (Da):41,019
    Checksum:iED423DB5E4E2C3A4
    GO

    Sequence cautioni

    The sequence BAF14845.2 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence CAE01570.2 differs from that shown. Reason: Erroneous gene model prediction.

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei384 – 3929LDSEYPVRN → FVLCTLYPS in isoform 2. CuratedVSP_036267
    Alternative sequencei393 – 46169Missing in isoform 2. CuratedVSP_036268Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL606448 Genomic DNA. Translation: CAE01570.2. Sequence problems.
    AP008210 Genomic DNA. Translation: BAF14845.2. Sequence problems.
    RefSeqiNP_001052931.2. NM_001059466.2.
    UniGeneiOs.7326.

    Genome annotation databases

    GeneIDi4335989.
    KEGGiosa:4335989.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL606448 Genomic DNA. Translation: CAE01570.2 . Sequence problems.
    AP008210 Genomic DNA. Translation: BAF14845.2 . Sequence problems.
    RefSeqi NP_001052931.2. NM_001059466.2.
    UniGenei Os.7326.

    3D structure databases

    ProteinModelPortali Q7XTC7.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 4335989.
    KEGGi osa:4335989.

    Organism-specific databases

    Gramenei Q7XTC7.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000240114.
    OMAi DFQTRAH.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    3. "The rice annotation project database (RAP-DB): 2008 update."
      The rice annotation project (RAP)
      Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: cv. Nipponbare.
    4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C40_ORYSJ
    AccessioniPrimary (citable) accession number: Q7XTC7
    Secondary accession number(s): Q0JCU2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 10, 2009
    Last sequence update: February 10, 2009
    Last modified: October 1, 2014
    This is version 62 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3