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Protein
Submitted name:

Cellulosomal scaffoldin adaptor protein B

Gene

scaB

Organism
Acetivibrio cellulolyticus
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi873 – 8731Calcium 1Combined sources
Metal bindingi875 – 8751Calcium 1Combined sources
Metal bindingi877 – 8771Calcium 1Combined sources
Metal bindingi879 – 8791Calcium 1; via carbonyl oxygenCombined sources
Metal bindingi884 – 8841Calcium 1Combined sources
Metal bindingi909 – 9091Calcium 2Combined sources
Metal bindingi911 – 9111Calcium 2Combined sources
Metal bindingi913 – 9131Calcium 2Combined sources
Metal bindingi915 – 9151Calcium 2; via carbonyl oxygenCombined sources
Metal bindingi920 – 9201Calcium 2Combined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

CalciumCombined sources, Metal-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Cellulosomal scaffoldin adaptor protein BImported
Gene namesi
Name:scaBImported
OrganismiAcetivibrio cellulolyticusImported
Taxonomic identifieri35830 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeAcetivibrio

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727Sequence analysisAdd
BLAST
Chaini28 – 942915Sequence analysisPRO_5004293706Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi509191.AcelC_020100011443.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1QZNX-ray1.90A27-199[»]
1ZV9X-ray1.28A28-199[»]
3BWZX-ray1.20A28-199[»]
3F2LX-ray1.85A28-199[»]
3FNKX-ray1.99A/B/C190-368[»]
3GHPX-ray2.49A/B190-408[»]
3L8QX-ray1.57A/B/C/D28-368[»]
4U3SX-ray1.64A407-573[»]
4UYPX-ray1.49B/D868-942[»]
4UYQX-ray1.81B868-942[»]
4WI0X-ray1.93A407-573[»]
ProteinModelPortaliQ7WYN3.
SMRiQ7WYN3. Positions 28-199.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ7WYN3.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini867 – 93771DockerinInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4106IYM. Bacteria.
ENOG410Y95A. LUCA.

Family and domain databases

Gene3Di1.10.1330.10. 1 hit.
2.60.40.680. 4 hits.
InterProiIPR008965. Carb-bd_dom.
IPR002102. Cohesin_dom.
IPR016134. Dockerin_dom.
[Graphical view]
PfamiPF00963. Cohesin. 4 hits.
[Graphical view]
SUPFAMiSSF49384. SSF49384. 4 hits.
SSF63446. SSF63446. 1 hit.
PROSITEiPS51766. DOCKERIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7WYN3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVNRILSFL LTLMLVIYSL CGNLINAAPT SSIEIVLDKT TASVGEIVTA
60 70 80 90 100
SINIKNITNF SGCQLNMKYD PAVLQPVTSS GVAYTKSTMP GAGTILNSDF
110 120 130 140 150
NLRQVADNDL EKGILNFSKA YVSLDDYRTA AAPEQTGTVA VVKFKVLKEE
160 170 180 190 200
TSSISFEDTT SVPNAIDGTV LFDWNGDRIQ SGYSVIQPAV INLDMIKASY
210 220 230 240 250
ITMGYDKNAA EVGEIIKATV KINKITNFSG YQVNIKYDPT VLQAVNPKTG
260 270 280 290 300
VAYTNSSLPT SGELLVSEDY GPIVQGVHKI SEGILNLSRS YTALEVYRAS
310 320 330 340 350
ESPEETGTLA VVGFKVLQKK ATTVVFEDSE TMPNGITGTT LFNWYGNRIQ
360 370 380 390 400
SGYFVIQPGE INSAPIATAT PTTKPTAFAS TMPTVTLTPT PTATTTTTIP
410 420 430 440 450
TAVPTTESYI TMNFDKNTAE VGQIIKATVK INKITNFSGY QVNIKYDPTV
460 470 480 490 500
LQAVNPKTGV AYTNSSLPTS GELLVNEDYG PIVQGVHKIS EGILNLSRSY
510 520 530 540 550
TALDVYRASE SPEETGTVAV VGFKALQKKA TTVVFEHSVT MPNGIIGTTL
560 570 580 590 600
FNWYGNRITS GYSVIQPGEI NSETITTPTP TATPTIIVTP TPTATATPTI
610 620 630 640 650
VVTPTVKPTP TSTGDSYITI DLDKTDVSVG DIIKASVRIN DISNFSGYQV
660 670 680 690 700
NIKYDTTVLQ AVNPKTGAEY KNDSLPLEGE ILANQDYSPF PTCDNIISEG
710 720 730 740 750
LLNFGKLYTA LDVYKESNLA EKSGVVAVVG FKVIKAKNTA ITFEDCDSMP
760 770 780 790 800
SGITGTMLFN WDGEIIKSGY SIMQPAAITV RSVTPTATAT PTATPTKTAT
810 820 830 840 850
PTPTQTATPT PTQTATPTAT QTATATATAT ATATPTATAT ATPTATATPT
860 870 880 890 900
ATATTTPTTT PTTTPTPKFI YGDVDGNGSV RINDAVLIRD YVLGKINEFP
910 920 930 940
YEYGMLAADV DGNGSIKIND AVLVRDYVLG KIFLFPVEEK EE
Length:942
Mass (Da):100,359
Last modified:October 1, 2003 - v1
Checksum:iCABB5A638B352CA9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY221112 Genomic DNA. Translation: AAP48995.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY221112 Genomic DNA. Translation: AAP48995.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1QZNX-ray1.90A27-199[»]
1ZV9X-ray1.28A28-199[»]
3BWZX-ray1.20A28-199[»]
3F2LX-ray1.85A28-199[»]
3FNKX-ray1.99A/B/C190-368[»]
3GHPX-ray2.49A/B190-408[»]
3L8QX-ray1.57A/B/C/D28-368[»]
4U3SX-ray1.64A407-573[»]
4UYPX-ray1.49B/D868-942[»]
4UYQX-ray1.81B868-942[»]
4WI0X-ray1.93A407-573[»]
ProteinModelPortaliQ7WYN3.
SMRiQ7WYN3. Positions 28-199.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi509191.AcelC_020100011443.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4106IYM. Bacteria.
ENOG410Y95A. LUCA.

Miscellaneous databases

EvolutionaryTraceiQ7WYN3.

Family and domain databases

Gene3Di1.10.1330.10. 1 hit.
2.60.40.680. 4 hits.
InterProiIPR008965. Carb-bd_dom.
IPR002102. Cohesin_dom.
IPR016134. Dockerin_dom.
[Graphical view]
PfamiPF00963. Cohesin. 4 hits.
[Graphical view]
SUPFAMiSSF49384. SSF49384. 4 hits.
SSF63446. SSF63446. 1 hit.
PROSITEiPS51766. DOCKERIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The cellulosome system of Acetivibrio cellulolyticus includes a novel type of adaptor protein and a cell surface anchoring protein."
    Xu Q., Gao W., Ding S.Y., Kenig R., Shoham Y., Bayer E.A., Lamed R.
    J. Bacteriol. 185:4548-4557(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Crystal structure of a type-II cohesin module from the Bacteroides cellulosolvens cellulosome reveals novel and distinctive secondary structural elements."
    Noach I., Frolow F., Jakoby H., Rosenheck S., Shimon L.W., Lamed R., Bayer E.A.
    J. Mol. Biol. 348:1-12(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 27-199.
  3. "Crystal structure analysis of the K171A mutation of N-terminal type II cohesin 1 from the cellulosomal ScaB subunit of Acetivibrio cellulolyticus."
    Frolow F., Freeman A., Wine Y., Eppel A., Shanzer M., Stempler S.
    Submitted (OCT-2008) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) OF 28-199.
  4. "Intermodular linker flexibility revealed from crystal structures of adjacent cellulosomal cohesins of Acetivibrio cellulolyticus."
    Noach I., Frolow F., Alber O., Lamed R., Shimon L.J., Bayer E.A.
    J. Mol. Biol. 391:86-97(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.20 ANGSTROMS) OF 28-199.
  5. "Modular arrangement of a cellulosomal scaffoldin subunit revealed from the crystal structure of a cohesin dyad."
    Noach I., Levy-Assaraf M., Lamed R., Shimon L.J., Frolow F., Bayer E.A.
    J. Mol. Biol. 399:294-305(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.57 ANGSTROMS) OF 28-368.
  6. "Crystal structure of Coh3ScaB-XDoc_M1ScaA complex: A N-terminal interface mutant of type II Cohesin-X-Dockerin complex from Acetivibrio cellulolyticus."
    Alves V.D., Cameron K., Najmudin S.H., Fontes C.M.G.A.
    Submitted (JUL-2014) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.64 ANGSTROMS) OF 407-573.
  7. "Crystal structure of Coh3ScaB-XDoc_M1ScaA complex: A C-terminal interface mutant of type II Cohesin-X-Dockerin complex from Acetivibrio cellulolyticus."
    Alves V.D., Cameron K., Najmudin S.H., Fontes C.M.G.A.
    Submitted (SEP-2014) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.93 ANGSTROMS) OF 407-573.
  8. "Cell-surface Attachment of Bacterial Multienzyme Complexes Involves Highly Dynamic Protein-Protein Anchors."
    Cameron K., Najmudin S., Alves V.D., Bayer E.A., Smith S.P., Bule P., Waller H., Ferreira L.M., Gilbert H.J., Fontes C.M.
    J. Biol. Chem. 290:13578-13590(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.49 ANGSTROMS) OF 868-942 IN COMPLEX WITH CALCIUM.

Entry informationi

Entry nameiQ7WYN3_9FIRM
AccessioniPrimary (citable) accession number: Q7WYN3
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: April 13, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.