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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA)
  4. Enolase (eno)
  5. Pyruvate kinase (pykA)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei42SubstrateUniRule annotation1
Binding sitei119SubstrateUniRule annotation1
Binding sitei152SubstrateUniRule annotation1
Binding sitei203ATPUniRule annotation1
Binding sitei325ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi351 – 354ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBBRO257310:G1GSX-1400-MONOMER
UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:BB1382
OrganismiBordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus)
Taxonomic identifieri257310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
Proteomesi
  • UP000001027 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001459101 – 397Phosphoglycerate kinaseAdd BLAST397

Proteomic databases

PRIDEiQ7WMK9

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi257310.BB1382

Structurei

3D structure databases

ProteinModelPortaliQ7WMK9
SMRiQ7WMK9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni26 – 28Substrate bindingUniRule annotation3
Regioni65 – 68Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZA Bacteria
COG0126 LUCA
HOGENOMiHOG000227107
KOiK00927
OMAiDMIFDIG
OrthoDBiPOG091H00YN

Family and domain databases

Gene3Di3.40.50.1260, 3 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015911 Phosphoglycerate_kinase_CS
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit
PROSITEiView protein in PROSITE
PS00111 PGLYCERATE_KINASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q7WMK9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNVNTLSAL AKSGALSGKR VFIRADLNVP FDDAGRISED TRIRASVPGI
60 70 80 90 100
RLALDAGAAV MVTSHLGRPK EGALTEADSL APVAQRLSEL LGMQVRLVPD
110 120 130 140 150
WVDGVSVEPG EVVLLENCRG NVGEKKDDEG LSRKMAALCD VYVNDAFGTA
160 170 180 190 200
HRAEATTHGI ARFAPVACAG PLLEAELEAL GRALHDPKRS LVAIVGGSKV
210 220 230 240 250
STKLSILQSL ADKVDQLVVG GGIANTFMLA AGLPIGKSLA EPEQVEQARA
260 270 280 290 300
VIEIMKRRGA EVPIPTDVVC AKSFGADAAA TVKAAADVAE DDMILDIGPQ
310 320 330 340 350
TAQRLADILK AAGTIVWNGP VGVFEFDQFA HGTEVVARAI ADSAGFSIAG
360 370 380 390
GGDTLAAIAK YGIADQTGYI STGGGAFLEF LEGKALPAVA VLQARAA
Length:397
Mass (Da):40,981
Last modified:October 1, 2003 - v1
Checksum:i369D27D2AB5B9052
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX640441 Genomic DNA Translation: CAE31880.1
RefSeqiWP_010926143.1, NC_002927.3

Genome annotation databases

EnsemblBacteriaiCAE31880; CAE31880; BB1382
KEGGibbr:BB1382

Similar proteinsi

Entry informationi

Entry nameiPGK_BORBR
AccessioniPrimary (citable) accession number: Q7WMK9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: October 1, 2003
Last modified: May 23, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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