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Q7WTB3 (BGAM_LACHE) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-galactosidase small subunit

Short name=Beta-gal small subunit
EC=3.2.1.23
Alternative name(s):
Lactase small subunit
Gene names
Name:lacM
OrganismLactobacillus helveticus (Lactobacillus suntoryeus)
Taxonomic identifier1587 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Protein attributes

Sequence length318 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Subunit structure

Heterodimer of a large and a small subunit By similarity.

Induction

By lactose. Ref.1

Sequence similarities

Belongs to the bacterial beta-galactosidase small subunit family.

Ontologies

Keywords
   Molecular functionGlycosidase
Hydrolase
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentbeta-galactosidase complex

Inferred from electronic annotation. Source: InterPro

   Molecular_functionbeta-galactosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

carbohydrate binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 318318Beta-galactosidase small subunit
PRO_0000057668

Sequences

Sequence LengthMass (Da)Tools
Q7WTB3 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 0BDB79B71E6D58C1

FASTA31835,895
        10         20         30         40         50         60 
MDYTNNQLHI IYGDATLGVN GKDFQYIFSY ERGGLESLKV HGKEWLYRVP TPTFWRATTD 

        70         80         90        100        110        120 
NDRGSGFNLK AAQWLGADMF TKCTDIHLKV DRHDFAELPI APFNNKFSNH EYAKSAEISF 

       130        140        150        160        170        180 
TYQTLTTPAT NAKIIYNIDD VGHIKVTMRY YGKKGLPPLP VIGIRLIMPT AATGFDYEGL 

       190        200        210        220        230        240 
SGETYPDRMA GAKEGKFHID GLPVTEYLVP QENGMHMQTK KLTINRETTQ NNVDRTNEKF 

       250        260        270        280        290        300 
SLSIQQAEKP FNFSCLPYTA EELENATHIE ELPLVRRTVL VIAGAVRGVG GIDSWGTDVE 

       310 
SAYHINPELD HEFSFILN 

« Hide

References

[1]"Unusual organization for lactose and galactose gene clusters in Lactobacillus helveticus."
Fortina M.G., Ricci G., Mora D., Guglielmetti S., Manachini P.L.
Appl. Environ. Microbiol. 69:3238-3243(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], TRANSCRIPTIONAL REGULATION.
Strain: ATCC 15009 / DSM 20075 / JCM 1120 / NBRC 15019 / NCIMB 11971 / Lh12.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ512877 Genomic DNA. Translation: CAD55500.1.

3D structure databases

ProteinModelPortalQ7WTB3.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH2. Glycoside Hydrolase Family 2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

PATRIC27424867. VBILacHel2059_1299.

Phylogenomic databases

OrthoDBEOG651SX5.

Family and domain databases

Gene3D2.70.98.10. 1 hit.
InterProIPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamPF02929. Bgal_small_N. 1 hit.
[Graphical view]
SMARTSM01038. Bgal_small_N. 1 hit.
[Graphical view]
SUPFAMSSF74650. SSF74650. 1 hit.
ProtoNetSearch...

Entry information

Entry nameBGAM_LACHE
AccessionPrimary (citable) accession number: Q7WTB3
Entry history
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: October 1, 2003
Last modified: November 13, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries