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Protein

Probable protein phosphatase 2C 72

Gene

Os10g0544900

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi88Manganese 1By similarity1
Metal bindingi88Manganese 2By similarity1
Metal bindingi89Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi289Manganese 2By similarity1
Metal bindingi348Manganese 2By similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 72 (EC:3.1.3.16)
Short name:
OsPP2C72
Gene namesi
Ordered Locus Names:Os10g0544900, LOC_Os10g39780
ORF Names:OsJ_026955, OsJ_28079Imported, OSJNBa0001O14.1
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 10

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei147 – 167HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003633191 – 393Probable protein phosphatase 2C 72Add BLAST393

Proteomic databases

PaxDbiQ7XCJ7.

Expressioni

Gene expression databases

GenevisibleiQ7XCJ7. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os10g39780.1.

Structurei

3D structure databases

ProteinModelPortaliQ7XCJ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 357PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST309

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0700. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000238703.
InParanoidiQ7XCJ7.
OMAiDSNAMTT.
OrthoDBiEOG09360D2T.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 2 hits.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q7XCJ7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MLSAAMEYLR SCWGPASSPA GRPRKGSDAA GRQDGLLWYK DAGQLVAGEF
60 70 80 90 100
SMAVVQANNL LEDHSQVESG PLSTTDPNLQ GTLVGVYDGH GGPETARYIN
110 120 130 140 150
DHLFNHLRGF ASEHKCMSAD VIRKAFRATE EGFFSVVSSQ WSMRPQLAAV
160 170 180 190 200
GSCCLVGVIC AGNLYIANLG DSRAVLGRLV KGTGEVLAMQ LSAEHNASFE
210 220 230 240 250
EVRRELQAAH PDDPHIVVLK HNVWRVKGII QITRSIGDVY LKKPEFNREP
260 270 280 290 300
LHSKFRLQET FRRPLLSSEP AIVVHQLQTT DQFIIFASDG LWEHISNQEA
310 320 330 340 350
VDLVQHNPRN GIARRLVKAA MQQAAKKREM RYSDLKKIDR GVRRHFHDDI
360 370 380 390
TVVVVFFDSN AITTANWSRP SVSLRGGGVT LPANSLAPFS VPT
Length:393
Mass (Da):43,370
Last modified:October 1, 2003 - v1
Checksum:iB913270F7B7C4799
GO
Isoform 2 (identifier: Q7XCJ7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     311-334: GIARRLVKAAMQQAAKKREMRYSD → VCVLILCKLIISMAKCLFILLLVQ
     335-393: Missing.

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:334
Mass (Da):36,879
Checksum:i55429440733F3F41
GO

Sequence cautioni

The sequence AAK20060 differs from that shown. Reason: Erroneous initiation.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_036281311 – 334GIARR…MRYSD → VCVLILCKLIISMAKCLFIL LLVQ in isoform 2. CuratedAdd BLAST24
Alternative sequenceiVSP_036282335 – 393Missing in isoform 2. CuratedAdd BLAST59

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025783 Genomic DNA. Translation: AAK20060.1. Different initiation.
DP000086 Genomic DNA. Translation: AAP54876.1.
AP008216 Genomic DNA. Translation: BAF27117.1.
AP014966 Genomic DNA. Translation: BAT11893.1.
CM000145 Genomic DNA. Translation: EEE69065.1.
AK119635 mRNA. Translation: BAG99722.1.
RefSeqiXP_015614210.1. XM_015758724.1.
UniGeneiOs.3095.

Genome annotation databases

EnsemblPlantsiOS10T0544900-01; OS10T0544900-01; OS10G0544900. [Q7XCJ7-1]
GeneIDi4349275.
GrameneiOS10T0544900-01; OS10T0544900-01; OS10G0544900.
KEGGiosa:4349275.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025783 Genomic DNA. Translation: AAK20060.1. Different initiation.
DP000086 Genomic DNA. Translation: AAP54876.1.
AP008216 Genomic DNA. Translation: BAF27117.1.
AP014966 Genomic DNA. Translation: BAT11893.1.
CM000145 Genomic DNA. Translation: EEE69065.1.
AK119635 mRNA. Translation: BAG99722.1.
RefSeqiXP_015614210.1. XM_015758724.1.
UniGeneiOs.3095.

3D structure databases

ProteinModelPortaliQ7XCJ7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os10g39780.1.

Proteomic databases

PaxDbiQ7XCJ7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS10T0544900-01; OS10T0544900-01; OS10G0544900. [Q7XCJ7-1]
GeneIDi4349275.
GrameneiOS10T0544900-01; OS10T0544900-01; OS10G0544900.
KEGGiosa:4349275.

Phylogenomic databases

eggNOGiKOG0700. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000238703.
InParanoidiQ7XCJ7.
OMAiDSNAMTT.
OrthoDBiEOG09360D2T.

Gene expression databases

GenevisibleiQ7XCJ7. OS.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 2 hits.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiP2C72_ORYSJ
AccessioniPrimary (citable) accession number: Q7XCJ7
Secondary accession number(s): B9G1Z8, Q9AV42
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: October 1, 2003
Last modified: November 30, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.