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Q7X7L3 (ELP3_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Elongator complex protein 3
EC=2.3.1.48
Alternative name(s):
Elongator component 3
Gene names
Name:ELP3
Ordered Locus Names:Os04g0484900, LOC_Os04g40840
ORF Names:OJ000223_09.4, OSJNBa0081L15.14
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza ›

Protein attributes

Sequence length573 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Histone acetyltransferase. Part of the large multiprotein complex Elongator that is involved in the regulation of transcription initiation and elongation. May also have a methyltransferase activity By similarity.

Catalytic activity

Acetyl-CoA + [histone] = CoA + acetyl-[histone].

Cofactor

Binds 1 4Fe-4S cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine By similarity.

Subunit structure

Part of the Elongator core subcomplex.

Subcellular location

Nucleus Probable.

Sequence similarities

Belongs to the ELP3 family.

Contains 1 N-acetyltransferase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 573573Elongator complex protein 3
PRO_0000232129

Regions

Domain422 – 573152N-acetyltransferase
Compositional bias9 – 146Poly-Gly

Sites

Metal binding1251Iron-sulfur (4Fe-4S-S-AdoMet) By similarity
Metal binding1351Iron-sulfur (4Fe-4S-S-AdoMet) By similarity
Metal binding1381Iron-sulfur (4Fe-4S-S-AdoMet) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7X7L3 [UniParc].

Last modified July 5, 2004. Version 2.
Checksum: 9CCDB95C057F2B54

FASTA57363,775
        10         20         30         40         50         60 
MATAVAAAGG GGGGEQPRRR KPAPGRGGVV LPAGLSEEEA RVRAIAEIVS AMGELSRRGE 

        70         80         90        100        110        120 
DVDLNALKSA ACRRYGLARA PKLVEMIAAV PEADRAALLP RLRAKPVRTA SGIAVVAVMS 

       130        140        150        160        170        180 
KPHRCPHIAT TGNICVYCPG GPDSDFEYST QSYTGYEPTS MRAIRARYNP YVQARSRIDQ 

       190        200        210        220        230        240 
LKRLGHSVDK VEFILMGGTF MSLPADYRDY FIRNLHDALS GHTSANVEEA VCYSEHGAVK 

       250        260        270        280        290        300 
CIGMTIETRP DYCLGPHLRQ MLSYGCTRLE IGVQSTYEDV ARDTNRGHTV AAVADCFCLA 

       310        320        330        340        350        360 
KDAGFKVVAH MMPDLPNVGV ERDLESFREF FENPAFRADG LKIYPTLVIR GTGLYELWKT 

       370        380        390        400        410        420 
GRYRNYPPEL LVDIVARILS MVPPWTRVYR VQRDIPMPLV TSGVEKGNLR ELALARMEDL 

       430        440        450        460        470        480 
GLKCRDVRTR EAGIQDIHHK IRPDEVELVR RDYAANEGWE TFLSYEDTQQ DILIGLLRLR 

       490        500        510        520        530        540 
KCGRNVTCPE LVGRCSIVRE LHVYGTAVPV HGRDADKLQH QGYGTLLMEE AERIARKEHR 

       550        560        570 
SKKIAVISGV GTRHYYRKLG YELEGPYMVK CLV

« Hide

References

[1]"Sequence and analysis of rice chromosome 4."
Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y., Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q., Zhang L. expand/collapse author list , Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T., Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R., Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G., Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C., Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J., Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J., Li J., Hong G., Xue Y., Han B.
Nature 420:316-320(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL606998 Genomic DNA. Translation: CAE02005.2.
AL606623 Genomic DNA. Translation: CAE03152.2.
AK122179 mRNA. No translation available.
RefSeqNP_001053128.1. NM_001059663.1.
UniGeneOs.17516.

3D structure databases

ProteinModelPortalQ7X7L3.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsLOC_Os04g40840.1; LOC_Os04g40840.1; LOC_Os04g40840.
GeneID4336205.
KEGGosa:4336205.

Organism-specific databases

GrameneQ7X7L3.

Phylogenomic databases

eggNOGCOG1243.
HOGENOMHOG000227514.
KOK07739.
OMAGIQEVHH.
ProtClustDBCLSN2689971.

Gene expression databases

ArrayExpressQ7X7L3.

Family and domain databases

Gene3D3.40.630.30. 1 hit.
3.80.30.20. 1 hit.
InterProIPR016181. Acyl_CoA_acyltransferase.
IPR006638. Elp3/MiaB/NifB.
IPR000182. GNAT_dom.
IPR005910. Hist_AcTrfase_ELP3.
IPR007197. rSAM.
IPR023404. rSAM_horseshoe.
[Graphical view]
PfamPF00583. Acetyltransf_1. 1 hit.
PF04055. Radical_SAM. 1 hit.
[Graphical view]
PIRSFPIRSF005669. Hist_AcTrfase_ELP3. 1 hit.
SMARTSM00729. Elp3. 1 hit.
[Graphical view]
SUPFAMSSF55729. Acyl_CoA_acyltransferase. 1 hit.
TIGRFAMsTIGR01211. ELP3. 1 hit.
PROSITEPS51186. GNAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameELP3_ORYSJ
AccessionPrimary (citable) accession number: Q7X7L3
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: July 5, 2004
Last modified: April 3, 2013
This is version 68 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

SIMILARITY comments

Index of protein domains and families

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