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Q7XAD0 (HSY1_SOLLC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Hydroxyproline-rich systemin
Alternative name(s):
Defense-signaling glycopeptide hormone

Cleaved into the following 3 chains:

  1. HypSys I
    Alternative name(s):
    TomHypSys I
  2. HypSys II
    Alternative name(s):
    TomHypSys II
  3. HypSys III
    Alternative name(s):
    TomHypSys III
OrganismSolanum lycopersicum (Tomato) (Lycopersicon esculentum) [Reference proteome]
Taxonomic identifier4081 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanumLycopersicon

Protein attributes

Sequence length146 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Activates a lipid-based signal transduction pathway in which linolenic acid is converted to jasmonic acid, a potent activator of defense gene transcription. Induces synthesis of proteinase inhibitors I and II in leaves when supplied through cut stems. Ref.1

Subcellular location

Secreted.

Tissue specificity

Leaves. Ref.1

Induction

By wounding and methyl jasmonate in leaves. Ref.1

Post-translational modification

O-glycosylated; contains pentose side chains. Ref.1

Mass spectrometry

Molecular mass is 4191 Da from positions 49 - 66. Determined by MALDI. Ref.1

Molecular mass is 3531 Da from positions 49 - 66. Determined by MALDI. Ref.1

Molecular mass is 2954 Da from positions 71 - 85. Determined by MALDI. Ref.1

Molecular mass is 4513 Da from positions 111 - 130. Determined by MALDI. Ref.1

Ontologies

Keywords
   Biological processPlant defense
   Cellular componentSecreted
   DomainSignal
   Molecular functionHormone
   PTMGlycoprotein
Hydroxylation
   Technical termComplete proteome
Direct protein sequencing
Reference proteome
Gene Ontology (GO)
   Biological_processdefense response

Inferred from direct assay Ref.1. Source: UniProtKB

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

intracellular

Non-traceable author statement Ref.1. Source: UniProtKB

   Molecular_functionbinding

Inferred from direct assay Ref.1. Source: UniProtKB

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2424 Potential
Propeptide25 – 4824 Ref.1
PRO_0000021449
Peptide49 – 6618HypSys I Ref.1
PRO_0000021450
Propeptide67 – 704 Ref.1
PRO_0000021451
Peptide71 – 8515HypSys III Ref.1
PRO_0000021452
Propeptide86 – 11025 Ref.1
PRO_0000021453
Peptide111 – 13020HypSys II Ref.1
PRO_0000021454
Propeptide131 – 14616 Ref.1
PRO_0000021455

Amino acid modifications

Modified residue5114-hydroxyproline Ref.1
Modified residue5514-hydroxyproline Ref.1
Modified residue5614-hydroxyproline Ref.1
Modified residue5714-hydroxyproline Ref.1
Modified residue5814-hydroxyproline Ref.1
Modified residue6314-hydroxyproline Ref.1
Modified residue7914-hydroxyproline Ref.1
Modified residue8014-hydroxyproline Ref.1
Modified residue8214-hydroxyproline Ref.1
Modified residue11914-hydroxyproline Ref.1
Modified residue12014-hydroxyproline Ref.1
Modified residue12114-hydroxyproline Ref.1
Modified residue12214-hydroxyproline Ref.1
Glycosylation511O-linked (Ara...) Potential
Glycosylation551O-linked (Ara...) Potential
Glycosylation561O-linked (Ara...) Potential
Glycosylation571O-linked (Ara...) Potential
Glycosylation581O-linked (Ara...) Potential
Glycosylation631O-linked (Ara...) Potential
Glycosylation791O-linked (Ara...) Potential
Glycosylation801O-linked (Ara...) Potential
Glycosylation821O-linked (Ara...) Potential
Glycosylation1191O-linked (Ara...) Potential
Glycosylation1201O-linked (Ara...) Potential
Glycosylation1211O-linked (Ara...) Potential
Glycosylation1221O-linked (Ara...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q7XAD0 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 115E92B146A31973

FASTA14616,012
        10         20         30         40         50         60 
MISFFRAFFL IIIISFLIFV GAQARTLLGN YHDDEMLIEL KLESGNYGRT PYKTPPPPTS 

        70         80         90        100        110        120 
SSPTHQEIVN GRHDSVLPPP SPKTDPIIGQ LTTITTTPHH DDTVAAPPVG GRHDYVASPP 

       130        140 
PPKPQDEQRQ IIITSSSSTL PLQASY 

« Hide

References

[1]"Systemic signaling in tomato plants for defense against herbivores: isolation and characterization of three novel defense-signaling glycopeptide hormones coded in a single precursor gene."
Pearce G., Ryan C.A.
J. Biol. Chem. 278:30044-30050(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 49-66; 71-85 AND 111-125, FUNCTION, TISSUE SPECIFICITY, MASS SPECTROMETRY, GLYCOSYLATION.
Strain: cv. Castlemart.
[2]"Systemins: a functionally defined family of peptide signals that regulate defensive genes in Solanaceae species."
Ryan C.A., Pearce G.
Proc. Natl. Acad. Sci. U.S.A. 100:14577-14580(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: REVIEW ON FUNCTION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY292201 mRNA. Translation: AAQ19087.1.
RefSeqNP_001234375.1. NM_001247446.1.
UniGeneLes.2121.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsSolyc06g068520.2.1; Solyc06g068520.2.1; Solyc06g068520.2.
GeneID543883.
KEGGsly:543883.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameHSY1_SOLLC
AccessionPrimary (citable) accession number: Q7XAD0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: October 1, 2003
Last modified: February 19, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program