SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q7W5G3

- PNCB_BORPA

UniProt

Q7W5G3 - PNCB_BORPA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Nicotinate phosphoribosyltransferase
Gene
pncB, BPP3329
Organism
Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate phosphoribosyltransferase activity Source: InterPro
  3. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciBPAR257311:BPP3329-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferase (EC:6.3.4.21)
Short name:
NAPRTase
Gene namesi
Name:pncB
Ordered Locus Names:BPP3329
OrganismiBordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
Taxonomic identifieri257311 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
ProteomesiUP000001421: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 405405Nicotinate phosphoribosyltransferaseUniRule annotation
PRO_0000205819Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi257311.BPP3329.

Structurei

3D structure databases

ProteinModelPortaliQ7W5G3.

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284928.
KOiK00763.
OMAiQAVFHRY.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7W5G3-1 [UniParc]FASTAAdd to Basket

« Hide

MVCRNVSRQQ FRAIMIITSL LDTDLYKFSM MQVVLHHFPA AQVEYRYKCR    50
TPGVNLRPYL DEIRAEVHEL CQLRFTSEEL DYLRGLRFIK SDFVDFLGLF 100
HLPERCIFIG EGEQPGEISI TVKGPWLHTI LFEIPVLAIV NEVYFRNTRR 150
NPDWEEGRKR LQSKMNLVLD DPALADFRVA EYGTRRRFSK VWHEEIVSTM 200
KARMGVHFAG TSNVLLAMRH GVLPLGTMGH EYLQACQALG PRLRDSQVFA 250
LEVWAKEYRG DLGIALSDVY GMDAFLRDFD MYFCKLFDGA RHDSGDPFVW 300
GERLLEHYRA NRADPRAKTL VFSDSLTFPR AIELARQFAG RCKVSFGIGT 350
NLTNDLGHEP LQIVMKMVRC NGQPVAKVSD APEKTMCDDP AYLAYLRQVF 400
QLPPA 405
Length:405
Mass (Da):46,613
Last modified:October 1, 2003 - v1
Checksum:iA2246C77E08659C7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX640433 Genomic DNA. Translation: CAE38614.1.
RefSeqiNP_885495.1. NC_002928.3.

Genome annotation databases

EnsemblBacteriaiCAE38614; CAE38614; BPP3329.
GeneIDi1665900.
KEGGibpa:BPP3329.
PATRICi21150640. VBIBorPar43418_3495.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX640433 Genomic DNA. Translation: CAE38614.1 .
RefSeqi NP_885495.1. NC_002928.3.

3D structure databases

ProteinModelPortali Q7W5G3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 257311.BPP3329.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAE38614 ; CAE38614 ; BPP3329 .
GeneIDi 1665900.
KEGGi bpa:BPP3329.
PATRICi 21150640. VBIBorPar43418_3495.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284928.
KOi K00763.
OMAi QAVFHRY.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci BPAR257311:BPP3329-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica."
    Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S.
    , Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J.
    Nat. Genet. 35:32-40(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 12822 / ATCC BAA-587 / NCTC 13253.

Entry informationi

Entry nameiPNCB_BORPA
AccessioniPrimary (citable) accession number: Q7W5G3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: October 1, 2003
Last modified: September 3, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi