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Q7WCZ8 (PNCB_BORBR) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:BB3780
OrganismBordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus) [Complete proteome] [HAMAP]
Taxonomic identifier257310 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella

Protein attributes

Sequence length405 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 405405Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_0000205818

Sequences

Sequence LengthMass (Da)Tools
Q7WCZ8 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 093CEDFB4FE82889

FASTA40546,627
        10         20         30         40         50         60 
MVCRNVSRQQ FRAIMIITSL LDTDLYKFSM MQVVLHHFPA AQVEYRYKCR TPGINLRPYL 

        70         80         90        100        110        120 
DEIRAEVHEL CQLRFTSEEL DYLRGLRFIK SDFVDFLGLF HLPERCIFIG EGEQPGEISI 

       130        140        150        160        170        180 
TVKGPWLHTI LFEIPVLAIV NEVYFRNTRR NPDWEEGRKR LQSKMNLVLD DPALADFRVA 

       190        200        210        220        230        240 
EYGTRRRFSK VWHEEIVSTM KARMGVHFAG TSNVLLAMRH GVLPLGTMGH EYLQACQALG 

       250        260        270        280        290        300 
PRLRDSQVFA LEVWAKEYRG DLGIALSDVY GMDAFLRDFD MYFCKLFDGA RHDSGDPFVW 

       310        320        330        340        350        360 
GERLLEHYRA NRADPRAKTL VFSDSLTFPR AIELARQFAG RCKVSFGIGT NLTNDLGHEP 

       370        380        390        400 
LQIVMKMVRC NGQPVAKVSD APEKTMCDDP AYLAYLRQVF QLPPA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX640448 Genomic DNA. Translation: CAE35754.1.
RefSeqNP_890315.1. NC_002927.3.

3D structure databases

ProteinModelPortalQ7WCZ8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257310.BB3780.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE35754; CAE35754; BB3780.
GeneID2659542.
KEGGbbr:BB3780.
PATRIC21140945. VBIBorBro124907_3833.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMAKLTMQCA.
OrthoDBEOG6X10XB.
ProtClustDBPRK05321.

Enzyme and pathway databases

BioCycBBRO257310:BB3780-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERPTHR11098:SF1. PTHR11098:SF1. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_BORBR
AccessionPrimary (citable) accession number: Q7WCZ8
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: October 1, 2003
Last modified: March 19, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways