Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Elongator complex protein 3

Gene

ELP3

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Histone acetyltransferase. Part of the large multiprotein complex Elongator that is involved in the regulation of transcription initiation and elongation. May also have a methyltransferase activity (By similarity).By similarity

Catalytic activityi

Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N6-acetyl-L-lysine.

Cofactori

[4Fe-4S] clusterBy similarityNote: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi125Iron-sulfur (4Fe-4S-S-AdoMet)By similarity1
Metal bindingi135Iron-sulfur (4Fe-4S-S-AdoMet)By similarity1
Metal bindingi138Iron-sulfur (4Fe-4S-S-AdoMet)By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase
Biological processTranscription, Transcription regulation
LigandIron, Iron-sulfur, Metal-binding, S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Elongator complex protein 3 (EC:2.3.1.48)
Alternative name(s):
Elongator component 3
Gene namesi
Name:ELP3
Ordered Locus Names:Os04g0484900, LOC_Os04g40840
ORF Names:OJ000223_09.4, OSJNBa0081L15.14
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002321291 – 573Elongator complex protein 3Add BLAST573

Proteomic databases

PaxDbiQ7X7L3
PRIDEiQ7X7L3

Expressioni

Gene expression databases

GenevisibleiQ7X7L3 OS

Interactioni

Subunit structurei

Part of the Elongator core subcomplex.

Protein-protein interaction databases

STRINGi39947.LOC_Os04g40840.1

Structurei

3D structure databases

ProteinModelPortaliQ7X7L3
SMRiQ7X7L3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini422 – 573N-acetyltransferasePROSITE-ProRule annotationAdd BLAST152

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi9 – 14Poly-Gly6

Sequence similaritiesi

Belongs to the ELP3 family.Curated

Phylogenomic databases

eggNOGiKOG2535 Eukaryota
COG1243 LUCA
HOGENOMiHOG000227514
InParanoidiQ7X7L3
KOiK07739
OMAiSYTGKEP
OrthoDBiEOG093605YI

Family and domain databases

Gene3Di3.80.30.20, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR034687 ELP3-like
IPR006638 Elp3/MiaB/NifB
IPR000182 GNAT_dom
IPR032432 Radical_SAM_C
IPR007197 rSAM
IPR023404 rSAM_horseshoe
PANTHERiPTHR11135:SF0 PTHR11135:SF0, 1 hit
PfamiView protein in Pfam
PF00583 Acetyltransf_1, 1 hit
PF04055 Radical_SAM, 1 hit
PF16199 Radical_SAM_C, 1 hit
PIRSFiPIRSF005669 Hist_AcTrfase_ELP3, 1 hit
SFLDiSFLDF00344 ELP3-like, 1 hit
SFLDS00029 Radical_SAM, 1 hit
SMARTiView protein in SMART
SM00729 Elp3, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
TIGRFAMsiTIGR01211 ELP3, 1 hit
PROSITEiView protein in PROSITE
PS51186 GNAT, 1 hit

Sequencei

Sequence statusi: Complete.

Q7X7L3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATAVAAAGG GGGGEQPRRR KPAPGRGGVV LPAGLSEEEA RVRAIAEIVS
60 70 80 90 100
AMGELSRRGE DVDLNALKSA ACRRYGLARA PKLVEMIAAV PEADRAALLP
110 120 130 140 150
RLRAKPVRTA SGIAVVAVMS KPHRCPHIAT TGNICVYCPG GPDSDFEYST
160 170 180 190 200
QSYTGYEPTS MRAIRARYNP YVQARSRIDQ LKRLGHSVDK VEFILMGGTF
210 220 230 240 250
MSLPADYRDY FIRNLHDALS GHTSANVEEA VCYSEHGAVK CIGMTIETRP
260 270 280 290 300
DYCLGPHLRQ MLSYGCTRLE IGVQSTYEDV ARDTNRGHTV AAVADCFCLA
310 320 330 340 350
KDAGFKVVAH MMPDLPNVGV ERDLESFREF FENPAFRADG LKIYPTLVIR
360 370 380 390 400
GTGLYELWKT GRYRNYPPEL LVDIVARILS MVPPWTRVYR VQRDIPMPLV
410 420 430 440 450
TSGVEKGNLR ELALARMEDL GLKCRDVRTR EAGIQDIHHK IRPDEVELVR
460 470 480 490 500
RDYAANEGWE TFLSYEDTQQ DILIGLLRLR KCGRNVTCPE LVGRCSIVRE
510 520 530 540 550
LHVYGTAVPV HGRDADKLQH QGYGTLLMEE AERIARKEHR SKKIAVISGV
560 570
GTRHYYRKLG YELEGPYMVK CLV
Length:573
Mass (Da):63,775
Last modified:July 5, 2004 - v2
Checksum:i9CCDB95C057F2B54
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL606623 Genomic DNA Translation: CAE03152.2
AL606998 Genomic DNA Translation: CAE02005.2
AP008210 Genomic DNA Translation: BAF15042.1
AP014960 Genomic DNA Translation: BAS89780.1
AK122179 mRNA Translation: BAH00832.1
RefSeqiXP_015635801.1, XM_015780315.1
UniGeneiOs.17516

Genome annotation databases

EnsemblPlantsiOs04t0484900-01; Os04t0484900-01; Os04g0484900
GeneIDi4336205
GrameneiOs04t0484900-01; Os04t0484900-01; Os04g0484900
KEGGiosa:4336205

Similar proteinsi

Entry informationi

Entry nameiELP3_ORYSJ
AccessioniPrimary (citable) accession number: Q7X7L3
Secondary accession number(s): Q0JC95
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 105 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health