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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei91L-glutamineUniRule annotation1
Binding sitei240L-glutamineUniRule annotation1
Binding sitei259ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi59 – 61ATPUniRule annotation3
Nucleotide bindingi65 – 71ATPUniRule annotation7
Nucleotide bindingi294 – 295ATPUniRule annotation2

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:BB4013
OrganismiBordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus)
Taxonomic identifieri257310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
Proteomesi
  • UP000001027 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000954791 – 587Glutamine--tRNA ligaseAdd BLAST587

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi257310.BB4013.

Structurei

3D structure databases

ProteinModelPortaliQ7WGA6.
SMRiQ7WGA6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi58 – 68"HIGH" regionUniRule annotationAdd BLAST11
Motifi301 – 305"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CX6. Bacteria.
COG0008. LUCA.
HOGENOMiHOG000259232.
KOiK01886.
OMAiVTHSICT.
OrthoDBiPOG091H00G9.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPiMF_00126. Gln_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7WGA6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHAPTPPAA SNFLRPIIED DLQANRFQGK LWAGKPGPAA LQAQGQPDPA
60 70 80 90 100
RIRTRFPPEP NGYLHIGHAK SICVNFGLAR DYGGVCHLRF DDTNPEKEEQ
110 120 130 140 150
EYVDAIIEAV HWLGFDWQAD GNDNLYFASD YFEFMYEFAE ALVQAGHAYV
160 170 180 190 200
DEQSAEEIRA SRGTLTEPGT DSPWRDRPAD ESLLRLREMR DGKHPDGSLV
210 220 230 240 250
LRARIDMASP NINLRDPVMY RVRHATHHRT GNAWCIYPMY SWAHPVEDAL
260 270 280 290 300
EGITHSICTL EFEDQRPFYD WILARLAELG KLARPLPHQY EFARLNLTYV
310 320 330 340 350
VTSKRKLLQL VREGYVDGWD DPRMPTLFGL RRRGYTPSSI RLFCDRTAVS
360 370 380 390 400
KSDSRIDYSL LEQAVRDDLD PVAPRSVAVL DPLKLVITNY PEGRSETCSA
410 420 430 440 450
PRNPHDPQAG VREFPFTREL WIEQDDFREE PPKKYFRLFP GNTVRLKYGY
460 470 480 490 500
VVRCTGFTKD QSGKVVEVQA EYLPDTKSGT PGADSVKVKG NITWVSAAHA
510 520 530 540 550
VPAQVHLYDR LFADAHPDGG DKDFLACLNP HSKQTVQAWL EPGIEAVPGA
560 570 580
TWQFERLGYF TVDSKDSRPE APVLNRIVTL RDSWQAA
Length:587
Mass (Da):66,607
Last modified:October 1, 2003 - v1
Checksum:i12A2583015C422BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX640449 Genomic DNA. Translation: CAE34376.1.
RefSeqiWP_010927011.1. NC_002927.3.

Genome annotation databases

EnsemblBacteriaiCAE34376; CAE34376; BB4013.
KEGGibbr:BB4013.

Similar proteinsi

Entry informationi

Entry nameiSYQ_BORBR
AccessioniPrimary (citable) accession number: Q7WGA6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: October 1, 2003
Last modified: August 30, 2017
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families