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Q7WNS8 (PYRF_BORBR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Orotidine 5'-phosphate decarboxylase

EC=4.1.1.23
Alternative name(s):
OMP decarboxylase
Short name=OMPDCase
Short name=OMPdecase
Gene names
Name:pyrF
Ordered Locus Names:BB0957
OrganismBordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus) [Complete proteome] [HAMAP]
Taxonomic identifier257310 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella

Protein attributes

Sequence length273 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processPyrimidine biosynthesis
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_process'de novo' UMP biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

'de novo' pyrimidine nucleobase biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionorotidine-5'-phosphate decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 273273Orotidine 5'-phosphate decarboxylase HAMAP-Rule MF_01215
PRO_1000066457

Sites

Active site951Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7WNS8 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 07BE8813A1653411

FASTA27329,363
        10         20         30         40         50         60 
MTFLKKLEHA WSASQSLLQV GLDPDPKRFP RELEGKPDAI FQFCRDIVDA TAPYACSFKP 

        70         80         90        100        110        120 
QIAYFAAHRA EDQLEALCQH IRAQHPDLPI VLDAKRGDIG STAENYAREA FERYQAHALT 

       130        140        150        160        170        180 
VSPYMGLDSV EPYLAWGDRG VIVLCRTSNP GGSDLQFLKM ADGQPLYLHV AGLVADKWNA 

       190        200        210        220        230        240 
NGQCGLVVGA TFPNELAAVR QRIGDAVPLL VPGIGAQGGD INATVQAGAN SAGAGMMINS 

       250        260        270 
SRAILYASTG EDWRQAAGEA ARGLRDAINA VRT 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX640439 Genomic DNA. Translation: CAE31456.1.
RefSeqNP_887506.1. NC_002927.3.

3D structure databases

ProteinModelPortalQ7WNS8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257310.BB0957.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE31456; CAE31456; BB0957.
GeneID2663472.
KEGGbbr:BB0957.
PATRIC21135141. VBIBorBro124907_0967.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0284.
HOGENOMHOG000245747.
KOK01591.
OMACRTSNAG.
OrthoDBEOG6DZF33.

Enzyme and pathway databases

BioCycBBRO257310:BB0957-MONOMER.
UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_01215. OMPdecase_type2.
InterProIPR013785. Aldolase_TIM.
IPR018089. OMPdecase_AS.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR02127. pyrF_sub2. 1 hit.
PROSITEPS00156. OMPDECASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePYRF_BORBR
AccessionPrimary (citable) accession number: Q7WNS8
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: October 1, 2003
Last modified: May 14, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways