Q7WA62 (GLND_BORPA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	BPP1525

Organism

Bordetella parapertussis [Complete proteome] [HAMAP]

Taxonomic identifier

519 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	865 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity. HAMAP MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277
Sequence similarities	Belongs to the glnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: EC amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 865	865	[Protein-PII] uridylyltransferase HAMAP MF_00277		PRO_0000192719

Sequences

	Sequence		Length	Mass (Da)
	Q7WA62 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: CB4E70700092AB76	FASTA	865	98,453
	10 20 30 40 50 60 MPHVDLNPLK QRMQAARAAA VAQFRQHPRP DMLLTELRRI VDQALRELVK LCPLPAGATL 70 80 90 100 110 120 AAVGGYGRGE LYPHSDVDLL ILLPQPPSAA DARAVEALVA ALWDLGLEPG HSVRTLEDCE 130 140 150 160 170 180 REARGDITVE TALLESRWLA GSRTLMKRLD SAMQARLDAA VFFQAKRVEM QQRHARYQDT 190 200 210 220 230 240 PYALEPNCKE SPGGLRDLQV ILWMARAAGF GHSWREVAQA GLLTSSEARD LRRAEQAFKR 250 260 270 280 290 300 LRIELHLLTG RREDRVLFDL QPGLAAVYGI ASTATRRASE LLMQRYYWAA RLVTQLNVIL 310 320 330 340 350 360 VQNIEERLFP RPDSDARLID DDFRNLRERL DIVREDGFER NPTLLLRAFL VMQQHPELIG 370 380 390 400 410 420 MSARTLRAIW HSRHRIDAQF RRNPVNRKLF LQILQQPRGI VHELRRMTML NILPRYLPVF 430 440 450 460 470 480 RRIVGQMQHD LFHVYTVDQH TLAVVRNLRR FTMPEHAQEY PLASQLIAGL DRHWLLYVAA 490 500 510 520 530 540 LFHDIAKGRG GDHSELGARE VRRFAQDHGL DPADAELVEF LVRHHLLMSA VAQKRDLSDP 550 560 570 580 590 600 QVVRDFAAQV GDERRLAALY LLTVADIRGT SPRVWNAWKG KLLEDLFRLA LAALGGAHAD 610 620 630 640 650 660 AHTVLTERKD EAARLTRLAG LRDDAREAFW NQLDIAYFLR HDASEIAWHT RHLYYQVAPD 670 680 690 700 710 720 EPVVRVRPTE HGEGLQVMVY TRDAPDLFVT TCGYFDAKSL SVQDARVHTT RHGWALDSFI 730 740 750 760 770 780 VLAPEGFADL RAQATLVEHE LAERLRDPHA ARHAHAPRRL PHSHARRSRV FPVMPQAELS 790 800 810 820 830 840 PDERSQSWRL SVTATDRPGL LYALARVFAE HGVDLIMAKI MTLGERVEDV FIVSGSALER 850 860 PRSQMQFERA ILDALAGDEP RQQAA

References

[1]

"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica." Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S. , Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J. Nat. Genet. 35:32-40(2003) [PubMed: 12910271] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 12822 / ATCC BAA-587 / NCTC 13253.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX640427 Genomic DNA. Translation: CAE36827.1.
RefSeq	NP_883815.1. NC_002928.3.
3D structure databases
ProteinModelPortal	Q7WA62.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1665238.
GenomeReviews	Gene locus BPP1525 in contig BX470249_GR.
KEGG	bpa:BPP1525.
NMPDR	fig|257311.1.peg.1449.
PATRIC	21146761. VBIBorPar43418_1589.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG687872.
OMA	MQHDLFH.
PhylomeDB	Q7WA62.
ProtClustDB	PRK03059.
Enzyme and pathway databases
BioCyc	BPAR257311:BPP1525-MONOMER.
Family and domain databases
HAMAP	MF_00277. PII_uridylyl-transf. [Tree]
InterPro	IPR002912. ACT-bd. IPR010043. GlnD_Uridyltrans. IPR023279. HD. IPR003607. Metal-dep_PHydrolase_HD_dom. IPR006674. Metal-dep_PHydrolase_HD_sub. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
Gene3D	G3DSA:1.10.3210.10. HD. 1 hit.
KO	K00990.
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF01842. ACT. 1 hit. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_BORPA

Accession

Primary (citable) accession number: Q7WA62

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 5, 2004
Last sequence update:	October 1, 2003
Last modified:	January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program