Q7WTN6 (Q7WTN6_RHOMR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Xylanase EMBL CAA72323.2
Organism	Rhodothermus marinus (Rhodothermus obamensis) EMBL CAA72323.2
Taxonomic identifier	29549 [NCBI]
Taxonomic lineage	cellular organisms › Bacteria › Bacteroidetes/Chlorobi group › Bacteroidetes › Bacteroidetes Order II. Incertae sedis › Rhodothermaceae › Rhodothermus

Protein attributes

Sequence length	997 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Biological process	Xylan degradation EMBL CAA72323.2
Ligand	Calcium PDB 3JXS Metal-binding PDB 3JXS
Technical term	3D-structure PDB 3JXS PDB 2Y64 PDB 2Y6G PDB 2Y6H PDB 2Y6J PDB 2Y6K PDB 2Y6L
Gene Ontology (GO)
Biological_process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	219	1	Calcium 1; via carbonyl oxygen PDB 3JXS
	Metal binding	221	1	Calcium 1 PDB 3JXS
	Metal binding	232	1	Calcium 2; via carbonyl oxygen PDB 3JXS
	Metal binding	238	1	Calcium 2; via carbonyl oxygen PDB 3JXS
	Metal binding	239	1	Calcium 2 PDB 3JXS
	Metal binding	262	1	Calcium 1 PDB 3JXS
	Metal binding	265	1	Calcium 1; via carbonyl oxygen PDB 3JXS
	Metal binding	370	1	Calcium 1 PDB 3JXS

Sequences

	Sequence		Length	Mass (Da)
	Q7WTN6 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: CE6ABF99CC4AC1A9	FASTA	997	110,343
	10 20 30 40 50 60 MRTATDLRFL RNAVGNASRS AIFLFLVFSL VGQAWGQTPA NVNGSFESTP AGVVTDLAGG 70 80 90 100 110 120 VEGWVLNVGS LVTNPPVFEV VEATDAPHGS KVLAVTVNGA GNNPWDIEAT AFPVNVEPGV 130 140 150 160 170 180 TYTYTIWARA EQDGAVVSFT VGNQSYQEYG RLHEQQITTE WQPYTFEFTV SDQETVIRAP 190 200 210 220 230 240 IHFGYAANAG NTIYIDALVI MGPEPEPAGP ELVANINGGF ESTPAGVVTD LAEGVEGWDL 250 260 270 280 290 300 NVGSSVTNPP VFEVLETSDA PEGNKVLAVT VNGVGNNPWD IEATAFPVNV RPGVTYTYTI 310 320 330 340 350 360 WARAEQDGAV VSFTVGNQSF QEYGRLHEQQ ITTEWQPFTF EFTVSDQETV IRAPIHFGYA 370 380 390 400 410 420 ANVGNTIYID GLAIVDSVGA WRPVIVEAED GELGSEWAVE TEGNVTYITI TTDYNETTGD 430 440 450 460 470 480 ADHPGENRTA TYQVTFPAPG WYDLYARVYV GPETFNDDSF FYADSFGVKD PESPDDWIIA 490 500 510 520 530 540 NQLRAAGYTE PDEYVTGLGA AGSEVWKWIN LSENSFNDVP SDSFYVSPES LTVTFMIGAR 550 560 570 580 590 600 ENGLRIDKLA FGRSDLLYTV ADLDTGGPGS PEPEEPPVVL PERPLAADVD KFLGNIYSPS 610 620 630 640 650 660 QVENFEYYWN CVTPENAGKW GSVEGTRDQM NWSSLDAAYA LARDNGFCFN FHVLLWGAQQ 670 680 690 700 710 720 PAWISELSPE EQLEEIQEWF QAVAERYSFT ASPFDVVQVV NEPLHQPPDG QEGRANYIEA 730 740 750 760 770 780 LGGAGETGWD WVITAFELAR QIFPEGTRLM INDYGILSSL ETAQQYLELI QLLKERNLID 790 800 810 820 830 840 VIGVQGHAFS TRSGAPIQEV LDLLATTGLP IQVTEMDIDG NPNQSPFVTR EQSEQNQLRD 850 860 870 880 890 900 MQRIFPTVWY HPAVEGVTFW GWRPGLWRND YEAYLVYSNG AERPAMVWLR EFMEAYRESY 910 920 930 940 950 960 LSANEPEGTL PEELSVVSWP NPSRGQVRFR YALPFEAEVR LQVFDVLGRE VMTLASGRHR 970 980 990 AGVYEVAFDG RHLPSGLYLY RLEANGRVRS GRLVLMR

References

[1]	"Cloning and sequence of a thermostable multidomain xylanase from the bacterium Rhodothermus marinus." Nordberg Karlsson E., Bartonek-Roxa E., Holst O. Biochim. Biophys. Acta 1353:118-124(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Nordberg Karlsson E.M. Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	"The crystal structure of XG-34, an evolved xyloglucan-specific carbohydrate-binding module." Gullfot F., Tan T.C., von Schantz L., Karlsson E.N., Ohlin M., Brumer H., Divne C. Proteins 78:785-789(2010) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) OF 212-376 IN COMPLEX WITH CALCIUM.
[4]	"Structural basis for carbohydrate-binding specificity--a comparative assessment of two engineered carbohydrate-binding modules." von Schantz L., Hakansson M., Logan D.T., Walse B., Osterlin J., Nordberg-Karlsson E., Ohlin M. Glycobiology 22:948-961(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.08 ANGSTROMS) OF 212-376.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

Y11564 Genomic DNA. Translation: CAA72323.2.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2Y64	X-ray	1.40	A	212-376	[»]
2Y6G	X-ray	1.30	A	212-376	[»]
2Y6H	X-ray	1.08	A	212-376	[»]
2Y6J	X-ray	1.70	A	212-376	[»]
2Y6K	X-ray	1.36	A	212-376	[»]
2Y6L	X-ray	1.28	A	212-376	[»]
3JXS	X-ray	1.60	A/B/C	212-376	[»]

ProteinModelPortal

Q7WTN6.

SMR

Q7WTN6. Positions 40-200, 212-374.

ModBase

Search...

Protein family/group databases

CAZy

CBM4. Carbohydrate-Binding Module Family 4.
GH10. Glycoside Hydrolase Family 10.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

Gene3D

3.20.20.80. 1 hit.

InterPro

IPR003305. CenC_carb-bd.
IPR008979. Galactose-bd-like.
IPR001000. Glyco_hydro_10.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR026444. Secre_tail.
[Graphical view]

Pfam

PF02018. CBM_4_9. 2 hits.
PF00331. Glyco_hydro_10. 1 hit.
[Graphical view]

SMART

SM00633. Glyco_10. 1 hit.
[Graphical view]

SUPFAM

SSF49785. Gal_bind_like. 2 hits.
SSF51445. Glyco_hydro_cat. 1 hit.

TIGRFAMs

TIGR04183. Por_Secre_tail. 1 hit.

ProtoNet

Search...

Other

EvolutionaryTrace

Q7WTN6.

Entry information

Entry name

Q7WTN6_RHOMR

Accession

Primary (citable) accession number: Q7WTN6

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2003
Last sequence update:	October 1, 2003
Last modified:	April 3, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)