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Q7WL20 (F16PA_BORBR) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Fructose-1,6-bisphosphatase class 1
Short name=FBPase class 1
EC=3.1.3.11
Alternative name(s):
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Gene names
Name:fbp
Ordered Locus Names:BB1929
OrganismBordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus) [Complete proteome] [HAMAP]
Taxonomic identifier257310 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length339 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP MF_01855

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855

Subunit structure

Homotetramer By similarity. HAMAP MF_01855

Subcellular location

Cytoplasm Potential HAMAP MF_01855.

Sequence similarities

Belongs to the FBPase class 1 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 339339Fructose-1,6-bisphosphatase class 1 HAMAP MF_01855
PRO_0000364468

Regions

Region116 – 1194Substrate binding By similarity

Sites

Metal binding911Magnesium 1 By similarity
Metal binding1131Magnesium 1 By similarity
Metal binding1131Magnesium 2 By similarity
Metal binding1151Magnesium 1; via carbonyl oxygen By similarity
Metal binding1161Magnesium 2 By similarity
Metal binding2821Magnesium 2 By similarity
Binding site2101Substrate By similarity
Binding site2761Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7WL20 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 2FFEF4CD1B56BD29

FASTA33937,198
        10         20         30         40         50         60 
MKRKTLTQYL VEQQRSAQAL GPEVRLLIEV VARACKAISH AVSKGALGGV LGSLESENVQ 

        70         80         90        100        110        120 
GEVQKKLDVL SNEILLEANE WGGHLAAMAS EEMETIHLIP NRYPKGEYLL LFDPLDGSSN 

       130        140        150        160        170        180 
IDVNVSIGTI FSVLRAPHRV AGADVCEQDF LQPGSQQVAA GYAVYGPQTM LVLTIGNGVV 

       190        200        210        220        230        240 
GFTLDREMGS WVLTHESMRI PEDTKEFAIN MSNMRHWAPP VKRYIDECLA GKTGPLGKDY 

       250        260        270        280        290        300 
NMRWIASMVA DVHRILTRGG IFMYPWDARE PGKAGKLRLM YEANPMGLIV EQAGGAAIDG 

       310        320        330 
TGRILDIQPD KLHQRVSVIL GSKNEVERVG RYHAEAHAS

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX640442 Genomic DNA. Translation: CAE32426.1.
RefSeqNP_888474.1. NC_002927.3.

3D structure databases

HSSPHSSP built from PDB template 2GQ1 based on UniProtKB P0A993.
ProteinModelPortalQ7WL20.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2660720.
GenomeReviewsGene locus BB1929 in contig BX470250_GR.
KEGGbbr:BB1929.
PATRIC21137154. VBIBorBro124907_1954.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG731261.
OMAHWEAPVQ.
PhylomeDBQ7WL20.
ProtClustDBPRK09293.

Enzyme and pathway databases

BioCycBBRO257310:BB1929-MONOMER.

Family and domain databases

HAMAPMF_01855. FBPase_class1.
[Tree]
InterProIPR000146. FBPase_class-1/SBPase.
[Graphical view]
KOK03841.
PANTHERPTHR11556. In_FB_phphtase. 1 hit.
PfamPF00316. FBPase. 1 hit.
[Graphical view]
PIRSFPIRSF000904. FBPtase_SBPase. 1 hit.
PRINTSPR00115. F16BPHPHTASE.
PROSITEPS00124. FBPASE. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF16PA_BORBR
AccessionPrimary (citable) accession number: Q7WL20
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: October 1, 2003
Last modified: January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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