Q7XQU7 (P2C41_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable protein phosphatase 2C 41
Short name=OsPP2C41
EC=3.1.3.16

Gene names

Ordered Locus Names:	Os04g0452000, Os04g0451900, LOC_Os04g37904
ORF Names:	OsJ_014406, OSJNBa0086B14.22/OSJNBa0086B14.21

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	284 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity.
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.
Sequence caution	The sequence BAF14862.2 differs from that shown. Reason: Erroneous gene model prediction. The sequence BAH01419.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence CAE02979.1 differs from that shown. Reason: Erroneous gene model prediction. Was originally thought to correspond to two different genes Os04g0451900 and Os04g0452000. The sequence CAE02980.1 differs from that shown. Reason: Erroneous gene model prediction. Was originally thought to correspond to two different genes Os04g0451900 and Os04g0452000.

Ontologies

Keywords
Ligand	Magnesium Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein dephosphorylation Inferred from electronic annotation. Source: EnsemblPlants/Gramene red light signaling pathway Inferred from electronic annotation. Source: EnsemblPlants/Gramene
Cellular_component	nucleus Inferred from electronic annotation. Source: EnsemblPlants/Gramene plasma membrane Inferred from electronic annotation. Source: EnsemblPlants/Gramene
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoprotein phosphatase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 284	284	Probable protein phosphatase 2C 41		PRO_0000363288
Regions
	Domain	34 – 275	242	PP2C-like
Sites
	Metal binding	72	1	Manganese 1 By similarity
	Metal binding	72	1	Manganese 2 By similarity
	Metal binding	73	1	Manganese 1; via carbonyl oxygen By similarity
	Metal binding	234	1	Manganese 2 By similarity
	Metal binding	273	1	Manganese 2 By similarity
Experimental info
	Sequence conflict	65	1	L → F in BAH01419. Ref.5

Sequences

	Sequence		Length	Mass (Da)
	Q7XQU7 [UniParc]. Last modified February 10, 2009. Version 2. Checksum: 15622965F0A8CD0B	FASTA	284	31,010
	10 20 30 40 50 60 MSRFCCFGAG CSEFSGHAST SSGKGKGIQG QVKVSYGFYL VRGMTNHPME DYHVAELAEE 70 80 90 100 110 120 KGNELGLFAI FDGHLGDTVP AYLQKNLFAN ILNEEEFLTQ PDRAIIKAYE KTDQAILSHT 130 140 150 160 170 180 PDLGQGGSTA VTAILLNGRK LWVANVGDSR AVLLKGGRPI QMSTDHDPNV ERSAIENRGG 190 200 210 220 230 240 FVSNMPGDVP RVCGQLAVSR AFGDRNLKSL LKSEPDIKVE DIDYTAELLV LASDGLWKVM 250 260 270 280 NNQEVVDVAK RFKDPQAAAK QLTAEALKRD SKDDISCVVV RFRM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of rice chromosome 4." Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y., Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q., Zhang L. , Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T., Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R., Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G., Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C., Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J., Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J., Li J., Hong G., Xue Y., Han B. Nature 420:316-320(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[4]	"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[5]	"Oryza sativa full length cDNA." The rice full-length cDNA consortium Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
[6]	"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis." Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y. BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL606615 Genomic DNA. Translation: CAE02979.1. Sequence problems. AL606615 Genomic DNA. Translation: CAE02980.1. Sequence problems. AP008210 Genomic DNA. Translation: BAF14862.2. Sequence problems. CM000141 Genomic DNA. Translation: EEE61099.1. AK243041 mRNA. Translation: BAH01419.1. Different initiation.
RefSeq	NP_001052948.2. NM_001059483.2.
UniGene	Os.12049.
3D structure databases
ProteinModelPortal	Q7XQU7.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os04g37904.1; LOC_Os04g37904.1; LOC_Os04g37904.
GeneID	4336006.
KEGG	osa:4336006.
Organism-specific databases
Gramene	Q7XQU7.
Phylogenomic databases
eggNOG	COG0631.
HOGENOM	HOG000233896.
OMA	GDTVPAY.
Gene expression databases
ArrayExpress	Q7XQU7.
Family and domain databases
Gene3D	3.60.40.10. 1 hit.
InterPro	IPR001932. PP2C-like. IPR015655. Protein_Pase_2C. [Graphical view]
PANTHER	PTHR13832. PTHR13832. 1 hit.
Pfam	PF00481. PP2C. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
PROSITE	PS01032. PP2C. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P2C41_ORYSJ

Accession

Primary (citable) accession number: Q7XQU7
Secondary accession number(s): B7F9X1, B9FFG5, Q7XQU8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	April 3, 2013
This is version 64 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program