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Q7W4T0 (SYQ_BORPA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine--tRNA ligase

EC=6.1.1.18
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS
Gene names
Name:glnS
Ordered Locus Names:BPP3578
OrganismBordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253) [Complete proteome] [HAMAP]
Taxonomic identifier257311 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella

Protein attributes

Sequence length587 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP-Rule MF_00126

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00126

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00126.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutaminyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

glutamyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glutamine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 587587Glutamine--tRNA ligase HAMAP-Rule MF_00126
PRO_1000095480

Regions

Motif58 – 6811"HIGH" region HAMAP-Rule MF_00126
Motif301 – 3055"KMSKS" region HAMAP-Rule MF_00126

Sites

Binding site3041ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7W4T0 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: FC7144531B1E94C2

FASTA58766,559
        10         20         30         40         50         60 
MTHAPTPPAA SNFLRPIIED DLQANRFQGK LWAGKPGPAA LQAQGQPDPA RIRTRFPPEP 

        70         80         90        100        110        120 
NGYLHIGHAK SICVNFGLAR DYGGVCHLRF DDTNPEKEEQ EYVDAIIEAV HWLGFDWQAD 

       130        140        150        160        170        180 
GNDNLYFASD YFEFMYEFAE ALVQAGHAYV DEQSAEEIRA SRGTLTEPGT DSPWRDRPAD 

       190        200        210        220        230        240 
ESLLRLREMR DGKHPDGSLV LRARIDMASP NINLRDPVMY RVRHATHHRT GNAWCIYPMY 

       250        260        270        280        290        300 
SWAHPVEDAL EGITHSICTL EFEDQRPFYD WILARLAELG KLARPLPHQY EFARLNLTYV 

       310        320        330        340        350        360 
VTSKRKLLQL VREGYVDGWD DPRMPTLFGL RRRGYTPSSI RLFCDRTAVS KSDSRIDYSL 

       370        380        390        400        410        420 
LEQAVRDDLD PVAPRSVAVL DPLKLVITNH PEGRSETCSA PRNPHDPQAG VREFPFTREL 

       430        440        450        460        470        480 
WIEQDDFREE PPKKYFRLFP GNTVRLKYGY VVRCTGFTKD ESGKVVEVQA EYLPDTKSGT 

       490        500        510        520        530        540 
PGADSVKVKG NITWVSAAHA VPAQVHLYDR LFADAHPDGG DKDFLACLNP NSKQTVQAWL 

       550        560        570        580 
EPGIEAVPGA TWQFERLGYF TVDSKDSRPE APVLNRIVTL RDSWQAA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX640434 Genomic DNA. Translation: CAE38862.1.
RefSeqNP_885737.1. NC_002928.3.

3D structure databases

ProteinModelPortalQ7W4T0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257311.BPP3578.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE38862; CAE38862; BPP3578.
GeneID1665905.
KEGGbpa:BPP3578.
PATRIC21151175. VBIBorPar43418_3756.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0008.
HOGENOMHOG000259232.
KOK01886.
OMASREIYID.
OrthoDBEOG6DRPF7.

Enzyme and pathway databases

BioCycBPAR257311:BPP3578-MONOMER.

Family and domain databases

Gene3D1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPMF_00126. Gln_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF50715. SSF50715. 1 hit.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYQ_BORPA
AccessionPrimary (citable) accession number: Q7W4T0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: October 1, 2003
Last modified: May 14, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries