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Q7WR85 (AROK_BORBR) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Shikimate kinase
Short name=SK
EC=2.7.1.71
Gene names
Name:aroK
Ordered Locus Names:BB0071
OrganismBordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus) [Complete proteome] [HAMAP]
Taxonomic identifier257310 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length211 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate By similarity. HAMAP MF_00109

Catalytic activity

ATP + shikimate = ADP + shikimate 3-phosphate. HAMAP MF_00109

Cofactor

Binds 1 magnesium ion per subunit By similarity. HAMAP MF_00109

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7. HAMAP MF_00109

Subunit structure

Monomer By similarity. HAMAP MF_00109

Subcellular location

Cytoplasm Probable HAMAP MF_00109.

Sequence similarities

Belongs to the shikimate kinase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Magnesium
Metal-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

shikimate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 211211Shikimate kinase HAMAP MF_00109
PRO_0000237850

Regions

Nucleotide binding50 – 556ATP By similarity

Sites

Metal binding541Magnesium By similarity
Binding site721Substrate By similarity
Binding site961Substrate By similarity
Binding site1181Substrate; via amide nitrogen By similarity
Binding site1561ATP By similarity
Binding site1751Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7WR85 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: EB8502512BFBD5EA

FASTA21123,083
        10         20         30         40         50         60 
MNASANLCAA SDNDPQPGDQ EAAHPVACAG DEPAAFLPHD LPIFLVGMMG AGKTTIGRGL 

        70         80         90        100        110        120 
ARALRREFID LDHELEARCG VRVPVIFEIE GEAGFRRREA AALQECTQRR QIILATGGGA 

       130        140        150        160        170        180 
VLAAENRQAL RERGIVIYLR ASVEELFRRT SRDRNRPLLA TADPRATLRE LMVAREPLYN 

       190        200        210 
EVADLVIDTG SMPIATLVKS LLPKLQAYEK K

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX640437 Genomic DNA. Translation: CAE30573.1.
RefSeqNP_886624.1. NC_002927.3.

3D structure databases

ProteinModelPortalQ7WR85.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2662361.
GenomeReviewsGene locus BB0071 in contig BX470250_GR.
KEGGbbr:BB0071.
NMPDRfig|257310.1.peg.71.
PATRIC21133346. VBIBorBro124907_0075.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG335815.
OMAVIYLRAN.
PhylomeDBQ7WR85.
ProtClustDBPRK00131.

Enzyme and pathway databases

BioCycBBRO257310:BB0071-MONOMER.

Family and domain databases

HAMAPMF_00109. Shikimate_kinase.
[Tree]
InterProIPR000623. Shikimate_kinase.
IPR023000. Shikimate_kinase_CS.
[Graphical view]
KOK00891.
PfamPF01202. SKI. 1 hit.
[Graphical view]
PRINTSPR01100. SHIKIMTKNASE.
PROSITEPS01128. SHIKIMATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROK_BORBR
AccessionPrimary (citable) accession number: Q7WR85
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: October 1, 2003
Last modified: January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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