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Q7WGH8 (PPNK_BORBR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable inorganic polyphosphate/ATP-NAD kinase

Short name=Poly(P)/ATP NAD kinase
EC=2.7.1.23
Gene names
Name:ppnK
Ordered Locus Names:BB3940
OrganismBordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus) [Complete proteome] [HAMAP]
Taxonomic identifier257310 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella

Protein attributes

Sequence length299 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP-Rule MF_00361

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP-Rule MF_00361

Cofactor

Divalent metal ions By similarity. HAMAP-Rule MF_00361

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00361.

Sequence similarities

Belongs to the NAD kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processNAD metabolic process

Inferred from electronic annotation. Source: InterPro

NADP biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 299299Probable inorganic polyphosphate/ATP-NAD kinase HAMAP-Rule MF_00361
PRO_0000229613

Sequences

Sequence LengthMass (Da)Tools
Q7WGH8 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 5FE07DEE1C925EA7

FASTA29932,329
        10         20         30         40         50         60 
MYFPIVALIG RYQDTGLDAP LTALAQMLTQ AGRRVLVEAE TARNAGVSGY PVADWDEIGR 

        70         80         90        100        110        120 
TATLAVVMGG DGTVLGAARH LAPYGVPLIG INHGRLGFIT DIPLQDAHDA LGRVLEGNYQ 

       130        140        150        160        170        180 
AEDRMLLQGG VWRGEQQMYS ASAVNDVVLN RAGRGGMIEV RVELDGAFMY TQRADGLIIA 

       190        200        210        220        230        240 
TPTGSTAYSL SANGPILHPG MNAMVLVPVA PQTLSNRPIV IPDSGVLNMT LTAMGRVEIG 

       250        260        270        280        290 
ASVHFDMQTW SDLQPGDRIT VQRAPHTIRF VHPEGYSFFS TLRRKLHWNL MPQATDNLE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX640449 Genomic DNA. Translation: CAE34303.1.
RefSeqNP_890474.1. NC_002927.3.

3D structure databases

ProteinModelPortalQ7WGH8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257310.BB3940.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE34303; CAE34303; BB3940.
GeneID2660754.
KEGGbbr:BB3940.
PATRIC21141285. VBIBorBro124907_4000.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0061.
HOGENOMHOG000227221.
KOK00858.
OMAGMVELRV.
OrthoDBEOG6PZXDR.
ProtClustDBPRK02155.

Enzyme and pathway databases

BioCycBBRO257310:BB3940-MONOMER.

Family and domain databases

Gene3D2.60.200.30. 1 hit.
3.40.50.10330. 1 hit.
HAMAPMF_00361. NAD_kinase.
InterProIPR017438. ATP-NAD_kinase_dom_1.
IPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. PolyP/ATP_NADK_prd.
[Graphical view]
PANTHERPTHR20275. PTHR20275. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. SSF111331. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPNK_BORBR
AccessionPrimary (citable) accession number: Q7WGH8
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: October 1, 2003
Last modified: February 19, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families