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Reviewed, UniProtKB/Swiss-Prot Q7WH64 (ACPS_BORBR)

Last modified February 9, 2010. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Holo-[acyl-carrier-protein] synthase
      Short name=Holo-ACP synthase
    EC=2.7.8.7
Alternative name(s):
    4'-phosphopantetheinyl transferase acpS
Gene names
Name: acpS
Ordered Locus Names: BB3345
OrganismBordetella bronchiseptica (Alcaligenes bronchisepticus) [Complete proteome] [HAMAP]
Taxonomic identifier518 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella

Protein attributes

Sequence length153 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein By similarity. HAMAP MF_00101

Catalytic activity

CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein]. HAMAP MF_00101

Cofactor

Magnesium By similarity. HAMAP MF_00101

Subcellular location

Cytoplasm By similarity HAMAP MF_00101.

Sequence similarities

Belongs to the P-Pant transferase superfamily. AcpS family.

Ontologies

Keywords
   Biological processFatty acid biosynthesis
Lipid synthesis
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processfatty acid biosynthetic process

Inferred from electronic annotation. Source: HAMAP

macromolecule biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionholo-[acyl-carrier-protein] synthase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 153153Holo-[acyl-carrier-protein] synthase HAMAP MF_00101
PRO_0000228271

Sites

Metal binding241Magnesium By similarity
Metal binding781Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7WH64-1 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: FC1143C1042D1F5A

FASTA15316,577
        10         20         30         40         50         60 
MSSVSAAGAT PPASPGCIAG IGMDLLRIER IERALARHGD RFAQKILGPE ELAKFHARRR 

        70         80         90        100        110        120 
RDPARGVRFL ATRFAAKEAF SKAIGLGMRM PMSWRRVQTL NAPGGRPVLV IGAELADWFD 

       130        140        150 
ARFGAAHVSI TDESDMAAAY VIVERKPAPD GRP 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX640447 Genomic DNA. Translation: CAE33837.1.
RefSeqNP_889880.1.

3D structure databases

SMRQ7WH64. Positions 16-146.
ModBaseSearch...

Genome annotation databases

GeneID2661311.
KEGGbbr:BB3345.
NMPDRfig|257310.1.peg.3327.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG734479.
OMAQGVFWRD.
PhylomeDBQ7WH64.

Enzyme and pathway databases

BioCycBBRO257310:BB3345-MONOMER.
BRENDA2.7.8.7. 413.

Family and domain databases

HAMAPMF_00101. AcpS.
[Tree]
InterProIPR008278. 4-PPantetheinyl_Trfase.
IPR002582. ACPS.
IPR004568. PPantethiene-prot_Trfase.
[Graphical view]
PfamPF01648. ACPS. 1 hit.
[Graphical view]
ProDomPD004282. PPantethiene-prot_Trfase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR00516. acpS. 1 hit.
TIGR00556. pantethn_trn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameACPS_BORBR
AccessionPrimary (citable) accession number: Q7WH64
Entry history
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: October 1, 2003
Last modified: February 9, 2010
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents