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Q7XR06

- P2C45_ORYSJ

UniProt

Q7XR06 - P2C45_ORYSJ

Protein

Probable protein phosphatase 2C 45

Gene

Os04g0659500

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 2 (01 Mar 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi63 – 631Manganese 1By similarity
    Metal bindingi63 – 631Manganese 2By similarity
    Metal bindingi64 – 641Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi224 – 2241Manganese 2By similarity
    Metal bindingi263 – 2631Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: InterPro

    GO - Biological processi

    1. protein dephosphorylation Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 45 (EC:3.1.3.16)
    Short name:
    OsPP2C45
    Gene namesi
    Ordered Locus Names:Os04g0659500, LOC_Os04g56450
    ORF Names:OsJ_015762, OSJNBa0011F23.20, OSJNBa0015K02.7
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 4

    Organism-specific databases

    GrameneiQ7XR06.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 282282Probable protein phosphatase 2C 45PRO_0000363292Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ7XR06.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini26 – 265240PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000233896.
    KOiK17506.
    OMAiEEVIDHS.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.
    PROSITEiPS01032. PP2C. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q7XR06-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MGYLSSVIPT DGSPVSGGGL SQNGKFSYGY ASSPGKRASM EDFYETRIDS    50
    VDGQIIGLFG VFDGHGGAKV AEYVKQNLFS HLLRHPKFIS DTKVAIDDAY 100
    KSTDSEFLES DSSQNQCGST ASTAVLVGDR LFVANVGDSR AIICRGGNAI 150
    AVSKDHKPDQ TDERQRIEDA GGFVMWAGTW RVGGVLAVSR AFGDKLLKQY 200
    VVVDPEIREE VIDHSLEFLI LASDGLWDVV TNEEAVDMTR SIHDPEEAAK 250
    KLLQEAYKRE SSDNITCVVV RFLHGQGSSG YA 282
    Length:282
    Mass (Da):30,584
    Last modified:March 1, 2004 - v2
    Checksum:iB8FF3CF119534AB7
    GO
    Isoform 2 (identifier: Q7XR06-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         25-64: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:242
    Mass (Da):26,190
    Checksum:i8CC4D5FE1B05EA83
    GO

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei25 – 6440Missing in isoform 2. 1 PublicationVSP_036269Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL606608 Genomic DNA. Translation: CAE02890.2.
    AL662953 Genomic DNA. Translation: CAE54579.1.
    AP008210 Genomic DNA. Translation: BAF16051.1.
    CM000141 Genomic DNA. Translation: EAZ32279.1.
    AK059302 mRNA. Translation: BAG86954.1.
    AK072534 mRNA. Translation: BAG93020.1.
    RefSeqiNP_001054137.1. NM_001060672.1. [Q7XR06-2]
    UniGeneiOs.172.

    Genome annotation databases

    EnsemblPlantsiOS04T0659500-02; OS04T0659500-02; OS04G0659500. [Q7XR06-1]
    GeneIDi4337276.
    KEGGiosa:4337276.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL606608 Genomic DNA. Translation: CAE02890.2 .
    AL662953 Genomic DNA. Translation: CAE54579.1 .
    AP008210 Genomic DNA. Translation: BAF16051.1 .
    CM000141 Genomic DNA. Translation: EAZ32279.1 .
    AK059302 mRNA. Translation: BAG86954.1 .
    AK072534 mRNA. Translation: BAG93020.1 .
    RefSeqi NP_001054137.1. NM_001060672.1. [Q7XR06-2 ]
    UniGenei Os.172.

    3D structure databases

    ProteinModelPortali Q7XR06.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS04T0659500-02 ; OS04T0659500-02 ; OS04G0659500 . [Q7XR06-1 ]
    GeneIDi 4337276.
    KEGGi osa:4337276.

    Organism-specific databases

    Gramenei Q7XR06.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000233896.
    KOi K17506.
    OMAi EEVIDHS.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    PROSITEi PS01032. PP2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    3. "The rice annotation project database (RAP-DB): 2008 update."
      The rice annotation project (RAP)
      Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: cv. Nipponbare.
    4. "The genomes of Oryza sativa: a history of duplications."
      Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
      , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
      PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    5. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
      The rice full-length cDNA consortium
      Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
      Strain: cv. Nipponbare.
    6. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C45_ORYSJ
    AccessioniPrimary (citable) accession number: Q7XR06
    Secondary accession number(s): Q0J9D6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 10, 2009
    Last sequence update: March 1, 2004
    Last modified: October 1, 2014
    This is version 71 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3