Reviewed, UniProtKB/Swiss-Prot Q7WMD0 (GLMM_BORBR)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	BB1462

Organism

Bordetella bronchiseptica (Alcaligenes bronchisepticus) [Complete proteome] [HAMAP]

Taxonomic identifier

518 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	452 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 452	452	Phosphoglucosamine mutase HAMAP MF_01554		PRO_0000147854
Sites
	Active site	112	1	Phosphoserine intermediate By similarity
	Metal binding	112	1	Magnesium; via phosphate group By similarity
	Metal binding	251	1	Magnesium By similarity
	Metal binding	253	1	Magnesium By similarity
	Metal binding	255	1	Magnesium By similarity
Amino acid modifications
	Modified residue	112	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7WMD0-1 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 223B0A42E412CD42	FASTA	452	48,300
	10 20 30 40 50 60 MSQRKYFGTD GVRGEVGGPV INAAFALRLG YAAGRVLARE HREHASGRGR NRPQVVIGKD 70 80 90 100 110 120 TRISGYMLES ALEAGLSAAG IDVLLAGPVP TPAVAYLTRT LRLAAGIVIS ASHNPYQDNG 130 140 150 160 170 180 IKFFSAHGMK LPDDIEAAIE QALDEPLGCV GSEELGRARR MADAQGRYIE FCKSTFPHDL 190 200 210 220 230 240 DLNGLKLVVD AAHGAAYNVA PHVFRELGAE VHAIGVSPDG FNINKGVGAL HPESLAEEVR 250 260 270 280 290 300 ARGADLGIAL DGDADRLQMV DGTGRIYNGD ELLYAIVRER MQRGPVAGVV GTLMTNYGLE 310 320 330 340 350 360 RQLQQIGVGF ERANVGDRYV LEQMQARGWL YGGESSGHLL CLDCHTTGDG TIAALQVLTA 370 380 390 400 410 420 LRRADATLAE WVADLRMYPQ KMINVPLAPG LDWKTHDGLA RARGAVEAEL AGRGRVLIRA 430 440 450 SGTEPKLRLM VEAEDEALAQ ASAQKLADSL GA

References

[1]

"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica." Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S. , Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J. Nat. Genet. 35:32-40(2003) [PubMed: 12910271] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RB50 / ATCC BAA-588 / NCTC 13252.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX640441 Genomic DNA. Translation: CAE31959.1.
RefSeq	NP_888007.1.
3D structure databases
SMR	Q7WMD0. Positions 4-444.
ModBase	Search...
Genome annotation databases
GeneID	2663878.
KEGG	bbr:BB1462.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG644964.
OMA	STHPEAM.
PhylomeDB	Q7WMD0.
Enzyme and pathway databases
BioCyc	BBRO257310:BB1462-MONOMER.
BRENDA	5.4.2.10. 413.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_BORBR

Accession

Primary (citable) accession number: Q7WMD0

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	October 1, 2003
Last modified:	February 9, 2010
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)