Q7WAB6 (Q7WAB6_BORPA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex EMBL CAE36765.1
EC=2.3.1.12 EMBL CAE36765.1

Gene names

Name:	aceF EMBL CAE36765.1
Ordered Locus Names:	BPP1463

Organism

Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253) [Complete proteome] [HAMAP]

Taxonomic identifier

257311 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella › Bordetella parapertussis

Protein attributes

Sequence length	540 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423 Contains 2 lipoyl-binding domains. RuleBase RU000447

Ontologies

Keywords
Domain	Lipoyl SAAS SAAS003016 RuleBase RU000447
Ligand	Pyruvate EMBL CAE36765.1
Molecular function	Acyltransferase RuleBase RU003765 EMBL CAE36765.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: InterPro
Cellular_component	pyruvate dehydrogenase complex Inferred from electronic annotation. Source: InterPro
Molecular_function	dihydrolipoyllysine-residue acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7WAB6 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 8266657E32C4D3D9	FASTA	540	55,912
	10 20 30 40 50 60 MSNIVEIKVP DIGDFKEVEV IEVLVSAGDT IKAEQSLITV ESDKASMEIP ASAAGVVKSV 70 80 90 100 110 120 KVKVGDKIAE GTVILEVEAA GEAAAAPKAE QAPEAAEAPK ADAAKAEAPA AAGPIEVKVP 130 140 150 160 170 180 DIGDFKEVEV IEVLVAEGDT IKAEQSLITV ESDKASMEIP ASAGGVVQSL KVKVGDKVAM 190 200 210 220 230 240 GTVIAVVQGQ GAAAPAAKAE APAAAEPAAS ASASAPAPAQ RPAPAAALQD EDLKPGQLPH 250 260 270 280 290 300 ASPSVRKFAR ELGVNLSRVT GSAAKGRITA DDVRAYVKQA LSAGAPAGAS GGGDGAALGL 310 320 330 340 350 360 LPWPKIDFTK FGPIEAKPLS RIKKISGANL HRNWVMIPHV TNNDEADITD LEALRVALNK 370 380 390 400 410 420 ENEKSGVKVT MLAFLIKAVV AALKKFPEFN ASLDGDNLVL KQYYHIGFAA DTPNGLVVPV 430 440 450 460 470 480 VRDADKKGIL ELARETSELA RKAREGKVSP AEMQGGCFSI SSLGGIGGTH FTPIINAPEV 490 500 510 520 530 540 AILGVSRSAH KPVWDGKQFV PRLTLPLSLS YDHRVIDGAS AARFNAYLGQ LLADFRRIAL

References

[1]

"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica." Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S. , Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J. Nat. Genet. 35:32-40(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 12822 / ATCC BAA-587 / NCTC 13253.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX640427 Genomic DNA. Translation: CAE36765.1.
RefSeq	NP_883761.1. NC_002928.3.
3D structure databases
ProteinModelPortal	Q7WAB6.
SMR	Q7WAB6. Positions 4-83, 116-193, 302-540.
ModBase	Search...
Protein-protein interaction databases
STRING	257311.BPP1463.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAE36765; CAE36765; BPP1463.
GeneID	1665553.
KEGG	bpa:BPP1463.
PATRIC	21146623. VBIBorPar43418_1521.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000281562.
KO	K00627.
OMA	CMSISSL.
ProtClustDB	PRK11855.
Enzyme and pathway databases
BioCyc	BPAR257311:BPP1463-MONOMER.
Family and domain databases
Gene3D	3.30.559.10. 1 hit. 4.10.320.10. 1 hit.
InterPro	IPR003016. 2-oxoA_DH_lipoyl-BS. IPR001078. 2-oxoacid_DH_actylTfrase. IPR006256. AcTrfase_Pyrv_DH_cplx. IPR000089. Biotin_lipoyl. IPR023213. CAT-like_dom. IPR004167. E3-bd. IPR011053. Single_hybrid_motif. [Graphical view]
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00364. Biotin_lipoyl. 2 hits. PF02817. E3_binding. 1 hit. [Graphical view]
SUPFAM	SSF47005. E3_bd. 1 hit. SSF51230. Hybrid_motif. 2 hits.
TIGRFAMs	TIGR01348. PDHac_trf_long. 1 hit.
PROSITE	PS50968. BIOTINYL_LIPOYL. 2 hits. PS00189. LIPOYL. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7WAB6_BORPA

Accession

Primary (citable) accession number: Q7WAB6

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2003
Last sequence update:	October 1, 2003
Last modified:	May 29, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)