Reviewed, UniProtKB/Swiss-Prot Q7W641 (DADA_BORPA)

Names and origin

Protein names

Recommended name:
    D-amino acid dehydrogenase small subunit
    EC=1.4.99.1

Gene names

Name:	dadA
Ordered Locus Names:	BPP3086

Organism

Bordetella parapertussis [Complete proteome] [HAMAP]

Taxonomic identifier

519 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	434 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity.
Catalytic activity	A D-amino acid + H(2)O + acceptor = a 2-oxo acid + NH(3) + reduced acceptor.
Cofactor	FAD By similarity.
Subunit structure	Heterodimer of a small and a large subunit By similarity.
Sequence similarities	Belongs to the dadA oxidoreductase family.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	alanine catabolic process Inferred from electronic annotation. Source: HAMAP oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 434	434	D-amino acid dehydrogenase small subunit		PRO_0000166126
Regions
	Nucleotide binding	3 – 17	15	FAD Potential

Sequences

	Sequence		Length	Mass (Da)
	Q7W641-1 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 5F76538233788D22	FASTA	434	46,907
	10 20 30 40 50 60 MHVIVLGSGV IGTTTAYYLA RQGAQVTVLE RRAGPADETS YGNAGQVSPG YSTPWAAPGI 70 80 90 100 110 120 PLKALKWMFQ KHAPLAIRAD GSFYQWRWLA AMLANCSAGR YSVNKERMLR LAEYSRDCLR 130 140 150 160 170 180 TLRADTGIQY EQRTQGTLQL FRTAAQMEAA RRDIAVLEEC GVPYELLDRN RLPTAEPALA 190 200 210 220 230 240 RALDKLAGGL RLPNDETGDC RRFTLQLADK AKALGVQFRF NQQVEGLDVR GGQVAGVRVG 250 260 270 280 290 300 GEQLAADCYV AAFGSYTRGF LRPLGLDLPV YPVKGYSLTI PMTDESAAPV STILDETYKV 310 320 330 340 350 360 AVTRFDQRIR VGGMAELAGF DLRLKEARRK TLELVVNDLS PGSGAVEQAE FWTGLRPMTP 370 380 390 400 410 420 DSTPIIGATK YGNLFLNTGH GTLGWTMACG SGQLVADQVC GRQPAIRADD LALSRYGAGG 430 QAGGGVARAQ HNAA

References

[1]

"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica." Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S. , Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J. Nat. Genet. 35:32-40(2003) [PubMed: 12910271] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 12822 / ATCC BAA-587 / NCTC 13253.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX640432 Genomic DNA. Translation: CAE38373.1.
RefSeq	NP_885265.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1664791.
GenomeReviews	Gene locus BPP3086 in contig BX470249_GR.
KEGG	bpa:BPP3086.
NMPDR	fig|257311.1.peg.2899.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q7W641.
Enzyme and pathway databases
BioCyc	BPAR257311:BPP3086-MON.
Family and domain databases
HAMAP	MF_01202. [Tree]
InterPro	IPR006076. FAD-dep_OxRdtase. [Graphical view]
Pfam	PF01266. DAO. 1 hit. [Graphical view]
ProDom	PD000139. FAD_pyr_redox. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

DADA_BORPA

Accession

Primary (citable) accession number: Q7W641

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 16, 2004
Last sequence update:	October 1, 2003
Last modified:	November 4, 2008
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)