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Q7WTU1 (PGK_SPICI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
OrganismSpiroplasma citri
Taxonomic identifier2133 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesEntomoplasmatalesSpiroplasmataceaeSpiroplasma

Protein attributes

Sequence length412 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 412412Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000146000

Regions

Nucleotide binding368 – 3714ATP By similarity
Region22 – 243Substrate binding By similarity
Region60 – 634Substrate binding By similarity

Sites

Binding site371Substrate By similarity
Binding site1201Substrate By similarity
Binding site1721Substrate By similarity
Binding site2231ATP By similarity
Binding site3101ATP; via carbonyl oxygen By similarity
Binding site3411ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7WTU1 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 1F2C0787686A147F

FASTA41244,388
        10         20         30         40         50         60 
MTNKKELKDV QVKGKKVLVR VDFNVPMKDG QVTDDNRIIA ALPTIKYLIA QEAKVILFSH 

        70         80         90        100        110        120 
LGKVKTADDL EKRDMAPVAK VLEQKLGQPV KFINAFEGKQ LEEAINEMHN KEVILFQNTR 

       130        140        150        160        170        180 
FADIINSNGQ ISVDSEGKAA AKRESKNDSA LGKYWASLGD VFVNDAFGTA HRAHASNVGI 

       190        200        210        220        230        240 
AENITESCLG FLVEKEVKML SQCVDNPVKP FVAIIGGAKV SDKIGVIEHL LTKADKILIG 

       250        260        270        280        290        300 
GGMAYTFFAA QGHKIGNSLL EVDKVEIAKT FLAKGQGKII LPIDALEAPE FADVPAKVTT 

       310        320        330        340        350        360 
GFDIDDGYMG LDIGPKTIEL FKKELADAKT VTWNGPMGVF EFKNYSIGTK AVCEAIAELK 

       370        380        390        400        410 
GAFTLIGGGD SAAAAIQLGY KDKFTHISTG GGASLEYMEG KPLPGIEAVQ SK 

« Hide

References

[1]"Genome sequence of Spiroplasma citri the plant pathogen and phloem restricted mollicute."
Foissac X., Carle P., Saillard C., Blanchard A.
Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: GII3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ580006 Genomic DNA. Translation: CAE30465.1.

3D structure databases

ProteinModelPortalQ7WTU1.
SMRQ7WTU1. Positions 3-412.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ7WTU1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_SPICI
AccessionPrimary (citable) accession number: Q7WTU1
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: October 1, 2003
Last modified: February 19, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways