Q7WZE5 (KGUA_SHEVD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Guanylate kinase
EC=2.7.4.8

Alternative name(s):
GMP kinase

Gene names

Name:	gmk
Ordered Locus Names:	SVI_4076

Organism

Shewanella violacea (strain JCM 10179 / CIP 106290 / LMG 19151 / DSS12) [Complete proteome] [HAMAP]

Taxonomic identifier

637905 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella › Shewanella violacea

Protein attributes

Sequence length	207 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Essential for recycling GMP and indirectly, cGMP By similarity. HAMAP-Rule MF_00328
Catalytic activity	ATP + GMP = ADP + GDP. HAMAP-Rule MF_00328
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00328.
Sequence similarities	Belongs to the guanylate kinase family. Contains 1 guanylate kinase-like domain.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	purine nucleotide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW guanylate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 207	207	Guanylate kinase HAMAP-Rule MF_00328		PRO_0000170601
Regions
	Domain	5 – 184	180	Guanylate kinase-like
	Nucleotide binding	12 – 19	8	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7WZE5 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 009B66B45E24D1A1	FASTA	207	23,025
	10 20 30 40 50 60 MTARGNLFIV SAPSGAGKSS LISALLQDKP ADKQVSVSHT TRQPRPGEVN GQHYHFVTKE 70 80 90 100 110 120 EFKALITENA FFEWAEVFGN YYGTSRKVIE QTLTDGIDVF LDIDWQGAQQ VKKVMPEAIG 130 140 150 160 170 180 IFILPPSRTE LEKRLTGRGQ DSKEVIASRM AQAASEISHY NEYDFIIIND DFDTALADLV 190 200 AIIRSQRLTD TGQIHAHNDM IQGLLAD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning and purification of the rpoZ gene encoding RNA polymerase omega subunit from deep-sea piezophilic bacterium, Shewanella violacea strain DSS12." Kawano H., Suzaki Y., Fukuchi J., Nakasone K., Abe F., Kato C., Yoshida Y., Usami R., Horikoshi K. Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete genome sequence and comparative analysis of Shewanella violacea, a psychrophilic and piezophilic bacterium from deep sea floor sediments." Aono E., Baba T., Ara T., Nishi T., Nakamichi T., Inamoto E., Toyonaga H., Hasegawa M., Takai Y., Okumura Y., Baba M., Tomita M., Kato C., Oshima T., Nakasone K., Mori H. Mol. Biosyst. 6:1216-1226(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JCM 10179 / CIP 106290 / LMG 19151 / DSS12.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB114448 Genomic DNA. Translation: BAC79233.1. AP011177 Genomic DNA. Translation: BAJ04047.1.
RefSeq	YP_003558825.1. NC_014012.1.
3D structure databases
ProteinModelPortal	Q7WZE5.
SMR	Q7WZE5. Positions 3-207.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAJ04047; BAJ04047; SVI_4076.
GeneID	8967802.
KEGG	svo:SVI_4076.
PATRIC	35464344. VBISheVio92117_3913.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000037638.
KO	K00942.
OMA	FVIINEL.
ProtClustDB	PRK00300.
Enzyme and pathway databases
BioCyc	SVIO637905:GCRO-4229-MONOMER.
Family and domain databases
HAMAP	MF_00328. Guanylate_kinase.
InterPro	IPR008144. Guanylate_kin. IPR008145. Guanylate_kin/L-typ_Ca_channel. IPR020590. Guanylate_kinase_CS. IPR017665. Guanylate_kinase_sub. IPR027417. P-loop_NTPase. [Graphical view]
Pfam	PF00625. Guanylate_kin. 1 hit. [Graphical view]
SMART	SM00072. GuKc. 1 hit. [Graphical view]
SUPFAM	SSF52540. SSF52540. 1 hit.
TIGRFAMs	TIGR03263. guanyl_kin. 1 hit.
PROSITE	PS00856. GUANYLATE_KINASE_1. 1 hit. PS50052. GUANYLATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KGUA_SHEVD

Accession

Primary (citable) accession number: Q7WZE5
Secondary accession number(s): D4ZDY6

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2004
Last sequence update:	October 1, 2003
Last modified:	May 29, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program