Reviewed,
UniProtKB/Swiss-Prot Q7WI34 (GCP_BORBR)
Last modified
November 3, 2009.
Version 34.
History...
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90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Probable O-sialoglycoprotein endopeptidase Short name=Glycoprotease EC=3.4.24.57 | ||||
| Gene names |
| ||||
| Organism | Bordetella bronchiseptica (Alcaligenes bronchisepticus) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 518 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella |
Protein attributes
| Sequence length | 346 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | Hydrolysis of O-sialoglycoproteins; cleaves 31-Arg-|-Asp-32 bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated. HAMAP MF_01445 |
| Cofactor | Zinc Probable. |
| Sequence similarities | Belongs to the peptidase M22 family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | Metal-binding Zinc |
| Molecular function | Hydrolase Metalloprotease Protease |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | proteolysis Inferred from electronic annotation. Source: InterPro |
| Molecular function | metalloendopeptidase activity Inferred from electronic annotation. Source: HAMAP zinc ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 346 | 346 | Probable O-sialoglycoprotein endopeptidase HAMAP MF_01445 | PRO_0000303285 | |||||
Sites | |||||||||
| Metal binding | 111 | 1 | Zinc Potential | ||||||
| Metal binding | 115 | 1 | Zinc Potential | ||||||
Sequences
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References
| [1] | "Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica." Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S. Maskell D.J.Nat. Genet. 35:32-40(2003) [PubMed: 12910271] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RB50 / ATCC BAA-588 / NCTC 13252. |
Cross-references
Sequence databases | |
|---|---|
| BX640446 Genomic DNA. Translation: CAE33514.1. | |
| RefSeq | NP_889558.1. |
3D structure databases | |
| ModBase | Search... |
Protein family/group databases | |
| MEROPS | M22.001. |
Genome annotation databases | |
| GeneID | 2660721. |
| GenomeReviews | Gene locus BB3022 in contig BX470250_GR. |
| KEGG | bbr:BB3022. |
| NMPDR | fig|257310.1.peg.3005. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q7WI34. |
| OMA | CKRALKQ. |
Enzyme and pathway databases | |
| BioCyc | BBRO257310:BB3022-MON. |
| BRENDA | 3.4.24.57. 413. |
Family and domain databases | |
| HAMAP | MF_01445. [Tree] |
| InterPro | IPR009180. Pept_M22_Osialgl. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view] |
| PANTHER | PTHR11735. Pept_M22_Osialgl. 1 hit. |
| Pfam | PF00814. Peptidase_M22. 1 hit. [Graphical view] |
| PRINTS | PR00789. OSIALOPTASE. |
| TIGRFAMs | TIGR00329. gcp. 1 hit. |
| PROSITE | PS01016. GLYCOPROTEASE. False negative. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | GCP_BORBR | ||||||||
| Accession | Primary (citable) accession number: Q7WI34 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Peptidase families Classification of peptidase families and list of entries |
| SIMILARITY comments Index of protein domains and families |

Clusters with


