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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei182 – 1821UniRule annotation
Active sitei627 – 6271UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciBPAR257311:BPP0418-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:BPP0418
OrganismiBordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
Taxonomic identifieri257311 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
ProteomesiUP000001421 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 982982Phosphoenolpyruvate carboxylasePRO_0000166581Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ7WCA9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7WCA9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAYNAPVSN CQFRLTHILP IPQRQGAPTD PFQMNAIRQQ SDSAEPLRHD
60 70 80 90 100
IRLLGRCLGE VIQACEGKRV YDTIETLRRT AVRFRRAGDP ADDKLLQARV
110 120 130 140 150
KQLRGNDPNS VARAFSYFLH LSNIAEDRDQ NRRQRDRALA GAGPERGSLR
160 170 180 190 200
QAIESLKAQG VNNARIRRLL SEACVMPVLT AHPTEVQRKS TLDVHREISS
210 220 230 240 250
LLVQRERELT ADELSELDLA LIGQVATLWQ TRMLRYTRLT VADEIENALS
260 270 280 290 300
YYRSTFLNVI PRVYGDLARL LNREPVKPFT PPPPPLEPFL RMGSWIGGDR
310 320 330 340 350
DGNPNVDAAT LERALLRQAT VLFEHYLQEV HALGAELSAS TLLIEADPAL
360 370 380 390 400
LALADAGGDD SPHRRDEPYR RALIGIYARL AATARHLTGQ ELARRATVPA
410 420 430 440 450
APYDTPDALA ADLAVIAASL SAHHGAPIAR LRLSGLQQAV TVFGFHLATV
460 470 480 490 500
DLRQSSDVHE RVLAELFARA GDGIDGQAVD YLALDEAARV AVLRRELAHA
510 520 530 540 550
RPLASPWIAY SEETASELAV LRAAAAGRAR YGRQAVLQSI VSHTETLSDL
560 570 580 590 600
LEVLVLQKEA GLIAPPGETI APGDGLMVVP LFETIPDLQR GPEIMAAWLD
610 620 630 640 650
LPEVRQRVRL AQGDTQEVML GYSDSNKDGG FLTSNWSLYQ AERALVDVFS
660 670 680 690 700
ARSVRLRMFH GRGGSVGRGG GSSYDAILAQ PPGTVAGQLR LTEQGEVIQS
710 720 730 740 750
KYKDAEVGRW HLELLVAATL ESSLAPQAAA TSAEDAHMQQ HAPAMSFMSE
760 770 780 790 800
LAQRTYRGLV YDTPGFADYF FAATPISEIA GLNIGSRPAS RKKGQHIEDL
810 820 830 840 850
RAIPWGFSWA QCRLMLTGWY GMGSAIEAYL ETGAQGAPRS RRARLAQLRE
860 870 880 890 900
MASDWPAFRT LLSNMEMVLA KSDLAIAAGY AQLVPRRGLR ERVFGAITAE
910 920 930 940 950
HGRTLAMLRL LTRRELLADN PGLMASLRER FAYIDPLNYL QIELIKRHRA
960 970 980
AQRRAGDDAD IRVPRAIHLT INGIAAGLRN SD
Length:982
Mass (Da):108,058
Last modified:October 1, 2003 - v1
Checksum:iD3F349661484A5C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX640424 Genomic DNA. Translation: CAE36002.1.

Genome annotation databases

EnsemblBacteriaiCAE36002; CAE36002; BPP0418.
KEGGibpa:BPP0418.
PATRICi21144424. VBIBorPar43418_0436.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX640424 Genomic DNA. Translation: CAE36002.1.

3D structure databases

ProteinModelPortaliQ7WCA9.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAE36002; CAE36002; BPP0418.
KEGGibpa:BPP0418.
PATRICi21144424. VBIBorPar43418_0436.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciBPAR257311:BPP0418-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica."
    Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S.
    , Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J.
    Nat. Genet. 35:32-40(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 12822 / ATCC BAA-587 / NCTC 13253.

Entry informationi

Entry nameiCAPP_BORPA
AccessioniPrimary (citable) accession number: Q7WCA9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: October 1, 2003
Last modified: July 22, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.