Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q7WD73 (KDSA_BORBR) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
2-dehydro-3-deoxyphosphooctonate aldolase
EC=2.5.1.55
Alternative name(s):
3-deoxy-D-manno-octulosonic acid 8-phosphate synthase
KDO-8-phosphate synthase
Short name=KDO 8-P synthase
Short name=KDOPS
Phospho-2-dehydro-3-deoxyoctonate aldolase
Gene names
Name:kdsA
Ordered Locus Names:BB3705
OrganismBordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus) [Complete proteome] [HAMAP]
Taxonomic identifier257310 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length285 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate. HAMAP MF_00056

Pathway

Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3. HAMAP MF_00056

Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. HAMAP MF_00056

Subcellular location

Cytoplasm By similarity HAMAP MF_00056.

Sequence similarities

Belongs to the KdsA family.

Ontologies

Keywords
   Biological processLipopolysaccharide biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processlipopolysaccharide biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-deoxy-8-phosphooctulonate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2852852-dehydro-3-deoxyphosphooctonate aldolase HAMAP MF_00056
PRO_0000187103

Sequences

Sequence LengthMass (Da)Tools
Q7WD73 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 43970E6A37DFB75B

FASTA28530,482
        10         20         30         40         50         60 
MMKACGFDIG LDHPFFLIAG PCVIESRELA FETAGRLKEI TGKLGVSFIY KSSFDKANRS 

        70         80         90        100        110        120 
SGKSFRGPGM DEGLKILADV RAQLDVPVLT DVHDIDQVAP VAAVVDMLQT PAFLCRQTDF 

       130        140        150        160        170        180 
IRACAATLKP VNIKKGQFLA PHDMLQVARK ARDAALEAGG DGNNILVCER GASFGYNNLV 

       190        200        210        220        230        240 
SDMRSLAIMR ETDCPVVFDA THSVQLPGGQ GASSGGQREF VPVLARAAVA VGVAGLFMET 

       250        260        270        280 
HPNPACAMSD GPNAVPLDRM AELLESLVAL DRVTKRSGFL ENQFV

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX640448 Genomic DNA. Translation: CAE35679.1.
RefSeqNP_890240.1. NC_002927.3.

3D structure databases

ProteinModelPortalQ7WD73.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2659892.
GenomeReviewsGene locus BB3705 in contig BX470250_GR.
KEGGbbr:BB3705.
NMPDRfig|257310.1.peg.3687.
PATRIC21140793. VBIBorBro124907_3757.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG575990.
OMAHENEQCA.
PhylomeDBQ7WD73.
ProtClustDBPRK05198.

Enzyme and pathway databases

BioCycBBRO257310:BB3705-MONOMER.

Family and domain databases

HAMAPMF_00056. KDO8P_synth.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006269. KDO8P_synthase.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01627.
PANTHERPTHR21057:SF2. KDO8P_synthase. 1 hit.
PfamPF00793. DAHP_synth_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR01362. KDO8P_synth. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKDSA_BORBR
AccessionPrimary (citable) accession number: Q7WD73
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2004
Last sequence update: October 1, 2003
Last modified: January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents