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Protein

Glutamate-ammonia-ligase adenylyltransferase

Gene

glnE

Organism
Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Adenylation and deadenylation of glutamate--ammonia ligase.UniRule annotation

Catalytic activityi

ATP + [L-glutamate:ammonia ligase (ADP-forming)]-L-tyrosine = diphosphate + [L-glutamate:ammonia ligase (ADP-forming)]-O(4)-(5'-adenylyl)-L-tyrosine.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

ATP-binding, Magnesium, Nucleotide-binding

Enzyme and pathway databases

BioCyciBPAR257311:BPP1875-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate-ammonia-ligase adenylyltransferaseUniRule annotation (EC:2.7.7.42UniRule annotation)
Alternative name(s):
Glutamine-synthetase adenylyltransferase
Short name:
ATaseUniRule annotation
[Glutamate--ammonia-ligase] adenylyltransferaseUniRule annotation
Gene namesi
Name:glnEUniRule annotation
Ordered Locus Names:BPP1875
OrganismiBordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
Taxonomic identifieri257311 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
Proteomesi
  • UP000001421 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 941941Glutamate-ammonia-ligase adenylyltransferasePRO_0000209232Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ7W993.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni70 – 287218GlnE 1Add
BLAST
Regioni613 – 817205GlnE 2Add
BLAST

Sequence similaritiesi

Belongs to the GlnE family.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

HOGENOMiHOG000256491.
KOiK00982.
OMAiEFMVQYA.

Family and domain databases

HAMAPiMF_00802. GlnE. 1 hit.
InterProiIPR023057. GlnE.
IPR005190. GlnE_rpt_dom.
IPR013546. PII_UdlTrfase/GS_AdlTrfase.
[Graphical view]
PfamiPF08335. GlnD_UR_UTase. 2 hits.
PF03710. GlnE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7W993-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSAPPFAAA LAWSGHLRRR LDAHPDLAAW LANACAHPVS ANVLAAWQAE
60 70 80 90 100
LSGPDAPEVL PVEQCRGMLR KLRERVFLTL IVRDLGGQAD LEEVVGAMTV
110 120 130 140 150
LADIAVGTAY RSVAAELAAV HGLPREQSTG DPQEMLIVGM GKLGGRELNV
160 170 180 190 200
SSDIDLVMLY GDEGETDGPR RISNHEFYGR LTRRMMPALS EVDADGQVFR
210 220 230 240 250
TDLRLRPDGD AGPLAWSLDA LEHYLIGQGR EWERYAWLKA RLMPAQAFAD
260 270 280 290 300
SNPDAQARQL ESLRVPFVYR KYFDFDALAA LRALRERIRQ DWQRRALARN
310 320 330 340 350
GVDSANNIKL GDGGIREIEF IVQLSQLIRG GRMPALQRRG LLEALHAERA
360 370 380 390 400
AGLVPEGDAQ KLEAAYRFLR RTEHALQYRE DEQTHLLPAD PAQRAALAAA
410 420 430 440 450
LGYEPAAFER TLAEHRAFVS QTFRNAFRLA GMGEEDDSPA PARTHANGHA
460 470 480 490 500
MRPHAGALHD IEERLAGQIQ RDFPEHAEDL LRRTETLLGS HRVRSLPDSS
510 520 530 540 550
RHRLEALLPA ALTAAAQTSA PMDAALRLFD LIETIAQRSA YLALLAEYPD
560 570 580 590 600
TLARVARMVA ASPWAAQYLT QHPLLLDSLI DWRTLFEPLD FAQVAHQLAA
610 620 630 640 650
DLDACRLPDG EPDIERQMNL MRDVQRQASF QLLAQNLEGE LTVEKLADQL
660 670 680 690 700
SALADLLLAE TIRRVWPLVN RRPGAEPHLA VIAYGKLGGK ELGYASDLDL
710 720 730 740 750
VFLFDDDRED AAELYAKLGR RMTSWLSTMT SSGRLYEVDL RLRPDGDAGL
760 770 780 790 800
LAVSLEAFEQ YQRSHAWPWE HQALTRARYA AGDTEAGARF ERIRADILVM
810 820 830 840 850
PRDVQALRGE VLGMRDKISA GHPNRSELFD VKHDRGGMVD VEFVTQYLVL
860 870 880 890 900
CHAATHRVLV NNLGNIALLR LAGEAGLIPA PLALAAGDAY RTLRRAQHQL
910 920 930 940
RLKGVDKARV PPGQLAAERA TVCELWQTVL QDGTIAQAEV K
Length:941
Mass (Da):104,312
Last modified:October 1, 2003 - v1
Checksum:i6D35231A5A4C8F01
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX640428 Genomic DNA. Translation: CAE37176.1.
RefSeqiWP_010928254.1. NC_002928.3.

Genome annotation databases

EnsemblBacteriaiCAE37176; CAE37176; BPP1875.
KEGGibpa:BPP1875.
PATRICi21147549. VBIBorPar43418_1974.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX640428 Genomic DNA. Translation: CAE37176.1.
RefSeqiWP_010928254.1. NC_002928.3.

3D structure databases

ProteinModelPortaliQ7W993.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAE37176; CAE37176; BPP1875.
KEGGibpa:BPP1875.
PATRICi21147549. VBIBorPar43418_1974.

Phylogenomic databases

HOGENOMiHOG000256491.
KOiK00982.
OMAiEFMVQYA.

Enzyme and pathway databases

BioCyciBPAR257311:BPP1875-MONOMER.

Family and domain databases

HAMAPiMF_00802. GlnE. 1 hit.
InterProiIPR023057. GlnE.
IPR005190. GlnE_rpt_dom.
IPR013546. PII_UdlTrfase/GS_AdlTrfase.
[Graphical view]
PfamiPF08335. GlnD_UR_UTase. 2 hits.
PF03710. GlnE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLNE_BORPA
AccessioniPrimary (citable) accession number: Q7W993
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: October 1, 2003
Last modified: September 7, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.