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Q7WDQ0 (SYR_BORBR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:BB4938
OrganismBordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus) [Complete proteome] [HAMAP]
Taxonomic identifier257310 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella

Protein attributes

Sequence length561 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 561561Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151533

Regions

Motif129 – 13911"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q7WDQ0 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 1C5829071C302F09

FASTA56161,517
        10         20         30         40         50         60 
MLLEQQKQLI SLIQAAVAQC LPEAQAQVQL ERPKVAAHGD IATNVAMQLA KPARRNPREL 

        70         80         90        100        110        120 
AQGIVDALMA QPQARELIQD AEIAGPGFIN FRLTPAARQA VVQAVASQAD AYGRAPRNGE 

       130        140        150        160        170        180 
KVLVEFVSAN PTGPLHVGHA RQAALGDAIC RLYDASGWDV TREFYYNDAG NQIDNLAISV 

       190        200        210        220        230        240 
QARGRGIAPD APDYPADGYK GDYIVEIARD FAARKSVQAS DGQPVTATGD LDSLDDIRAF 

       250        260        270        280        290        300 
AVAYLRREQD LDLQAFGLAF DNYFLESSLY ASGRVQETVD TLVAKGHTYE EGGALWLRTT 

       310        320        330        340        350        360 
ELGTGDDKDR VMRKSEGGYT YFVPDVAYHK VKWERGFHHA VNIQGSDHHG TVARVRAGLQ 

       370        380        390        400        410        420 
GLEAGIPKDF PAYVLHKMVK VMRGGEEVKI SKRAGSYVTM RDLIDWVGRD AVRYFLIQRR 

       430        440        450        460        470        480 
ADTEFVFDID LALSKSDENP VYYIQYAHAR ICTMIGNSGA SAAEIAQADT ALLTAPSEYA 

       490        500        510        520        530        540 
LLQRLAEFPQ VVALAAQELA PHHVAFWLRD CASDFHAWYN AERVLVDEPA LKLARLRLAA 

       550        560 
TTRQVLANGL ALLGVSAPDR M 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX640452 Genomic DNA. Translation: CAE35302.1.
RefSeqNP_891472.1. NC_002927.3.

3D structure databases

ProteinModelPortalQ7WDQ0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257310.BB4938.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE35302; CAE35302; BB4938.
GeneID2661661.
KEGGbbr:BB4938.
PATRIC21143382. VBIBorBro124907_5032.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAPRVKGAI.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycBBRO257310:BB4938-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_BORBR
AccessionPrimary (citable) accession number: Q7WDQ0
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: October 1, 2003
Last modified: May 14, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries