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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei138 – 1381GTPUniRule annotation
Binding sitei142 – 1421GTPUniRule annotation
Binding sitei186 – 1861GTPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi23 – 275GTPUniRule annotation
Nucleotide bindingi107 – 1093GTPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, SeptationUniRule annotation

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciBPAR257311:BPP3747-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:BPP3747Imported
OrganismiBordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)Imported
Taxonomic identifieri257311 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
Proteomesi
  • UP000001421 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

  • Note: Assembles at midcell at the inner surface of the cytoplasmic membrane.UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ7W4B9.
SMRiQ7W4B9. Positions 14-316.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini15 – 204190TubulinInterPro annotationAdd
BLAST
Domaini206 – 324119Tubulin_CInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000049094.
KOiK03531.
OMAiGMAMMGI.

Family and domain databases

Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiIPR000158. Cell_div_FtsZ.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7W4B9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMNFEMLENN AKGTVIKVVG VGGAGGNAVA HMIRSGVSGV DFICANTDAQ
60 70 80 90 100
ALAATNAPVQ IRLGRTGLGA GAKPEQGRAS AETAREEIRA ALNGAHMVFI
110 120 130 140 150
TAGMGGGTGT GAGPVVAEVA KELGILTVGV VTKPFTFEGN KRLRMAEDGI
160 170 180 190 200
GELGKHVHSL IVVLNENLYE LMDDDATQED CFKAADDILH NACAGIAEII
210 220 230 240 250
NVEGNVNVDF EDVKTIMGEQ GQAMMGTAAA SGADRARVAA EKAIACPLLE
260 270 280 290 300
GVDLNGARGV LVNITASRTL KMRETREIME TIRSYASDDA TVIFGTAYDE
310 320 330 340 350
QMGEELRVTV VATGLGREAV RPQLVQHTSE ALRTGTDNMP VGNMLAGQQG
360 370 380 390
DYRGLDMPSV MRNPRSQASA QVRALESSGM DHFDIPAFLR KQAD
Length:394
Mass (Da):41,430
Last modified:October 1, 2003 - v1
Checksum:i06C045C6A24D0D5D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX640434 Genomic DNA. Translation: CAE39030.1.
RefSeqiWP_003814568.1. NC_002928.3.

Genome annotation databases

EnsemblBacteriaiCAE39030; CAE39030; BPP3747.
KEGGibpa:BPP3747.
PATRICi21151535. VBIBorPar43418_3933.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX640434 Genomic DNA. Translation: CAE39030.1.
RefSeqiWP_003814568.1. NC_002928.3.

3D structure databases

ProteinModelPortaliQ7W4B9.
SMRiQ7W4B9. Positions 14-316.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAE39030; CAE39030; BPP3747.
KEGGibpa:BPP3747.
PATRICi21151535. VBIBorPar43418_3933.

Phylogenomic databases

HOGENOMiHOG000049094.
KOiK03531.
OMAiGMAMMGI.

Enzyme and pathway databases

BioCyciBPAR257311:BPP3747-MONOMER.

Family and domain databases

Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiIPR000158. Cell_div_FtsZ.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ7W4B9_BORPA
AccessioniPrimary (citable) accession number: Q7W4B9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: September 7, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.