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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:BB4400
OrganismiBordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus)
Taxonomic identifieri257310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
Proteomesi
  • UP000001027 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001979781 – 277Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST277

Interactioni

Protein-protein interaction databases

STRINGi257310.BB4400

Structurei

3D structure databases

ProteinModelPortaliQ7WF80
SMRiQ7WF80
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DDT Bacteria
COG0639 LUCA
HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP
OrthoDBiPOG091H0691

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

Q7WF80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGSIWTIGD VQGCCAPLAE LLAHPEIAGD TDSRFWFAGD LVNRGPQSLA
60 70 80 90 100
VLRRIMAMGE RCTAVLGNHD LHLLAAYAGV RKPSKSDTLD EVLQAPDAVD
110 120 130 140 150
LIDWLRFRPL AHYEAGHLMV HAGVLAKWDV AKTLALAGEV EQALRGPNWR
160 170 180 190 200
KALQKMYGNE PATWKDDHTG GKRMRVIINA LTRIRLCTPS GHMEFATKVA
210 220 230 240 250
PGAWPAGLVP WFDVPNRATR DVTVVFGHWS TLGLLMRPDV ICLDTGCVWG
260 270
GALSALRLHD RKLVQVKCKR FQDPNGD
Length:277
Mass (Da):30,511
Last modified:October 1, 2003 - v1
Checksum:iDE27E34DEC3404E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX640450 Genomic DNA Translation: CAE34763.1
RefSeqiWP_003814962.1, NC_002927.3

Genome annotation databases

EnsemblBacteriaiCAE34763; CAE34763; BB4400
KEGGibbr:BB4400

Similar proteinsi

Entry informationi

Entry nameiAPAH_BORBR
AccessioniPrimary (citable) accession number: Q7WF80
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: October 1, 2003
Last modified: March 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health