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Reviewed, UniProtKB/Swiss-Prot Q7WNY4 (KPRS_BORBR)

Last modified February 9, 2010. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Ribose-phosphate pyrophosphokinase
      Short name=RPPK
    EC=2.7.6.1
Alternative name(s):
    Phosphoribosyl pyrophosphate synthetase
      Short name=P-Rib-PP synthetase
      Short name=PRPP synthetase
Gene names
Name: prs
Synonyms: prsA
Ordered Locus Names: BB0901
OrganismBordetella bronchiseptica (Alcaligenes bronchisepticus) [Complete proteome] [HAMAP]
Taxonomic identifier518 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella

Protein attributes

Sequence length310 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00583

Cofactor

Binds 1 magnesium ion per subunit By similarity. HAMAP MF_00583

Pathway

Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1. HAMAP MF_00583

Subcellular location

Cytoplasm By similarity HAMAP MF_00583.

Sequence similarities

Belongs to the ribose-phosphate pyrophosphokinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 310310Ribose-phosphate pyrophosphokinase HAMAP MF_00583
PRO_0000141112

Regions

Region208 – 22114Binding of phosphoribosylpyrophosphate Potential

Sites

Metal binding1251Magnesium Potential
Metal binding1271Magnesium Potential
Metal binding1361Magnesium Potential
Metal binding1401Magnesium Potential

Sequences

Sequence LengthMass (Da)Tools
Q7WNY4-1 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: EBB858434BDC7802

FASTA31033,481
        10         20         30         40         50         60 
MIFTGTANTR LAVDVVNHLD MSLGKMTVGR FSDGEVMVEI NENVRGKDVF VLQPTCAPTN 

        70         80         90        100        110        120 
DNLMEIMVMV DALRRASAGR ITAAIPYFGY ARQDRRPRSA RVAISAKVVA NMLQVAGVDR 

       130        140        150        160        170        180 
VLTMDLHADQ IQGFFDIPVD NIYAGPILLG DIWRRNFSNL VVVSPDIGGV VRARALAKQL 

       190        200        210        220        230        240 
EADLAIIDKR RPRANVSEVM NIIGEVDGRT CIIMDDMVDT AGTLCKAAQA LKDRGAGAVY 

       250        260        270        280        290        300 
AYCTHPVLSG GAIERIETSS LDELVVTDTI PLSEQGQACG KIRQLSCAAL LGETILRISN 

       310 
AESVSSLFAD 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX640439 Genomic DNA. Translation: CAE31400.1.
RefSeqNP_887450.1.

3D structure databases

SMRQ7WNY4. Positions 1-304.
ModBaseSearch...

Genome annotation databases

GeneID2662705.
KEGGbbr:BB0901.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG519284.
OMAYKTAGAD.
PhylomeDBQ7WNY4.

Enzyme and pathway databases

BioCycBBRO257310:BB0901-MONOMER.
BRENDA2.7.6.1. 413.

Family and domain databases

HAMAPMF_00583_B. RibP_PPkinase_B.
[Tree]
InterProIPR000842. PRib-PP_synthetase_CS.
IPR000836. PRibTrfase.
IPR005946. PRPP_kinase.
[Graphical view]
PfamPF00156. Pribosyltran. 1 hit.
[Graphical view]
TIGRFAMsTIGR01251. ribP_PPkin. 1 hit.
PROSITEPS00114. PRPP_SYNTHETASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKPRS_BORBR
AccessionPrimary (citable) accession number: Q7WNY4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: October 1, 2003
Last modified: February 9, 2010
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents